Warfarin
210 interactions 9 explained in plain English
Also sold as:
Coumadin
Jantoven
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
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Major
Warfarin Clopidogrel Plavix An increased risk of bleeding Details Warfarin Cyclophosphamide Cytoxan® Increased risk for elevated INR and subsequent bleeding Details Warfarin Cyclophosphamide Injection Cytoxan® Injection Increased risk for elevated INR and subsequent bleeding Details Warfarin Cyclosporine Injection Atopica Increased warfarin exposure, increased INR and reduced efficacy of cycloSPORINE and warfarin Details Warfarin Cyclosporine Ophthalmic Cequa Increased warfarin exposure, increased INR and reduced efficacy of cycloSPORINE and warfarin Details Warfarin Dabigatran Pradaxa® An increased risk of bleeding Details Warfarin Dabigatran Etexilate An increased risk of bleeding Details Warfarin Dalteparin Injection Fragmin An increased risk of bleeding Details Warfarin Danazol Danocrine® An increased risk of bleeding Details Warfarin Dapsone Aczone Increased International Normalized Ratio (INR) Details Warfarin Dapsone Topical Aczone Increased International Normalized Ratio (INR) Details Warfarin Deferasirox Exjade Increased warfarin exposure Details Warfarin Dexamethasone Injection Decadron Increased risk of bleeding, altered (increased or reduced) warfarin exposure and an altered INR Details Warfarin Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased risk of bleeding, altered (increased or reduced) warfarin exposure and an altered INR Details Warfarin Diclofenac Ophthalmic Voltaren® Eye Drops An increased risk of bleeding Details Warfarin Diclofenac Topical (Actinic Keratosis) Pennsaid An increased risk of bleeding Details Warfarin Diclofenac Topical (Arthritis Pain) Pennsaid® An increased risk of bleeding Details Warfarin Diclofenac Transdermal Patch Flector An increased risk of bleeding Details Warfarin Dipyridamole Permole® An increased risk of bleeding Details Warfarin Disulfiram Antabuse Increased warfarin exposure, an increased risk of bleeding and an increased INR Details Warfarin Doxorubicin Adriamycin Increased risk for elevated INR and subsequent bleeding Details Warfarin Doxycycline Injection Acticlate An increased risk of bleeding Details Warfarin Edoxaban Savaysa Increased risk of bleeding Details Warfarin Enasidenib Idhifa Increased CYP1A2 substrate exposure and an increased risk of CYP1A2 substrate-related adverse effects Details Warfarin Enoxaparin Lovenox An increased risk of bleeding Details Warfarin Enoxaparin Injection Lovenox An increased risk of bleeding Details Warfarin Entacapone Comtan Increased warfarin exposure and increased risk for bleeding Details Warfarin Epoprostenol Flolan An increased risk of bleeding Details Warfarin Erlotinib Tarceva An increased risk of bleeding Details Warfarin Estradiol Delestrogen Altered warfarin exposure, reduced or increased anticoagulant effectiveness and altered INR Details Warfarin Estradiol Topical Divigel Altered warfarin exposure, reduced or increased anticoagulant effectiveness and altered INR Details Warfarin Estradiol Transdermal Patch Alora® Altered warfarin exposure, reduced or increased anticoagulant effectiveness and altered INR Details Warfarin Etodolac Lodine An increased risk of bleeding Details Warfarin Famotidine Calmicid Increased warfarin exposure and an increased INR Details Warfarin Famotidine Injection Calmicid Increased warfarin exposure and an increased INR Details Warfarin Fenoprofen Fenopron An increased risk of bleeding Details Warfarin Fluorouracil Adrucil Increased warfarin exposure and an increased risk of altered coagulation parameters and/or bleeding including death Details Warfarin Fluorouracil Injection Adrucil Increased warfarin exposure and an increased risk of altered coagulation parameters and/or bleeding including death Details Warfarin Fluorouracil Topical Carac Increased warfarin exposure and an increased risk of altered coagulation parameters and/or bleeding including death Details Warfarin Flurbiprofen Ansaid An increased risk of bleeding DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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