Pexidartinib
59 interactions 4 explained in plain EnglishPexidartinib is used to treat tenosynovial giant cell tumors (TGCT; tumors in or around a joint that can cause pain, swelling, and reduce movement) in adults that cannot be treated by surgery. Pexidartinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that… Read the full Pexidartinib drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Pexidartinib Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse effects Details Pexidartinib Lumateperone Caplyta Reduced lumateperone exposure Details Pexidartinib Lurasidone Latuda Reduced lurasidone exposure Details Pexidartinib Maraviroc Selzentry Hepatotoxicity Details Pexidartinib Meloxicam Alloxate Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Pexidartinib Meloxicam Injection Alloxate Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Pexidartinib Methotrexate Jylamvo Hepatotoxicity Details Pexidartinib Methotrexate Injection Abitrexate® Hepatotoxicity Details Pexidartinib Mexiletine Mexitil® Hepatotoxicity Details Pexidartinib Mitapivat Aqvesme Reduced mitapivat exposure and reduced efficacy of mitapivat Details Pexidartinib Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Pexidartinib Nevirapine Viramune Hepatotoxicity Details Pexidartinib Nifedipine Adalat® Reduced NIFEdipine exposure Details Pexidartinib Oxandrolone Oxandrin Hepatotoxicity Details Pexidartinib Pentostatin Injection Nipent Hepatotoxicity DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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