Blackberry Drug Interactions, Uses, Safety & More
What is this page for?
First and foremost: how Blackberry interacts with medications. The heart of this page is the interaction list — every drug Blackberry is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Blackberry is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Blackberry against your medication
Add one medicationDrugs that interact with Blackberry
0 medications have a known interaction with Blackberry, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Blackberry. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Blackberry combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Blackberry: Uses, Safety & Side Effects
Blackberry is a common edible berry that is safe and nutritious as a food, rich in vitamin C, fiber, and antioxidant plant compounds. The leaves and root have a long history of traditional use for diarrhea and sore throat, but high-quality human studies on these medicinal uses are limited. Enjoy the fruit freely, but talk to your pharmacist or doctor before using concentrated leaf or root supplements.
- Scientific name
- Rubus fruticosus
- Family
- Rosaceae
- Part used
- Fruit, leaves, and root
- Common forms
- Fresh or frozen fruit, juice, tea (from dried leaves), capsules, extracts
- Diarrhea
- Sore throat and mouth rinse
- General antioxidant support
- Digestive upset
- Source of vitamins and fiber
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
The fruit is safe as a food; medicinal leaf and root preparations are likely safe in typical amounts but less studied.
Insufficient reliable information available; avoid using in amounts greater than those found in foods.
Read the full pregnancy detailInsufficient reliable information available; avoid using in amounts greater than those found in foods.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Blackberry is a dark purple-black berry that grows on a thorny shrub in the rose family. The plant is found wild and cultivated across Europe, North America, and many other temperate parts of the world, often along roadsides, fields, and hedgerows.
People mainly enjoy blackberries as a food. The fruit is eaten fresh or frozen and used in jams, juices, and desserts. Beyond food, traditional herbalists have used blackberry leaves and root to make teas and gargles. The fruit, leaves, and root all contain plant compounds called tannins and antioxidants that are behind many of their traditional uses.
Uses & effectiveness
Blackberry is best known and valued as a nutritious food. The fruit is a good source of vitamin C, fiber, vitamin K, manganese, and antioxidant pigments called anthocyanins.
Traditionally, blackberry leaf and root teas have been used for diarrhea and as a gargle for sore throats and mouth irritation. These uses are linked to the astringent tannins in the plant. However, modern human studies are limited, and we cannot say for sure how well blackberry works for these conditions.
Some laboratory and animal studies suggest blackberry compounds have antioxidant and antimicrobial activity, but this kind of research does not prove that eating blackberries or taking supplements will treat or prevent any disease in people. Overall, the evidence for medicinal benefits beyond basic nutrition is preliminary and weak.
How it works
Blackberries are rich in tannins, which are astringent compounds that can tighten and tone tissues. This astringent action is the traditional reason blackberry leaf or root is used for diarrhea and as a throat gargle.
The fruit also contains anthocyanins and other polyphenols, along with vitamin C. These act as antioxidants, meaning they may help protect cells from a type of damage called oxidative stress. The fiber in the fruit supports normal digestion.
It is important to know that most of these effects come from laboratory and animal studies. How well they translate into real health benefits for people is not well established.
Safety & precautions
Blackberry fruit is widely eaten and is considered safe as a food for most people. Medicinal preparations made from the leaves and root are also generally thought to be safe in typical amounts, but they have not been studied as carefully.
Because the leaves and root contain tannins, taking large amounts over a long time may cause stomach upset. People with known allergies to berries or to other plants in the rose family should be cautious.
For pregnancy, eating blackberries as a food is fine. However, there is not enough safety information about concentrated leaf or root supplements, so it is best to avoid those unless your doctor approves. The same caution applies while breastfeeding. As always, check with your pharmacist or doctor before starting any herbal supplement.
Side effects
Blackberry fruit rarely causes side effects when eaten in normal amounts. Eating very large quantities could cause mild stomach upset or loose stools due to the fiber.
Concentrated leaf or root products that are high in tannins may cause nausea or stomach irritation in some people. Allergic reactions are uncommon but possible. Stop using the product and seek medical care if you notice signs of an allergic reaction such as rash, swelling, or trouble breathing.
Dosing
There is no official standardized dose for blackberry as a supplement. As a food, blackberries can be eaten freely as part of a balanced diet.
For leaf teas or extracts, traditional use varies and a reliable evidence-based dose has not been established. If you choose to use a blackberry supplement, follow the directions on the product label and do not exceed the recommended amount. Because supplement quality varies, it is a good idea to choose a reputable brand and check with your pharmacist or doctor first.
Blackberry & Pregnancy
Blackberry & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 1 sources that drive our Blackberry monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.
- Antioxidants: In Depth — NIH NCCIH Source
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Brands that make products with Blackberry
346 brands in our database make a supplement containing Blackberry.
Supplement products with Blackberry
1,769 products in our database contain Blackberry. Open any to see its full ingredient list and every drug interaction we check.
Blackberry: Common Questions
Does Blackberry interact with prescription medications?
How are Blackberry interactions rated?
Is it safe to take Blackberry with my medications?
Where does this Blackberry interaction information come from?
What is Blackberry used for?
Are blackberries good for you?
Is it safe to take Blackberry supplements while pregnant?
Can Blackberry leaf tea help with diarrhea?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Blackberry
A rotating sample of real supplements in our database that list Blackberry — open any to see its full ingredients and every drug interaction we check.
- Power Reds Strawberry Kiwi by NuMedica
- Organic Greens by Amvilab
- Floravital Iron + Herbs by Floradix
- Digestive Probiotic Gummies by TRUNATURE
- Life Extension Mix Capsules by Life Extension
- Probiotic Daily Powder by Country Life Realfood Organics
- Ultimate Daily Nutrition by Country Life Realfood Organics
- Life Extension Mix Tablets by Life Extension
- NanoGreens10+ Probiotic Natural Green Apple Flavor by BioPharma Scientific
- Organic Plant Calcium by Garden of Life MyKind Organics
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