Lornoxicam

91 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Ophthalmic Ketorolac Ketorolac Nasal Spray Ketorolac Injection Diclofenac Ophthalmic Ibuprofen
4 Contraindicated 59 Major 28 Moderate
All (91) Contraindicated (4) Major (59) Moderate (28)

Major

Lornoxicam Hydrocortisone Ala-Cort Increased risk of gastrointestinal ulcer or bleeding Details Lornoxicam Hydrocortisone Injection A-Hydrocort® Increased risk of gastrointestinal ulcer or bleeding Details Lornoxicam Ibuprofen Addaprin An increased risk of gastrointestinal toxicity Details Lornoxicam Iloprost Aurlumyn An increased risk of bleeding Details Lornoxicam Ketoprofen Actron® Increased risk of bleeding Details Lornoxicam Lithium Carbonate Lithobid Increased lithium exposure and an increased risk of lithium toxicity Details Lornoxicam Meclofenamate Meclodium® Increased risk of bleeding Details Lornoxicam Mefenamic Acid Ponstel® Increased risk of bleeding Details Lornoxicam Meloxicam Alloxate Increased risk of bleeding Details Lornoxicam Meloxicam Injection Alloxate Increased risk of bleeding Details Lornoxicam Melphalan Alkeran An increased risk of bleeding Details Lornoxicam Melphalan Injection Alkeran An increased risk of bleeding Details Lornoxicam Mesalamine Apriso Increased risk of bleeding Details Lornoxicam Mesalamine Rectal Canasa Increased risk of bleeding Details Lornoxicam Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Lornoxicam Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Lornoxicam Nabumetone Relafen Increased risk of bleeding Details Lornoxicam Naproxen Aleve Increased risk of bleeding Details Lornoxicam Pemetrexed Injection Alimta Increased PEMEtrexed exposure and an increased risk of PEMEtrexed toxicity (myelosuppression, renal toxicity, and gastrointestinal... Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.