Insulin Detemir (Rdna Origin) Injection

166 interactions 238 cited references

Also sold as: Levemir Levemir®

About Insulin Detemir (Rdna Origin) Injection

Insulin detemir is used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood). It is also used to treat people with type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount… Read the full Insulin Detemir (Rdna Origin) Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Vildagliptin Chlorothiazide Acarbose Alogliptin Bromocriptine Canagliflozin

67 Major 99 Moderate

All (166) Major (67) Moderate (99)

Major

Insulin Detemir (Rdna Origin) Injection Metreleptin Increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Miglitol Glyset® An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Moxifloxacin Avelox Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Detemir (Rdna Origin) Injection Nateglinide Starlix® An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Norfloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Detemir (Rdna Origin) Injection Octreotide Acetate An increased risk of hypoglycemia and impaired glucose regulation Details Insulin Detemir (Rdna Origin) Injection Ofloxacin Floxin® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Detemir (Rdna Origin) Injection Orforglipron Foundayo An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Orlistat Alli An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Pasireotide Diaspartate An increased risk of hypoglycemia and impaired glucose regulation Details Insulin Detemir (Rdna Origin) Injection Pioglitazone Actos Increased risk of fluid retention and heart failure; increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Polythiazide An increased risk of hyperglycemia and an increased insulin requirement Details Insulin Detemir (Rdna Origin) Injection Pramlintide Symlin An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Repaglinide Prandin® An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Rosiglitazone Avandia® Increased risk of fluid retention and heart failure; increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Semaglutide Ozempic An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Sitagliptin Brynovin An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Somatrogon-Ghla Reduced insulin sensitivity Details Insulin Detemir (Rdna Origin) Injection Sotagliflozin Inpefa An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Sparfloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Detemir (Rdna Origin) Injection Testosterone Androderm Increased risk of hypoglycemia (CNS depression, seizures) Details Insulin Detemir (Rdna Origin) Injection Thioctic Acid Increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Tolazamide Tolinase® An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Tolbutamide Orinase® An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Triamterene Dyrenium An increased risk of hyperglycemia and an increased insulin requirement Details Insulin Detemir (Rdna Origin) Injection Trovafloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Detemir (Rdna Origin) Injection Vildagliptin An increased risk of hypoglycemia Details

Moderate

Insulin Detemir (Rdna Origin) Injection Acebutolol Sectral® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Albiglutide An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Aspirin Acuprin® Increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Atenolol Tenormin Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Azilsartan Edarbi Increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Azilsartan Medoxomil Edarbi Increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Balsalazide Colazal Increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Benazepril Lotensin An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Betaxolol Betoptic S Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Bexagliflozin An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Bezafibrate An increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Bismuth Subsalicylate Bismarex Increased risk of hypoglycemia Details Insulin Detemir (Rdna Origin) Injection Bisoprolol Zebeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.