Drug & supplement interaction

Blackberry + Crofelemer

Crofelemer brand names: Fulyzaq, Mytesi.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Blackberry and Crofelemer in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Blackberry and Crofelemer

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Crofelemer and Blackberry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Blackberry at all — not against Crofelemer, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Blackberry safety at a glance

Blackberry overall Generally safe The fruit is safe as a food; medicinal leaf and root preparations are likely safe in typical amounts but less studied.
Pregnancy Use caution The berry as food is fine, but concentrated leaf or root supplements lack safety data, so use caution.
Breastfeeding Use caution Eating the fruit is fine, but there is not enough information on medicinal supplements while nursing.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Crofelemer and Blackberry? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Crofelemer’s Own FDA Label Lists

This is not an interaction — none of it involves Blackberry. These are the most notable effects listed in the ADVERSE REACTIONS section of Crofelemer’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Yellowing of the skin or eyes Worth acting on
  • A higher chance of infection Worth acting on
  • Bloating or gas
  • Back pain
  • Cough
  • Joint pain
  • Muscle pain
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Crofelemer. Read the label on DailyMed › Where a percentage is shown, it is the share of 233 voluntary FDA FAERS reports for Crofelemer that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Blackberry’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Blackberry side to compare — that is a limit of the record, not a statement that Blackberry has no side effects.

Everything else you take

See Every Supplement That Interacts With Crofelemer

This page covers Blackberry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Crofelemer page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

Open the Crofelemer interaction page

One more smart check

Taking Blackberry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,648 real supplement products containing Blackberry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Blackberry. Even though Blackberry itself has no known interaction with Crofelemer, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Blackberry and Crofelemer Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Blackberry
Top 25%

#197 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Crofelemer
Steady interest

#2,581 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Blackberry is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Blackberry reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Blackberry and Crofelemer records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Blackberry

What is Blackberry?

  • Diarrhea
  • Sore throat and mouth rinse
  • General antioxidant support
  • Digestive upset
  • Source of vitamins and fiber

Blackberry is a common edible berry that is safe and nutritious as a food, rich in vitamin C, fiber, and antioxidant plant compounds. The leaves and root have a long history of traditional use for diarrhea and sore throat, but high-quality human studies on these medicinal uses are limited. Enjoy the fruit freely, but talk to your pharmacist or doctor before using concentrated leaf or root supplements.

Rubus fruticosus · Rosaceae · Fruit, leaves, and root · Fresh or frozen fruit, juice, tea (from dried leaves), capsules, extracts

An interaction check asks whether these two react with each other — it does not ask whether Blackberry is a good idea for someone in your situation. Here is what our Blackberry record says about it on its own.

Blackberry: dosing

There is no official standardized dose for blackberry as a supplement. As a food, blackberries can be eaten freely as part of a balanced diet.For leaf teas or extracts, traditional use varies and a reliable evidence-based dose has not been established. If you choose to use a blackberry supplement, follow the directions on the product label and do not exceed the recommended amount.

From our Blackberry monograph — the full record covers uses, side effects and every documented interaction.

Read the full Blackberry monograph & all interactions
Medication

About Crofelemer

What Is Crofelemer Used For?

Brand names: Fulyzaq, Mytesi

Mytesi (crofelemer) is approved to provide symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS who are taking antiretroviral therapy.

It is not intended to treat diarrhea caused by an infection. Before starting Mytesi, a doctor will rule out infectious causes of diarrhea.

Most-Reported Side Effects for Crofelemer

From FAERS, the FDA’s public side-effect reporting system (233 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 26 reports
Anxiety 14 reports
Emotional distress 14 reports
Anhedonia 12 reports
Fatigue 11 reports
See full Crofelemer drug information
Keep checking

Other Drugs & Blackberry

Browse every other medication we’ve checked against Blackberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Blackberry against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Blackberry list.

See the full Blackberry interactions page
See every supplement checked against Crofelemer, ranked by severity
Evidence & sources

Blackberry References

The 1 sources that drive our Blackberry monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Blackberry is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Antioxidants: In Depth — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Blackberry and Crofelemer Together: Common Questions

Is it safe to take Blackberry with Crofelemer?
We do not list a known interaction between Blackberry and Crofelemer. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Crofelemer interact with any supplements?
Yes. Crofelemer has documented interactions with 17 supplements in our database — Blackberry is not one of them. The Crofelemer interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Blackberry monograph Uses, safety profile, and every drug interaction in one place Crofelemer drug information The full plain-English guide to this medication Crofelemer supplement interactions Every supplement checked against Crofelemer, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Crofelemer and Blackberry?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.