Drug & supplement interaction

Androstenetrione + Meclofenamate

Meclofenamate brand name: Meclomen.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Androstenetrione and Meclofenamate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Meclofenamate states a food rule worth keeping to.

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Interaction report

Androstenetrione and Meclofenamate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Meclofenamate and Androstenetrione in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Androstenetrione safety at a glance

Androstenetrione overall Use caution Limited safety data and hormone-related side effects make this a risky supplement.
Pregnancy Possibly Unsafe When used orally. There is no scientifically reliable information available about using androstenetrione during pregnancy or lactation. Promoters indicate that... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally. There is no scientifically reliable information available about using androstenetrione during pregnancy or lactation. Promoters indicate that... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Meclofenamate and Androstenetrione? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Meclofenamate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Meclofenamate is filed under 5 classifications — including nonsteroidal anti-inflammatory drugs (nsaids), organic anion transporter 3 (oat3) substrates, organic anion transporter 1 (oat1) substrates. Androstenetrione has documented interactions with 1 drug class — the most serious being androgens (minor) — and none of Meclofenamate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Androstenetrione Does Interact With Other Medications

Androstenetrione has 9 minor known drug interactions in our database — Meclofenamate isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Androstenetrione

Covers the 2,830 medications we’ve checked against Androstenetrione. Pick one to open its full report.

What to actually watch for

What Androstenetrione Itself Has Been Linked To

This is not an interaction — nothing below involves Meclofenamate. It is the side-effect record for Androstenetrione on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Androstenetrione, this list is the first place to look.

  • Breast tenderness / Acne Additional detail

    “Theoretically, androstenetrione might cause testosterone-like side effects including spermatogenesis and infertility, acne, testicular atrophy, gynecomastia, behavioral changes, cardiovascular disease, and potentially increase the risk of pancreatic and prostate cancer.”

    Androstenetrione · Natural Medicines adverse-effect record, reported in infertility.

Everything above comes from the Natural Medicines adverse-effect record for Androstenetrione — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Meclofenamate’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Meclofenamate column appears here.

Special populations

Androstenetrione in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally. There is no scientifically reliable information available about using androstenetrione during pregnancy or lactation. Promoters indicate that it can increase testosterone levels. If this is true, this product may not be safe due to the adverse effects associated with elevated testosterone levels; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Meclofenamate Products Have a Food Rule — Androstenetrione Should Not Break It

At least one FDA label for a product containing Meclofenamate says to take it with food. If you take Androstenetrione on an empty stomach out of habit, keep them separate — and take Meclofenamate with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Meclofenamate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

If gastrointestinal complaints occur (see WARNINGS and PRECAUTIONS ), meclofenamate sodium may be administered with meals or with milk (see CLINICAL PHARMACOLOGY for a description of food effects).

From the Dosage and Administration section of the FDA label we read for Meclofenamate — where that label names a specific product, the instruction is that product's. See the Meclofenamate drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Meclofenamate

This page covers Androstenetrione only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Meclofenamate page lists 32 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 16 moderate · 11 minor.

From our pharmacist’s overview on the Meclofenamate page

“Meclofenamate (Meclomen) is a prescription NSAID for pain and arthritis, a class of drug that is already hard on the stomach and kidneys, so this list deserves real care rather than a quick skim. Five of its 32 supplement and herbal interactions rate major, clustered around two dangers: alcohol (beer and wine both raise the risk of sto…”

Reviewed by 2 · Jul 18, 2026

Open the Meclofenamate interaction page

One more smart check

Taking Androstenetrione as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Androstenetrione, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Androstenetrione. Even though Androstenetrione itself has no known interaction with Meclofenamate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Androstenetrione and Meclofenamate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Androstenetrione
Steady interest

#1,055 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Meclofenamate
Steady interest

#1,883 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Androstenetrione is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Androstenetrione reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Androstenetrione and Meclofenamate records this page draws on were last updated October 6, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Androstenetrione

What is Androstenetrione?

Androstenetrione
  • Boosting testosterone
  • Lowering estrogen
  • Bodybuilding and muscle building
  • Post-cycle support for steroid users
  • Athletic performance

Androstenetrione (6-OXO) is a synthetic compound marketed to raise testosterone by blocking the enzyme that turns testosterone into estrogen. Solid human evidence that it offers real benefits is lacking, and it can cause hormone-related side effects, so most people should avoid it and talk with a healthcare provider first.

Synthetic compound (not from a plant) · Capsules, tablets

An interaction check asks whether these two react with each other — it does not ask whether Androstenetrione is a good idea for someone in your situation. Here is what our Androstenetrione record says about it on its own.

Androstenetrione: dosing

There is no established, standardized dose for androstenetrione, and no dose has been proven safe and effective. Different products contain different amounts.Because of the hormone-related risks and weak evidence, we cannot recommend a specific amount.

From our Androstenetrione monograph — the full record covers uses, side effects and every documented interaction.

Read the full Androstenetrione monograph & all interactions
Medication

About Meclofenamate

What Is Meclofenamate Used For?

Brand name: Meclomen

Meclofenamate sodium capsules are used in adults to reduce fever and to relieve mild to moderate pain. They are also used for signs and symptoms of juvenile arthritis, rheumatoid arthritis and osteoarthritis.

They are also used for primary dysmenorrhea (painful periods) and idiopathic heavy menstrual blood loss (heavy periods with no known cause). They can be used short term or long term for ankylosing spondylitis, acute painful shoulder and acute gouty arthritis. The capsules are not recommended in children, because safety and effectiveness have not been studied.

See full Meclofenamate drug information Meclofenamate Sodium NDC codes and packages
Keep checking

Other Drugs & Androstenetrione

Browse every other medication we’ve checked against Androstenetrione — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
9Minor
2,820No known interaction
Minor

9 interactions

No interaction 2,820 drugs checked — show the list
Evidence & sources

Androstenetrione References

The 3 sources that drive our Androstenetrione monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Androstenetrione is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements for Exercise and Athletic Performance — NIH Office of Dietary Supplements Source
  2. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  3. Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Androstenetrione and Meclofenamate Together: Common Questions

Is it safe to take Androstenetrione with Meclofenamate?
We do not list a known interaction between Androstenetrione and Meclofenamate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Androstenetrione and Meclofenamate at the same time of day?
At least one FDA label for a product containing Meclofenamate says to take it with food. If you take Androstenetrione on an empty stomach out of habit, keep them separate and take Meclofenamate with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Meclofenamate products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Androstenetrione and Meclofenamate combination checked?
Interactions in our licensed database are recorded against drug classes. Meclofenamate is filed under 5 classifications, and Androstenetrione has documented interactions with 1 drug class — none of Meclofenamate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Androstenetrione interact with any other medications?
Yes. Androstenetrione has 9 documented drug interactions in our database — Meclofenamate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Meclofenamate interact with any supplements?
Yes. Meclofenamate has documented interactions with 32 supplements in our database — Androstenetrione is not one of them. The Meclofenamate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Meclofenamate and Androstenetrione?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.