Warfarin
210 interactions 9 explained in plain English
Also sold as:
Coumadin
Jantoven
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
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Major
Warfarin Abametapir Explained Increased exposure of CYP1A2 substrates Details Warfarin Omeprazole Gastrobim Explained Altered warfarin exposure and altered INR Details Warfarin Sertraline Explained An increased risk of bleeding, increased sertraline exposure and an increased risk of sertraline-related adverse events Details Warfarin Simvastatin Flolipid Explained An increased INR and increased risk of bleeding Details Warfarin Acyclovir Avaclyr Increased warfarin exposure and an increased INR Details Warfarin Acyclovir Injection Avaclyr Increased warfarin exposure and an increased INR Details Warfarin Acyclovir Ophthalmic Avaclyr Increased warfarin exposure and an increased INR Details Warfarin Adalimumab Injection Abrilada Altered warfarin exposure Details Warfarin Acyclovir Topical Zovirax Increased warfarin exposure and an increased INR Details Warfarin Allopurinol Aloprim Increased INR Details Warfarin Allopurinol Injection Aloprim Increased INR Details Warfarin Amoxicillin Amoxi Drop Increased INR and increased risk of bleeding Details Warfarin Ampicillin Amcill® An increased risk of bleeding Details Warfarin Ampicillin Injection Omnipen-N® An increased risk of bleeding Details Warfarin Apixaban Eliquis Explained An increased risk of bleeding and can cause serious, potentially fatal bleeding Details Warfarin Asciminib Scemblix Increased CYP2C9/CYP3A4 substrates with NTI exposure and an increased risk of CYP2C9/CYP3A4 substrates-related side effects Details Warfarin Aspirin Acuprin® Increased risk of bleeding, prolongation of both bleeding and prothrombin time Details Warfarin Aspirin Rectal Aspirin Increased risk of bleeding, prolongation of both bleeding and prothrombin time Details Warfarin Azathioprine Azasan Reduced anticoagulant effect of warfarin Details Warfarin Azithromycin AzaSite An increased risk of bleeding Details Warfarin Betrixaban Bevyxxa® Increased risk of bleeding Details Warfarin Bicalutamide Casodex Increased warfarin exposure, an increased INR and increased risk of bleeding Details Warfarin Amlodipine Amvaz® Increased warfarin exposure and an increased INR Details Warfarin Anagrelide Agrylin An increased risk of bleeding Details Warfarin Bromfenac Ophthalmic Bromday® An increased risk of bleeding Details Warfarin Cabozantinib Cabometyx Increased risk of bleeding Details Warfarin Cabozantinib (Thyroid Cancer) Cabometyx Increased risk of bleeding Details Warfarin Capecitabine Xeloda Increased warfarin exposure and an increased risk of altered coagulation parameters and/or bleeding including death Details Warfarin Caplacizumab-Yhdp Injection Cablivi An increased risk of bleeding Details Warfarin Capmatinib Tabrecta Increased warfarin exposure and an increased INR Details Warfarin Carboplatin Kyxata Increased risk for elevated INR and subsequent bleeding Details Warfarin Carboplatin Injection Kyxata Increased risk for elevated INR and subsequent bleeding Details Warfarin Cefadroxil Duricef® An increased risk of bleeding Details Warfarin Cefdinir Omnicef® An increased risk of bleeding Details Warfarin Cefepime Injection Maxipime® An increased risk of bleeding Details Warfarin Cefixime Suprax An increased risk of bleeding Details Warfarin Cefotaxime Injection Claforan An increased risk of bleeding Details Warfarin Ceftaroline Injection Teflaro® An increased risk of INR elevation and increased risk of bleeding Details Warfarin Ceftazidime Injection Fortaz An increased risk of bleeding Details Warfarin Ceftriaxone Injection Rocephin® An increased risk of bleeding DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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