Drug & supplement interaction

Andrachne + Botulinum Toxin Type A

Botulinum Toxin Type A brand name: Botox.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Andrachne and Botulinum Toxin Type A in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Andrachne and Botulinum Toxin Type A

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Botulinum Toxin Type A and Andrachne in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Andrachne at all — not against Botulinum Toxin Type A, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Andrachne safety at a glance

Andrachne overall Not established There is very little reliable safety data on Andrachne in humans.
Pregnancy Avoid Safety is unknown, so it is best to avoid use during pregnancy.
Breastfeeding Avoid There is no safety data during breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Botulinum Toxin Type A and Andrachne? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
From our Q&A

Questions About Andrachne or Botulinum Toxin Type A

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Andrachne or Botulinum Toxin Type A, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

How much people look this up

Where Andrachne and Botulinum Toxin Type A Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Andrachne
Steady interest

#1,084 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Botulinum Toxin Type A
Top 25%

#322 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Andrachne is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Andrachne reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Andrachne and Botulinum Toxin Type A records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Andrachne

What is Andrachne?

Andrachne
  • Fever
  • Diarrhea
  • Urinary tract complaints
  • Antimicrobial support
  • Antioxidant support

Andrachne is a group of flowering plants used in some traditional medicine systems for fever, diarrhea, and urinary problems, but there is very little human research to support these uses. Because its safety has not been well studied, it is best to be cautious and talk with a pharmacist or doctor before trying it.

Phyllanthaceae · Leaves, stems, and roots · Traditional teas, decoctions, and crude plant extracts

An interaction check asks whether these two react with each other — it does not ask whether Andrachne is a good idea for someone in your situation. Here is what our Andrachne record says about it on its own.

Andrachne: dosing

There is no established or standardized dose for Andrachne. Because it has not been well studied, experts cannot recommend a safe and effective amount.If you are considering a product that contains Andrachne, follow the directions on the label and do not exceed them.

From our Andrachne monograph — the full record covers uses, side effects and every documented interaction.

Read the full Andrachne monograph & all interactions
Medication

About OnabotulinumtoxinA Injection

What Is OnabotulinumtoxinA Injection Used For?

Brand name: Botox

Botox is approved to treat a wide range of conditions in adults and some children. These include overactive bladder (OAB) with urge incontinence, urinary incontinence caused by nerve-related bladder overactivity (in adults and in children aged 5 and older), prevention of headaches in adults with chronic migraine (15 or more headache days per month), muscle stiffness (spasticity) in patients aged 2 and older, cervical dystonia (abnormal head position and neck pain), severe underarm sweating (primary axillary hyperhidrosis) when topical treatments haven't worked, eyelid spasms (blepharospasm) in patients aged 12 and older, and crossed eyes (strabismus) in patients aged 12 and older.

BOTOX Cosmetic is a separate product containing the same active ingredient but with its own approved cosmetic uses. Both products are given by injection and are not interchangeable with other botulinum toxin products. Botox has not been shown to work for episodic migraine (14 or fewer headache days per month), and its safety for excessive sweating in body areas other than the underarms has not been established.

Most-Reported Side Effects for Botulinum Toxin Type A

From FAERS, the FDA’s public side-effect reporting system (12,344 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Headache 1,596 reports
Drug intolerance 1,333 reports
Nausea 1,266 reports
Migraine 1,176 reports
Dizziness 1,126 reports
See full OnabotulinumtoxinA Injection drug information
Keep checking

Other Drugs & Andrachne

Browse every other medication we’ve checked against Andrachne — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Andrachne References

The 3 sources that drive our Andrachne monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Andrachne is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Phyllanthaceae and related medicinal plants — MedlinePlus Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source
  3. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Andrachne and Botulinum Toxin Type A Together: Common Questions

Is it safe to take Andrachne with Botulinum Toxin Type A?
We do not list a known interaction between Andrachne and Botulinum Toxin Type A. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Botulinum Toxin Type A and Andrachne?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.