Moxifloxacin Ophthalmic

282 interactions 387 cited references

Also sold as: Moxeza® Vigamox Vigamox®

About Moxifloxacin Ophthalmic

Moxifloxacin ophthalmic solution is a fluoroquinolone antibiotic used to treat bacterial eye infections like pink eye. Read the full Moxifloxacin Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Mesoridazine Pimozide Piperaquine Saquinavir Sparfloxacin

12 Contraindicated 251 Major 19 Moderate

All (282) Contraindicated (12) Major (251) Moderate (19)

Major

Moxifloxacin Ophthalmic Tolbutamide Orinase® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Moxifloxacin Ophthalmic Tolterodine Detrol Increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Toremifene Fareston Increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Tramadol ConZip An increased risk of seizure Details Moxifloxacin Ophthalmic Trazodone Raldesy Increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Triamcinolone Aller-Cort An increased risk of tendon rupture Details Moxifloxacin Ophthalmic Triclabendazole Egaten An increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Trimipramine Increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Triptorelin Increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Vandetanib Caprelsa Increased risk of QT-interval prolongation Details Moxifloxacin Ophthalmic Vardenafil Levitra Increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Vemurafenib Zelboraf Increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Venlafaxine Increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Vepdegestrant Veppanu An increased risk of QT interval prolongation and an increased risk of torsade de pointes, polymorphic ventricular tachycardia, ot... Details Moxifloxacin Ophthalmic Vilanterol An increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Vinflunine Increased risk of QT-interval prolongation Details Moxifloxacin Ophthalmic Voclosporin Lupkynis An increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Voglibose Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Moxifloxacin Ophthalmic Voriconazole Vfend Increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Vorinostat Zolinza Increased risk of QT interval prolongation Details Moxifloxacin Ophthalmic Warfarin Coumadin Increased risk of bleeding Details Moxifloxacin Ophthalmic Ziftomenib Komzifti An increased risk of QT interval prolongation and torsade de pointes Details Moxifloxacin Ophthalmic Zuclopenthixol An increased risk of QT interval prolongation Details

Moderate

Moxifloxacin Ophthalmic Aluminum Carbonate, Basic Decreased oral moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Aluminum Hydroxide AlternaGEL® Decreased oral moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Aluminum Phosphate Decreased oral moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Aminolevulinic Acid Increased risk of phototoxic skin reaction (ie, severe sunburn) Details Moxifloxacin Ophthalmic Dandelion Decreased fluoroquinolone effectiveness Details Moxifloxacin Ophthalmic Didanosine Videx® Decreased moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Dihydroxyaluminum Aminoacetate Decreased oral moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Dihydroxyaluminum Sodium Carbonate Decreased oral moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Iron Decreased moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Lanthanum Carbonate Fosrenol Reduced bioavailability of quinolone antibiotics Details Moxifloxacin Ophthalmic Magaldrate Decreased oral moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Magnesium Carbonate Decreased oral moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Magnesium Hydroxide Almacone® (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone) Decreased oral moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Magnesium Oxide Mag-Ox 400 Decreased oral moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Magnesium Trisilicate Decreased oral moxifloxacin effectiveness Details Moxifloxacin Ophthalmic Quercetin Reduced fluoroquinolone effectiveness Details Moxifloxacin Ophthalmic Strontium Ranelate Decreased bioavailability and exposure of strontium ranelate Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.