Vyondys Generic: When Will Generic Golodirsen Be Available?

Dr. Brian Staiger, PharmD, BCPS

This page is aggregated from FDA records, court filings and company announcements. Coded and designed by

Updated October 9, 2026 How we build our data

Vyondys Generic at a Glance

Four quick answers from FDA records and our estimate.

  1. When is the first generic expected? June 2028 About a year and a half away Why then?
  2. Has the FDA approved a generic? Unknown No FDA Orange Book record under this name
  3. When does the brand’s protection end? Unknown Not in the FDA record we could read
  4. Can you buy a generic today? Not yet No company lists one for sale

Explains

PharmD, BCPS · Clinical pharmacist Updated

Generic golodirsen is expected to be available in June 2028, about a year and a half away. None is for sale yet.

Why June 2028?

A patent that protects the brand runs out. After that, approved generics can be sold. We rate it toss-up: still unsettled. Just as likely to slip as to hold.

Will the generic cost less?

Usually, but no company is recorded as having applied to make one yet, and a single company usually brings only a modest drop. See the price pattern

What should I do now?

Keep taking Vyondys as prescribed. When a generic arrives, your pharmacy may switch you to it automatically, and it may look different. What a generic means for you

Our month is only an estimate based on available information, so we never name a day.

Vyondys by the Numbers

Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

Vyondys’s Road to a Generic

The first generic of Vyondys is expected in June 2028.

Why that month: a patent that protects the brand runs out. After that, approved generics can be sold.

Brand alone on the market Approval date not in the Orange Book
Brand alone on the market First generic expected Swipe the chart sideways to see every year.

The bar shows Vyondys on the market on its own until the month we expect the first generic (the green band), a month and never a day. Its approval date and patents are not in the FDA Orange Book under this name, so the bar fades in from the left. The expected month comes from court records and company announcements.

Who Is Lined Up to Make Generic Golodirsen

Three steps stand between a brand and a generic you can buy: a company applies to the FDA, the FDA approves it, and the company starts selling it.

1

Applied to the FDA

No company is recorded as having applied to the FDA to make a generic Vyondys yet.

2

Approved by the FDA

We could not find Vyondys’s own record in the FDA Orange Book under this name, so the approved generic makers are not shown.

3

For Sale in Pharmacies

Not yet. No company lists a generic golodirsen for sale with the FDA.

Sources: how many companies have applied, from court records and company announcements; approved generics from the FDA Orange Book; what is for sale from the FDA NDC Directory. The FDA does not disclose an application before it approves it (21 CFR 314.430).

Vyondys Price: What Pharmacies Pay and What Generics Usually Do

What a Generic Could Cost

How we estimate it. The national survey of what pharmacies pay (NADAC) has no recent price for Vyondys, so we cannot show dollars. Here is the FDA’s finding of how far the price pharmacies pay usually falls as generic companies join: about 31% with one company, 44% with two, 73% with four and over 95% with six or more (the typical drop for every drug whose first generic came out from 2015 to 2017).

Median prices pharmacies paid for the generic (invoice prices), compared with the brand’s price before generic entry, from FDA’s 2019 analysis “Generic Competition and Drug Prices”. At the manufacturer’s price FDA found steeper drops (about 39%, 54%, 79% and over 95%), the figures quoted elsewhere on this tracker. A typical pattern, not a price quote for this medicine.

What a Generic Vyondys Means for You

Nothing Changes Until It Is in Pharmacies

Until a generic is actually for sale, keep filling Vyondys as usual. When one arrives, there is nothing you need to sign up for.

Your Pharmacy May Switch You Automatically

Every state lets pharmacists fill a brand-name prescription with an FDA-approved generic rated as equivalent to it, and about 19 states require them to, unless your prescriber writes “dispense as written” or “brand medically necessary” on the prescription. Some states ask the pharmacist to tell you, or to get your OK first. A study of every state’s law has the details.

It Will Probably Look Different

US trademark law does not let a generic look exactly like the brand, so the color, shape or markings usually change. The active ingredient, strength and form are the same. An “authorized generic,” made by or for the brand’s own company, can look identical. The FDA explains.

Your Insurance May Change Too

Once a lower-cost version is available, many insurance plans charge more for the brand, or stop covering it. Your plan’s drug list (formulary) says how.

Until a generic is on US pharmacy shelves, be careful with websites that offer “generic Vyondys”. The FDA warns that unlicensed online pharmacies sell counterfeit and unapproved medicines; its BeSafeRx page shows how to check a pharmacy.

Ask a pharmacist about Vyondys

Questions people ask about Vyondys

Is there a generic for Vyondys right now?

No. As of October 9, 2026 no generic golodirsen is listed for sale in the FDA NDC Directory.

When will Vyondys go generic?

June 2028 is the expected month, and that is toss-up but not certain. A patent that protects the brand runs out. After that, approved generics can be sold.

Will generic golodirsen be the same as Vyondys?

Yes in the ways that matter: the same active ingredient, strength and form, with proof that it reaches your blood the same way. Inactive ingredients can differ, which is why some people notice a different look or taste.

How much will the generic cost?

Nobody can say for sure before launch. No company is recorded as having applied to the FDA to make one yet, and a single company usually brings only a modest drop.

Changes to This Projection

  • First generic expected June 2028 on this month’s schedule. A line is added here whenever a monthly update moves the month, the reason or how sure it is.

Every change to the expected month is logged here with the month we saw it.

Also Going Generic

All upcoming generics

About Vyondys

  • Generic name golodirsen
  • How it is taken Into a vein (IV)
  • Hard to copy Inhalers, injectables, patches and other hard-to-copy products. Fewer companies attempt them and dates slip more often.
  • More drugs Brand-name drugs starting with V
  • Have a question? A pharmacist answers, free. Ask about Vyondys

Sources. The expected month: FDA Paragraph IV Patent Certifications list, federal court records, company announcements and securities filings (settlement dates, launch plans, sales). The record on this page: FDA Orange Book, FDA NDC Directory, FDA, Generic Competition and Drug Prices (2019). Updated October 9, 2026. Information, not medical advice.