Primidone

Major

Primidone Hydroxychloroquine Plaquenil Impaired antiepileptic activity and an increased risk of QT interval prolongation Details Primidone Ibrexafungerp Brexafemme Decreased ibrexafungerp plasma concentrations Details Primidone Ibrutinib Imbruvica Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Ifosfamide Injection Ifex Increased neurotoxic and nephrotoxic effects, reduced ifosfamide exposure and reduced efficacy of ifosfamide Details Primidone Infigratinib Truseltiq Decreased infigratinib plasma concentrations Details Primidone Inotuzumab Ozogamicin Injection Besponsa An increased risk of QT interval prolongation Details Primidone Irbesartan Avapro Reduced CYP2C9 substrate exposure and reduced efficacy of CYP2C9 substrate Details Primidone Irinotecan Camptosar Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Irinotecan Injection Camptosar Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Irinotecan Lipid Complex Injection Onivyde® Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Istradefylline Nourianz Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Ivabradine Corlanor An increased risk of QT interval prolongation, reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Ixazomib Ninlaro Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Ketoconazole Topical Extina® Foam An increased risk of QT interval prolongation Details Primidone Lacosamide Injection Motpoly An increased risk of CNS depression Details Primidone Lansoprazole Prevacid Reduced CYP2C19 substrate exposure and reduced efficacy of CYP2C19 substrate Details Primidone Lefamulin Xenleta Reduced lefamulin exposure, reduced efficacy of lefamulin and an increased risk of QT interval prolongation Details Primidone Lenacapavir Injection Sunlenca Reduced lenacapavir exposure which may result in the loss of therapeutic effect and development of resistance to lenacapavir Details Primidone Lenacapavir Oral Sunlenca Reduced lenacapavir exposure which may result in the loss of therapeutic effect and development of resistance to lenacapavir Details Primidone Leniolisib Joenja Reduced leniolisib exposure and reduced efficacy of leniolisib Details Primidone Lenvatinib Lenvima An increased risk of QT interval prolongation Details Primidone Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Primidone Levofloxacin Levaquin An increased risk of QT interval prolongation Details Primidone Levofloxacin Injection Levaquin An increased risk of QT interval prolongation Details Primidone Levonorgestrel After banger Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Primidone Levonorgestrel Intrauterine System Kyleena Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Primidone Linagliptin Tradjenta Reduced linagliptin exposure Details Primidone Losartan Arbli Reduced CYP2C9 substrate exposure and reduced efficacy of CYP2C9 substrate Details Primidone Lovastatin Altocor® Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Primidone Lumateperone Caplyta Reduced lumateperone exposure Details Primidone Lurasidone Latuda Reduced lurasidone exposure Details Primidone Medroxyprogesterone Amen® Reduced medroxyPROGESTERone exposure Details Primidone Medroxyprogesterone Injection Depo-Provera Reduced medroxyPROGESTERone exposure Details Primidone Mefloquine Lariam® An increased risk of QT interval prolongation, reduced PHENobarbital exposure and reduced efficacy of PHENobarbital Details Primidone Methylphenidate Adhansia XR® Increased PHENobarbital exposure Details Primidone Methylphenidate Transdermal Patch Daytrana Increased PHENobarbital exposure Details Primidone Metoclopramide Injection Gimoti Increased risk of CNS depression Details Primidone Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Primidone Metronidazole Flagyl An increased risk of QT interval prolongation, reduced metroNIDAZOLE exposure and reduced metroNIDAZOLE efficacy Details Primidone Metronidazole Injection Flagyl An increased risk of QT interval prolongation, reduced metroNIDAZOLE exposure and reduced metroNIDAZOLE efficacy Details