Antioxidants + Norgestrel
Norgestrel brand names: Ovrette, Orval 21.
We found no known interaction between Antioxidants and Norgestrel in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Antioxidants and Norgestrel
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Norgestrel and Antioxidants in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Antioxidants at all — not against Norgestrel, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Antioxidants safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Antioxidants in Pregnancy & Breastfeeding
When certain antioxidants are used orally and appropriately during pregnancy. See monographs of specific ingredients for more information.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Norgestrel
This page covers Antioxidants only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Norgestrel page lists 188 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).
By severity: 6 major · 140 moderate · 42 minor.
From our pharmacist’s overview on the Norgestrel page
“Norgestrel (Ovrette) is a progestin-only birth control pill, so the biggest danger on this page is not a strange side effect but a pill that quietly stops working. That risk makes this a page for genuine vigilance.”
Reviewed by 2 · Jul 18, 2026
Where Antioxidants and Norgestrel Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,228 of 1,452 supplements looked up here in the last 7 days
#2,063 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Antioxidants reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Antioxidants and Norgestrel records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Antioxidants
What is Antioxidants?
- General wellness and aging
- Heart health support
- Eye health
- Immune support
- Skin health
Antioxidants are compounds—like vitamins C and E, selenium, and many plant chemicals—that help protect your cells from a type of damage called oxidative stress. Getting them from a varied diet of fruits and vegetables is clearly healthy, but high-dose antioxidant supplements have shown disappointing or even harmful results in some large studies. For most people, food is the safest and best source.
Capsules, tablets, softgels, powders, and foods (fruits, vegetables, nuts)
An interaction check asks whether these two react with each other — it does not ask whether Antioxidants is a good idea for someone in your situation. Here is what our Antioxidants record says about it on its own.
Antioxidants: dosing
There is no single "antioxidant dose" because the term covers many different nutrients and plant compounds. For vitamins and minerals, established recommended daily amounts and upper limits exist (set by health authorities), and exceeding the upper limit can be unsafe.The best general approach is to get antioxidants from a varied diet rather than pills.
From our Antioxidants monograph — the full record covers uses, side effects and every documented interaction.
About Progestin-Only (norethindrone) Oral Contraceptives
What Is Progestin-Only (norethindrone) Oral Contraceptives Used For?
Brand names: Ovrette, Orval 21
Norethindrone progestin-only pills — sometimes called the "mini-pill" — are used solely to prevent pregnancy. They do not contain estrogen, which makes them an option for women who cannot or prefer not to use estrogen-containing contraceptives.
When taken perfectly (same time every day, no missed pills), fewer than 1 in 100 women will become pregnant in the first year. With typical use, that number rises to about 9 in 100 — mostly because of late or skipped pills. Consistency is everything with this method.
Most-Reported Side Effects for Norgestrel
From FAERS, the FDA’s public side-effect reporting system (2,254 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Antioxidants
Browse every other medication we’ve checked against Antioxidants — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Antioxidants against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Antioxidants list.
Antioxidants References
The 1 references that drive our Antioxidants monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Tenório MB, Ferreira RC, Moura FA, Bueno NB, Goulart MOF, Oliveira ACM. Oral antioxidant therapy for prevention and treatment of preeclampsia: Meta-analysis of randomized controlled trials. Nutr Metab Cardiovasc Dis. 2018 Sep;28(9):865-876. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Norgestrel Is Linked to Lower Levels of 2 Nutrients
Natural Medicines records Norgestrel as a medicine that can lower these. This is not an interaction with Antioxidants — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Norgestrel nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Antioxidants and Norgestrel Together: Common Questions
Is it safe to take Antioxidants with Norgestrel?
Does Norgestrel interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Norgestrel and Antioxidants?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.