Givinostat

76 interactions 5 explained in plain English

Also sold as: Duvyzat

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Moxifloxacin Ophthalmic Dolasetron Injection Famotidine Injection Disopyramide Finerenone Oxaliplatin Injection

74 Major 2 Moderate

All (76) Major (74) Moderate (2)

Major

Givinostat Glasdegib Daurismo Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Goserelin Implant Zoladex Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Granisetron Transdermal Patch Sancuso Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Granisetron Injection Granisol Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Histrelin Implant Supprelin Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Ivabradine Corlanor Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Ketoconazole Topical Extina® Foam Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Lefamulin Xenleta Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Lenvatinib Lenvima Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Levofloxacin Levaquin Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Levofloxacin Injection Levaquin Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Loperamide Diamode Increased loperamide exposure, an increased risk of loperamide-related adverse effects and an increased risk of QT interval prolon... Details Givinostat Mefloquine Lariam® Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Metformin Fortamet® Increased metFORMIN exposure and an increased risk of lactic acidosis Details Givinostat Methylergonovine Methergine Increased methylergonovine exposure Details Givinostat Metronidazole Flagyl Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Metronidazole Injection Flagyl Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Metronidazole Topical MetroCream® Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Metronidazole Vaginal MetroGel® Vaginal Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Midostaurin Rydapt Increased CYP3A4 substrate exposure and an increased risk of CYP3A4 substrate-related adverse effects and toxicity Details Givinostat Moxifloxacin Avelox Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Moxifloxacin Injection Avelox Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Nafarelin Nasal Spray Synarel Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Nifedipine Adalat® Increased NIFEdipine exposure Details Givinostat Octreotide Bynfezia Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Octreotide Injection Bynfezia Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Ofloxacin Floxin® Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Ofloxacin Ophthalmic Ocuflox Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Ofloxacin Otic Floxin® Otic Increased risk of QT interval prolongation and torsade de pointes Details Givinostat Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Givinostat Oxaliplatin Injection Eloxatin® Increased risk of QT interval prolongation and torsade de pointes Details

Moderate

Givinostat Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Givinostat Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.