Mifepristone

225 interactions 13 explained in plain English
Also sold as: Korlym Mifeprex
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Hydrocortisone Neratinib Ciclesonide Oral Inhalation Diflorasone Topical Clindamycin Topical Desonide
69 Contraindicated 139 Major 17 Moderate
All (225) Contraindicated (69) Major (139) Moderate (17)

Major

Mifepristone Nisoldipine Sular Increased CYP3A4 substrate exposure Details Mifepristone Octreotide Bynfezia An increased risk of QT interval prolongation Details Mifepristone Octreotide Injection Bynfezia An increased risk of QT interval prolongation Details Mifepristone Ofloxacin Floxin® An increased risk of QT interval prolongation Details Mifepristone Ofloxacin Ophthalmic Ocuflox An increased risk of QT interval prolongation Details Mifepristone Ofloxacin Otic Floxin® Otic An increased risk of QT interval prolongation Details Mifepristone Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Mifepristone Oxaliplatin Injection Eloxatin® Increased risk of QT-interval prolongation Details

Moderate

Mifepristone Diclofenac Ophthalmic Voltaren® Eye Drops Increased NSAID exposure Details Mifepristone Diclofenac Topical (Actinic Keratosis) Pennsaid Increased NSAID exposure Details Mifepristone Diclofenac Topical (Arthritis Pain) Pennsaid® Increased NSAID exposure Details Mifepristone Diclofenac Transdermal Patch Flector Increased NSAID exposure Details Mifepristone Erlotinib Tarceva Increased erlotinib exposure Details Mifepristone Flurbiprofen Ansaid Increased NSAID exposure Details Mifepristone Flurbiprofen Ophthalmic Ocufen Increased NSAID exposure Details Mifepristone Fluvastatin Lescol Increased fluvastatin exposure Details Mifepristone Glimepiride Amaryl Increased exposure to glimepiride Details Mifepristone Glipizide Glucotrol Increased exposure to glipiZIDE Details Mifepristone Ibuprofen Addaprin Increased NSAID exposure Details Mifepristone Irbesartan Avapro Increased exposure to irbesartan Details Mifepristone Levothyroxine Ermeza Decreased levothyroxine efficacy Details Mifepristone Losartan Arbli Increased exposure to losartan Details Mifepristone Meloxicam Alloxate Increased NSAID exposure Details Mifepristone Meloxicam Injection Alloxate Increased NSAID exposure Details Mifepristone Nimodipine Nimotop Increased nimodipine serum levels Details

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