Drug & supplement interaction

Black Alder + Daprodustat

Daprodustat brand name: Jesduvroq.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Black Alder and Daprodustat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Black Alder and Daprodustat

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Daprodustat and Black Alder in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Black Alder safety at a glance

Black Alder overall Use caution Limited safety data exist and it may cause nausea or stomach upset, so use cautiously and briefly.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoiding it is the safer choice.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Daprodustat and Black Alder? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Daprodustat

Interactions in our licensed database are recorded against drug classes, not just single drug names. Daprodustat is filed under 2 classifications — cytochrome p450 2c8 (cyp2c8) substrates, oral drugs. Black Alder has documented interactions with 2 drug classes — the most serious being cisplatin (platinol-aq) (moderate) and doxorubicin (adriamycin, others) (moderate) — and none of Daprodustat’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Black Alder Does Interact With Other Medications

Black Alder has 2 moderate known drug interactions in our database — Daprodustat isn’t one of them. If you take anything else, check it against the full list below.

Moderate 2 No known interaction 2,828 (incl. Daprodustat)
Taking anything else?

Check Another of Your Medications Against Black Alder

Covers the 2,830 medications we’ve checked against Black Alder. Pick one to open its full report.

What to actually watch for

What Daprodustat’s Own FDA Label Lists

This is not an interaction — none of it involves Black Alder. These are the most notable effects listed in the ADVERSE REACTIONS section of Daprodustat’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 8 of them are worth acting on rather than waiting out — marked below.

  • Heart failure Worth acting on mentioned in 4.9% of FDA reports for Daprodustat
  • A heart attack Worth acting on
  • Blood clots Worth acting on
  • Kidney problems Worth acting on mentioned in 4.9% of FDA reports for Daprodustat
  • Anemia Worth acting on mentioned in 5.1% of FDA reports for Daprodustat
  • Raised blood pressure Worth acting on
  • Hives Worth acting on
  • An allergic reaction Worth acting on
  • Stomach upset
  • Stomach pain

Showing the 10 most notable of 12 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Daprodustat. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,756 voluntary FDA FAERS reports for Daprodustat that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Black Alder’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Black Alder side to compare — that is a limit of the record, not a statement that Black Alder has no side effects.

Everything else you take

See Every Supplement That Interacts With Daprodustat

This page covers Black Alder only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Daprodustat page lists 28 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), African Wild Potato (moderate), Breadfruit (moderate), Cannabidiol (cbd) (moderate) and Coffee Charcoal (moderate).

By severity: 1 major · 16 moderate · 11 minor.

From our pharmacist’s overview on the Daprodustat page

“People taking daprodustat (Jesduvroq) for anemia from chronic kidney disease are often the same people using fiber for constipation or CBD for sleep, and this interaction list deserves genuine care. Of the 28 supplement ingredients on file, eleven may block CYP2C8, the enzyme that clears daprodustat, which could raise its levels beyond…”

Reviewed by 2 · Jul 18, 2026

Open the Daprodustat interaction page

One more smart check

Taking Black Alder as Part of a Dietary Supplement Product? Check It for Interactions

We hold 21 real supplement products containing Black Alder, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Black Alder. Even though Black Alder itself has no known interaction with Daprodustat, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Black Alder and Daprodustat Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Black Alder
Top half

#590 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Daprodustat
Steady interest

#2,133 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Black Alder reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Black Alder and Daprodustat records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Black Alder

What is Black Alder?

Black Alder
  • Sore throat and mouth inflammation
  • Skin wounds and irritation (topical)
  • Fever and general aches (traditional)
  • Digestive complaints
  • Astringent for minor bleeding

Black Alder is a European tree whose bark and leaves have a long history in folk medicine, mainly as an astringent gargle or wound wash. There is very little modern human research to confirm any of these uses, and it can cause stomach upset, so it should be used cautiously and avoided during pregnancy and breastfeeding.

Alnus glutinosa · Betulaceae · Bark, leaves, and sometimes the catkins · Dried bark or leaf for tea, decoctions, tinctures, and gargles or mouth rinses

An interaction check asks whether these two react with each other — it does not ask whether Black Alder is a good idea for someone in your situation. Here is what our Black Alder record says about it on its own.

Black Alder: dosing

There is no established, standardized dose for Black Alder. Traditional use involved making a tea or decoction from the dried bark or leaves, or using a diluted preparation as a gargle or skin wash.If you choose to use a product, follow the directions on the label and do not exceed the recommended amount.

From our Black Alder monograph — the full record covers uses, side effects and every documented interaction.

Read the full Black Alder monograph & all interactions
Medication

About Daprodustat

What Is Daprodustat Used For?

Brand name: Jesduvroq

Jesduvroq (daprodustat) is approved to treat anemia due to chronic kidney disease (CKD) in adults who have been on dialysis for at least four months. It works by stimulating the body's own red blood cell production to reduce the need for blood transfusions.

Important limits: Jesduvroq is not a substitute for emergency blood transfusions, and it is not approved for people with CKD who are not on dialysis. It has also not been shown to improve quality of life, fatigue, or overall well-being.

Most-Reported Side Effects for Daprodustat

From FAERS, the FDA’s public side-effect reporting system (1,878 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hospitalisation 276 reports
Haemoglobin decreased 94 reports
Renal impairment 91 reports
Cardiac failure 86 reports
Haemoglobin increased 77 reports
See full Daprodustat drug information
Keep checking

Other Drugs & Black Alder

Browse every other medication we’ve checked against Black Alder — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
2Moderate
0Minor
2,827No known interaction
2 Moderate 2,827 No interaction
Moderate

2 interactions

No interaction 2,827 drugs checked — show the list

We also checked Black Alder against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,827 medications checked with no known interaction — see the full Black Alder list.

See the full Black Alder interactions page
See every supplement checked against Daprodustat, ranked by severity
Evidence & sources

Black Alder References

The 1 references that drive our Black Alder monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Dinic J, Novakovic M, Podolski-Renic A, et al. Antioxidative activity of diarylheptanoids from the bark of black alder (Alnus glutinosa) and their interaction with anticancer drugs. Planta Med 2014;80(13):1088-96. doi: 10.1055/s-0034-1382993. Epub 2014 Au PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Black Alder and Daprodustat Together: Common Questions

Is it safe to take Black Alder with Daprodustat?
We do not list a known interaction between Black Alder and Daprodustat. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Black Alder and Daprodustat combination checked?
Interactions in our licensed database are recorded against drug classes. Daprodustat is filed under 2 classifications, and Black Alder has documented interactions with 2 drug classes — none of Daprodustat's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Black Alder interact with any other medications?
Yes. Black Alder has 2 documented drug interactions in our database — Daprodustat is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Daprodustat interact with any supplements?
Yes. Daprodustat has documented interactions with 28 supplements in our database — Black Alder is not one of them. The Daprodustat interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Black Alder monograph Uses, safety profile, and every drug interaction in one place Daprodustat drug information The full plain-English guide to this medication Daprodustat supplement interactions Every supplement checked against Daprodustat, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Daprodustat and Black Alder?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.