Herb & supplement monograph

Blackberry Drug Interactions, Uses, Safety & More

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Reviewed by licensed pharmacists Sourced from Natural Medicines
Interaction report

Drugs that interact with Blackberry

0 medications have a known interaction with Blackberry, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Blackberry. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Blackberry combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Blackberry: Uses, Safety & Side Effects

The bottom line

Blackberry is a common edible berry that is safe and nutritious as a food, rich in vitamin C, fiber, and antioxidant plant compounds. The leaves and root have a long history of traditional use for diarrhea and sore throat, but high-quality human studies on these medicinal uses are limited. Enjoy the fruit freely, but talk to your pharmacist or doctor before using concentrated leaf or root supplements.

Scientific name
Rubus fruticosus
Family
Rosaceae
Part used
Fruit, leaves, and root
Common forms
Fresh or frozen fruit, juice, tea (from dried leaves), capsules, extracts
People commonly use it for
  • Diarrhea
  • Sore throat and mouth rinse
  • General antioxidant support
  • Digestive upset
  • Source of vitamins and fiber

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLikely safe

The fruit is safe as a food; medicinal leaf and root preparations are likely safe in typical amounts but less studied.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using in amounts greater than those found in foods.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using in amounts greater than those found in foods.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Blackberry is a dark purple-black berry that grows on a thorny shrub in the rose family. The plant is found wild and cultivated across Europe, North America, and many other temperate parts of the world, often along roadsides, fields, and hedgerows.

People mainly enjoy blackberries as a food. The fruit is eaten fresh or frozen and used in jams, juices, and desserts. Beyond food, traditional herbalists have used blackberry leaves and root to make teas and gargles. The fruit, leaves, and root all contain plant compounds called tannins and antioxidants that are behind many of their traditional uses.

Uses & effectiveness

Blackberry is best known and valued as a nutritious food. The fruit is a good source of vitamin C, fiber, vitamin K, manganese, and antioxidant pigments called anthocyanins.

Traditionally, blackberry leaf and root teas have been used for diarrhea and as a gargle for sore throats and mouth irritation. These uses are linked to the astringent tannins in the plant. However, modern human studies are limited, and we cannot say for sure how well blackberry works for these conditions.

Some laboratory and animal studies suggest blackberry compounds have antioxidant and antimicrobial activity, but this kind of research does not prove that eating blackberries or taking supplements will treat or prevent any disease in people. Overall, the evidence for medicinal benefits beyond basic nutrition is preliminary and weak.

How it works

Blackberries are rich in tannins, which are astringent compounds that can tighten and tone tissues. This astringent action is the traditional reason blackberry leaf or root is used for diarrhea and as a throat gargle.

The fruit also contains anthocyanins and other polyphenols, along with vitamin C. These act as antioxidants, meaning they may help protect cells from a type of damage called oxidative stress. The fiber in the fruit supports normal digestion.

It is important to know that most of these effects come from laboratory and animal studies. How well they translate into real health benefits for people is not well established.

Safety & precautions

Blackberry fruit is widely eaten and is considered safe as a food for most people. Medicinal preparations made from the leaves and root are also generally thought to be safe in typical amounts, but they have not been studied as carefully.

Because the leaves and root contain tannins, taking large amounts over a long time may cause stomach upset. People with known allergies to berries or to other plants in the rose family should be cautious.

For pregnancy, eating blackberries as a food is fine. However, there is not enough safety information about concentrated leaf or root supplements, so it is best to avoid those unless your doctor approves. The same caution applies while breastfeeding. As always, check with your pharmacist or doctor before starting any herbal supplement.

Side effects

Blackberry fruit rarely causes side effects when eaten in normal amounts. Eating very large quantities could cause mild stomach upset or loose stools due to the fiber.

Concentrated leaf or root products that are high in tannins may cause nausea or stomach irritation in some people. Allergic reactions are uncommon but possible. Stop using the product and seek medical care if you notice signs of an allergic reaction such as rash, swelling, or trouble breathing.

Dosing

There is no official standardized dose for blackberry as a supplement. As a food, blackberries can be eaten freely as part of a balanced diet.

For leaf teas or extracts, traditional use varies and a reliable evidence-based dose has not been established. If you choose to use a blackberry supplement, follow the directions on the product label and do not exceed the recommended amount. Because supplement quality varies, it is a good idea to choose a reputable brand and check with your pharmacist or doctor first.

Pregnancy & Breastfeeding

Blackberry & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using in amounts greater than those found in foods.

Blackberry & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using in amounts greater than those found in foods.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 sources that drive our Blackberry monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.

  1. Antioxidants: In Depth — NIH NCCIH Source
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Product directory

Supplement products with Blackberry

1,769 products in our database contain Blackberry. Open any to see its full ingredient list and every drug interaction we check.

Blackberry Fruit Powder by TerraVita Premium Collection Powder 4 Ounce(s) View ingredients & interactions Blackberry Leaf 450 mg by TerraVita Premium Collection Capsule 100 Capsule(s) View ingredients & interactions Blackberry Leaf Powder by TerraVita Premium Collection Powder 1 Ounce(s) View ingredients & interactions Blackberry Leaf Powder by TerraVita Premium Collection Powder 4 Ounce(s) View ingredients & interactions Blackberry Mushroom Gummies by BeWell Market Gummy Or Jelly 30 Gummy(ies) · 7.4 Ounce(s) · 210 Gram(s) View ingredients & interactions Blackberry Powder by Eclectic Herb Powder 90 Gram(s) · 3.2 Ounce(s) View ingredients & interactions Blackberry Rubus armeniacus by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Blackberry Rubus armeniacus Alcohol Free by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Blackberry Rubus fruticosus by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Blackberry Rubus fruticosus Alcohol Free by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Blackberry Rubus fruticosus Sugar Free by Herbal Terra Liquid 2 Fluid Ounce(s) · 60 mL View ingredients & interactions Blend Cognitive Energy Lemon Berry Bomb by NorthBound Nutrition Powder 11.64 oz · 330 Gram(s) View ingredients & interactions Blend Cognitive Energy Texas Nectar by NorthBound Nutrition Powder 0.68 lbs · 309 Gram(s) View ingredients & interactions Blend Cognitive Energy Texas Nectar by NorthBound Nutrition Powder 11.64 oz · 330 Gram(s) View ingredients & interactions Blend Energy Raspberry Lemonade by NorthBound Nutrition Powder 0.82 lbs · 366 Gram(s) View ingredients & interactions Blue 1,000 mg Vitamin C Berry Blue by Emergen-C Powder 0.3 OZ/Packet · 8.4 G/Packet · 30 Packet(s) View ingredients & interactions Blue 1000 mg Vitamin C Triple Berry by Emergen-C Powder 0.3 oz. · 8.4 g View ingredients & interactions Blueberry Detox by Purity Products Powder 303 Gram(s) · 10.69 Ounce(s) View ingredients & interactions Blueberry Detox Caps by Purity Products Capsule 90 Capsule(s) View ingredients & interactions Bone Strength by Dr. Garber's Liquid 2 fl. Oz. · 60 mL View ingredients & interactions Boost by NaturesPlus BrainCeutix Capsule 90 Capsule(s) View ingredients & interactions BP Pack by Douglas Laboratories Other (e.g. Tea Bag) 30 Pack(s) View ingredients & interactions BP Pack by Douglas Laboratories Other (e.g. Tea Bag) 30 Pack(s) View ingredients & interactions Cardio Cuts 3.0 Peach Mango by NDS Powder 8.6 oz. · 244 Gram(s) View ingredients & interactions
Pharmacist Counseling Corner

Blackberry: Common Questions

Does Blackberry interact with prescription medications?
We do not currently list any known drug interactions for Blackberry. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Blackberry interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Blackberry with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Blackberry interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Blackberry used for?
Blackberry is mostly enjoyed as a nutritious fruit rich in vitamin C, fiber, and antioxidants. Traditionally, its leaves and root have been used as a tea for diarrhea and as a gargle for sore throats, though strong human evidence is limited.
Are blackberries good for you?
Yes. As a food, blackberries are a healthy choice that provides fiber, vitamin C, vitamin K, and antioxidant plant pigments. They fit well into a balanced diet.
Is it safe to take Blackberry supplements while pregnant?
Eating Blackberry fruit is fine during pregnancy. However, there is not enough safety data on concentrated leaf or root supplements, so it is best to avoid those unless your doctor approves.
Can Blackberry leaf tea help with diarrhea?
Blackberry leaf and root contain astringent tannins and have traditionally been used for diarrhea, but well-designed human studies are lacking. Check with your pharmacist or doctor if diarrhea is severe or lasts more than a couple of days.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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