Insulin Detemir

75 interactions 3 explained in plain English

Also sold as: Levemir

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ofloxacin Ophthalmic Miglitol Gemifloxacin Metoclopramide Nasal Spray Orlistat Moxifloxacin Injection

36 Major 39 Moderate

All (75) Major (36) Moderate (39)

Moderate

Insulin Detemir Acebutolol Sectral® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir Benazepril Lotensin An increased risk of hypoglycemia Details Insulin Detemir Azilsartan Edarbi Increased risk of hypoglycemia Details Insulin Detemir Betaxolol Betoptic S Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir Betaxolol Ophthalmic Betoptic® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir Bisoprolol Zebeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir Candesartan Atacand Increased risk of hypoglycemia Details Insulin Detemir Captopril Capoten® An increased risk of hypoglycemia Details Insulin Detemir Clonidine Transdermal Patch Catapres An increased risk of hypoglycemia or hyperglycemia Details Insulin Detemir Disopyramide Norpace Increased risk of hypoglycemia Details Insulin Detemir Dulaglutide Injection Trulicity An increased risk of hypoglycemia Details Insulin Detemir Enalapril Epaned An increased risk of hypoglycemia Details Insulin Detemir Eprosartan Teveten® Increased risk of hypoglycemia Details Insulin Detemir Esmolol Brevibloc Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir Fosinopril Monopril® An increased risk of hypoglycemia Details Insulin Detemir Gemfibrozil Lopid An increased risk of hypoglycemia Details Insulin Detemir Glucagon Injection Baqsimi Decreased blood glucose-lowering effects; interference with glucagon action Details Insulin Detemir Glucagon Injection / Solution Baqsimi Decreased blood glucose-lowering effects; interference with glucagon action Details Insulin Detemir Glucagon Nasal Powder Baqsimi Decreased blood glucose-lowering effects; interference with glucagon action Details Insulin Detemir Irbesartan Avapro Increased risk of hypoglycemia Details Insulin Detemir Labetalol Normodyne® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir Levobunolol Ophthalmic AKBeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir Levothyroxine Ermeza Worsening of glycemic control Details Insulin Detemir Linezolid Injection Zyvox An increased risk of hypoglycemia Details Insulin Detemir Lithium Carbonate Lithobid Hypoglycemia or hyperglycemia Details Insulin Detemir Lixisenatide Injection Adlyxin® An increased risk of hypoglycemia Details Insulin Detemir Losartan Arbli Increased risk of hypoglycemia Details Insulin Detemir Mesalamine Apriso Increased risk of hypoglycemia Details Insulin Detemir Mesalamine Rectal Canasa Increased risk of hypoglycemia Details Insulin Detemir Moexipril Univasc® An increased risk of hypoglycemia Details Insulin Detemir Nadolol Corgard Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir Nebivolol Bystolic Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir Olmesartan Benicar Increased risk of hypoglycemia Details Insulin Detemir Penbutolol Levatol® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Detemir Perindopril Aceon An increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.