Primidone

Major

Primidone Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of CNS depression and reduced codeine exposure Details Primidone Clindamycin ANTIROBE Explained Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Omeprazole Gastrobim Explained Reduced omeprazole exposure, reduced efficacy of omeprazole, increased PHENobarbital exposure and an increased risk of PHENobarbit... Details Primidone Amitriptyline Elavil Explained Reduced tricyclic antidepressant exposure and possible additive adverse effects Details Primidone Sertraline Explained An increased risk of QT interval prolongation Details Primidone Buprenorphine Belbuca Explained An increased risk of QT interval prolongation, an increased risk of CNS depression, reduced buprenorphine exposure and reduced eff... Details Primidone Colchicine Colcrys Explained Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Simvastatin Flolipid Explained Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Abemaciclib Verzenio Explained Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Abrocitinib Cibinqo Explained Reduced abrocitinib exposure and reduced efficacy of abrocitinib Details Primidone Acalabrutinib Calquence Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Acetazolamide Diamox® Sequels® Reduced serum concentrations of primidone and its metabolites and decreased anticonvulsant effect Details Primidone Amisulpride Injection Barhemsys An increased risk of QT interval prolongation Details Primidone Apixaban Eliquis Explained Reduced apixaban exposure and an increased risk of thrombotic events Details Primidone Arsenic Trioxide Trisenox An increased risk of QT interval prolongation Details Primidone Aripiprazole Injection Abilify An increased risk of QT interval prolongation, an increased risk of CNS depression, reduced ARIPiprazole exposure and reduced effi... Details Primidone Arsenic Trioxide Injection Trisenox An increased risk of QT interval prolongation Details Primidone Asenapine Transdermal Patch Secuado An increased risk of QT interval prolongation and an increased risk of CNS depression Details Primidone Atogepant Qulipta Reduced atogepant exposure Details Primidone Avapritinib Ayvakit Reduced avapritinib exposure and reduced efficacy of avapritinib Details Primidone Avatrombopag Doptelet Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Azithromycin AzaSite An increased risk of QT interval prolongation Details Primidone Belumosudil Rezurock Explained Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Atorvastatin Atorvaliq Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Cariprazine Vraylar Explained Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Primidone Abiraterone Abirtega Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Aficamten Reduced aficamten exposure and reduced efficacy of aficamten Details Primidone Alfuzosin UroXatral An increased risk of QT interval prolongation, reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Amlodipine Amvaz® Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Anagrelide Agrylin An increased risk of QT interval prolongation Details Primidone Avanafil Stendra Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Axitinib Inlyta Reduced axitinib exposure Details Primidone Bedaquiline Sirturo An increased risk of QT interval prolongation, reduced bedaquiline exposure and reduced efficacy of bedaquiline Details Primidone Bosutinib Bosulif Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Brigatinib Alunbrig Decreased brigatinib exposure and efficacy Details Primidone Budesonide Entocort Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Budesonide Nasal Spray Rhinocort Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Budesonide Oral Inhalation Pulmicort Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Primidone Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details