Levobunolol Ophthalmic

160 interactions 263 cited references

Also sold as: AKBeta® Betagan Betagan®

About Levobunolol Ophthalmic

Ophthalmic levobunolol is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Levobunolol is in a class of medications called beta blockers. It works by decreasing the pressure in the eye. Read the full Levobunolol Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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30 Major 130 Moderate

All (160) Major (30) Moderate (130)

Moderate

Levobunolol Ophthalmic Bromfenac Bromsite Reduced antihypertensive effect Details Levobunolol Ophthalmic Bufexamac Reduced antihypertensive effect Details Levobunolol Ophthalmic Bunazosin An exaggerated hypotensive response to the first dose of the alpha blocker Details Levobunolol Ophthalmic Canagliflozin Invokana Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Carbimazole Altered metabolism of the beta-adrenergic blocker Details Levobunolol Ophthalmic Celecoxib Celebrex Reduced antihypertensive effect Details Levobunolol Ophthalmic Chlorpropamide Diabinese® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Choline Salicylate Reduced antihypertensive effect Details Levobunolol Ophthalmic Clonixin Reduced antihypertensive effect Details Levobunolol Ophthalmic Dapagliflozin Farxiga Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Deslanoside Increased risk of bradycardia and possible digitalis glycoside toxicity Details Levobunolol Ophthalmic Dexibuprofen Reduced antihypertensive effect Details Levobunolol Ophthalmic Dexketoprofen Reduced antihypertensive effect Details Levobunolol Ophthalmic Diclofenac Aleve Arthritis Pain Reduced antihypertensive effect Details Levobunolol Ophthalmic Diflunisal Dolobid Reduced antihypertensive effect Details Levobunolol Ophthalmic Digitoxin Increased risk of bradycardia and possible digitalis glycoside toxicity Details Levobunolol Ophthalmic Digoxin Cardoxin® Increased risk of bradycardia and possible digitalis glycoside toxicity Details Levobunolol Ophthalmic Dipyrone Reduced antihypertensive effect Details Levobunolol Ophthalmic Doxazosin Cardura An exaggerated hypotensive response to the first dose of the alpha blocker Details Levobunolol Ophthalmic Droxicam Reduced antihypertensive effect Details Levobunolol Ophthalmic Dulaglutide Trulicity Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Empagliflozin Glyxambi® (as a combination product containing Empagliflozin and Linagliptin) Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Ertugliflozin Steglatro Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Etodolac Lodine Reduced antihypertensive effect Details Levobunolol Ophthalmic Etofenamate Reduced antihypertensive effect Details Levobunolol Ophthalmic Etoricoxib Reduced antihypertensive effect Details Levobunolol Ophthalmic Etrasimod Velsipity May increase the risk of transient decrease in heart rate Details Levobunolol Ophthalmic Exenatide Bydureon Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Felbinac Reduced antihypertensive effect Details Levobunolol Ophthalmic Fenoprofen Fenopron Reduced antihypertensive effect Details Levobunolol Ophthalmic Fepradinol Reduced antihypertensive effect Details Levobunolol Ophthalmic Feprazone Reduced antihypertensive effect Details Levobunolol Ophthalmic Floctafenine Reduced antihypertensive effect Details Levobunolol Ophthalmic Flufenamic Acid Reduced antihypertensive effect Details Levobunolol Ophthalmic Flurbiprofen Ansaid Reduced antihypertensive effect Details Levobunolol Ophthalmic Glimepiride Amaryl Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Glipizide Glucotrol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Glucagon A transient increase in pulse and blood pressure Details Levobunolol Ophthalmic Glyburide DiaBeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Ibuprofen Addaprin Reduced antihypertensive effect Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.