Nafarelin Nasal Spray

Name: Nafarelin Nasal Spray Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

85 interactions 200 cited references

Also sold as: Synarel Synarel®

About Nafarelin Nasal Spray

Nafarelin nasal spray is used to manage endometriosis (a condition in which the type of tissue that lines the uterus [womb] grows in other areas of the body and causes infertility, pain before and during menstrual periods, pain during and after sexual activity, and heavy or irregular bleeding). Nafarelin nasal spray is… Read the full Nafarelin Nasal Spray drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Pimozide Mesoridazine Levoketoconazole Dronedarone Bepridil Cisapride

12 Contraindicated 73 Major

All (85) Contraindicated (12) Major (73)

Major

Nafarelin Nasal Spray Vemurafenib Zelboraf Increased risk of QT-interval prolongation Details Nafarelin Nasal Spray Vepdegestrant Veppanu An increased risk of QT interval prolongation and an increased risk of torsade de pointes, polymorphic ventricular tachycardia, ot... Details Nafarelin Nasal Spray Voclosporin Lupkynis An increased risk of QT interval prolongation Details Nafarelin Nasal Spray Ziftomenib Komzifti An increased risk of QT interval prolongation and torsade de pointes Details Nafarelin Nasal Spray Zuclopenthixol An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.