Ziprasidone

88 interactions 6 explained in plain English

Also sold as: Geodon

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ivabradine Octreotide Injection Hydroxychloroquine Ofloxacin Otic Linezolid Injection Amisulpride Injection

64 Contraindicated 22 Major 2 Moderate

All (88) Contraindicated (64) Major (22) Moderate (2)

Contraindicated

Ziprasidone Amitriptyline Elavil Explained Increased risk of QT interval prolongation and an increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, men... Details Ziprasidone Sertraline Explained Increased risk of QT interval prolongation and an increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, men... Details Ziprasidone Buprenorphine Belbuca Explained An increased risk of QT interval prolongation, an increased risk of serotonin syndrome and an increased risk of respiratory and CN... Details Ziprasidone Relugolix Orgovyx Explained An increased risk of QT interval prolongation Details Ziprasidone Amisulpride Injection Barhemsys An increased risk of QT interval prolongation Details Ziprasidone Arsenic Trioxide Trisenox An increased risk of QT interval prolongation Details Ziprasidone Aripiprazole Injection Abilify An increased risk of QT interval prolongation and an increased risk of CNS depression Details Ziprasidone Arsenic Trioxide Injection Trisenox An increased risk of QT interval prolongation Details Ziprasidone Asenapine Transdermal Patch Secuado An increased risk of QT interval prolongation and an increased risk of CNS depression Details Ziprasidone Azithromycin AzaSite An increased risk of QT interval prolongation Details Ziprasidone Alfuzosin UroXatral An increased risk of QT interval prolongation Details Ziprasidone Anagrelide Agrylin An increased risk of QT interval prolongation Details Ziprasidone Bedaquiline Sirturo An increased risk of QT interval prolongation Details Ziprasidone Chloroquine Aralen® An increased risk of QT interval prolongation Details Ziprasidone Dasatinib Phyrago An increased risk of QT interval prolongation Details Ziprasidone Degarelix Injection Firmagon An increased risk of QT interval prolongation Details Ziprasidone Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Ziprasidone Disopyramide Norpace Increased risk of QT interval prolongation Details Ziprasidone Dofetilide Tikosyn Increased risk of QT interval prolongation Details Ziprasidone Dolasetron Anzemet Increased risk of QT interval prolongation and an increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, men... Details Ziprasidone Dolasetron Injection Anzemet Increased risk of QT interval prolongation and an increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, men... Details Ziprasidone Encorafenib Braftovi An increased risk of QT interval prolongation Details Ziprasidone Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Ziprasidone Eribulin Injection Halaven An increased risk of QT interval prolongation Details Ziprasidone Famotidine Calmicid An increased risk of QT interval prolongation Details Ziprasidone Famotidine Injection Calmicid An increased risk of QT interval prolongation Details Ziprasidone Felbamate Felbatol An increased risk of QT interval prolongation Details Ziprasidone Flecainide Tambocor® An increased risk of QT interval prolongation Details Ziprasidone Foscarnet Injection Foscavir An increased risk of QT interval prolongation Details Ziprasidone Galantamine Razadyne An increased risk of QT interval prolongation Details Ziprasidone Gatifloxacin Ophthalmic Zymar® An increased risk of QT interval prolongation Details Ziprasidone Gemifloxacin Factive An increased risk of QT interval prolongation Details Ziprasidone Glasdegib Daurismo An increased risk of QT interval prolongation Details Ziprasidone Goserelin Implant Zoladex An increased risk of QT interval prolongation Details Ziprasidone Granisetron Transdermal Patch Sancuso Increased risk of QT interval prolongation and an increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, men... Details Ziprasidone Granisetron Injection Granisol Increased risk of QT interval prolongation and an increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, men... Details Ziprasidone Histrelin Implant Supprelin An increased risk of QT interval prolongation Details Ziprasidone Hydroxychloroquine Plaquenil An increased risk of QT interval prolongation Details Ziprasidone Inotuzumab Ozogamicin Injection Besponsa An increased risk of QT interval prolongation Details Ziprasidone Ivabradine Corlanor An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.