Levobunolol Ophthalmic

160 interactions 263 cited references
Also sold as: AKBeta® Betagan Betagan®
About Levobunolol Ophthalmic

Ophthalmic levobunolol is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Levobunolol is in a class of medications called beta blockers. It works by decreasing the pressure in the eye. Read the full Levobunolol Ophthalmic drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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30 Major 130 Moderate
All (160) Major (30) Moderate (130)

Moderate

Levobunolol Ophthalmic Fepradinol Reduced antihypertensive effect Details Levobunolol Ophthalmic Feprazone Reduced antihypertensive effect Details Levobunolol Ophthalmic Floctafenine Reduced antihypertensive effect Details Levobunolol Ophthalmic Flufenamic Acid Reduced antihypertensive effect Details Levobunolol Ophthalmic Flurbiprofen Ansaid Reduced antihypertensive effect Details Levobunolol Ophthalmic Glimepiride Amaryl Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Glipizide Glucotrol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Glucagon A transient increase in pulse and blood pressure Details Levobunolol Ophthalmic Glyburide DiaBeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Ibuprofen Addaprin Reduced antihypertensive effect Details Levobunolol Ophthalmic Indomethacin Indocin Reduced antihypertensive effect Details Levobunolol Ophthalmic Insulin Aspart, Recombinant Fiasp Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Insulin Degludec Tresiba Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Insulin Detemir Levemir Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Insulin Glargine, Recombinant Basaglar Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Insulin Glulisine Apidra Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Insulin Human Inhaled Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Insulin Human Isophane (Nph) Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Insulin Human Regular Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Insulin Lispro, Recombinant Admelog Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Ketoprofen Actron® Reduced antihypertensive effect Details Levobunolol Ophthalmic Ketorolac Acular Reduced antihypertensive effect Details Levobunolol Ophthalmic Lidoflazine Hypotension, bradycardia, and AV conduction disturbances Details Levobunolol Ophthalmic Linagliptin Tradjenta Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Liraglutide Saxenda Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Lixisenatide Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Lornoxicam Reduced antihypertensive effect Details Levobunolol Ophthalmic Loxoprofen Reduced antihypertensive effect Details Levobunolol Ophthalmic Lumiracoxib Reduced antihypertensive effect Details Levobunolol Ophthalmic Ma Huang Reduced hypotensive effect of beta-adrenergic blockers Details Levobunolol Ophthalmic Meclofenamate Meclodium® Reduced antihypertensive effect Details Levobunolol Ophthalmic Mefenamic Acid Ponstel® Reduced antihypertensive effect Details Levobunolol Ophthalmic Meloxicam Alloxate Reduced antihypertensive effect Details Levobunolol Ophthalmic Metformin Fortamet® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Methacholine Impaired reversal of methacholine-caused bronchoconstriction Details Levobunolol Ophthalmic Methimazole Felanorm Altered metabolism of the beta-adrenergic blocker Details Levobunolol Ophthalmic Methyldopa Aldomet® Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Levobunolol Ophthalmic Metildigoxin Increased risk of bradycardia and possible digitalis glycoside toxicity Details Levobunolol Ophthalmic Miglitol Glyset® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Levobunolol Ophthalmic Morniflumate Reduced antihypertensive effect Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.