Drug & supplement interaction

Blood Type Diet + Acyclovir

Acyclovir brand names: Zovirax, Zovirax Injection, Sitavig, Avaclyr.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Blood Type Diet and Acyclovir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Blood Type Diet and Acyclovir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Acyclovir and Blood Type Diet in our sources. This does not guarantee that the combination is completely free of risk — research on Blood Type Diet alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Blood Type Diet at all — not against Acyclovir, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Blood Type Diet is an eating pattern rather than something you take. Ask your pharmacist or doctor before changing how you eat while on a prescribed medicine: some medicines are dosed around meals, and a change in diet can change how they work. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Blood Type Diet safety at a glance

Blood Type Diet overall Use caution The diet itself is generally food-based, but restricting whole food groups may lead to nutrient gaps.
Pregnancy Use caution Restrictive eating plans may limit needed nutrients during pregnancy; check with your doctor first.
Breastfeeding Use caution Avoid overly restrictive versions while nursing and ensure adequate calories and nutrients.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Acyclovir and Blood Type Diet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Acyclovir’s Own FDA Label Lists

This is not an interaction — none of it involves Blood Type Diet. These are the most notable effects listed in the ADVERSE REACTIONS section of Acyclovir’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you follow Blood Type Diet and take the medicine. 4 of them are worth acting on rather than waiting out — marked below.

  • Low mood Worth acting on
  • Kidney problems Worth acting on
  • A higher chance of infection Worth acting on mentioned in 5.0% of FDA reports for Acyclovir
  • Bleeding or bruising Worth acting on
  • Joint pain
  • Tiredness mentioned in 7.0% of FDA reports for Acyclovir
  • Stomach pain
  • A skin rash mentioned in 3.7% of FDA reports for Acyclovir
  • Dizziness
  • Nausea mentioned in 4.9% of FDA reports for Acyclovir

Showing the 10 most notable of 12 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Acyclovir. Read the label on DailyMed › Where a percentage is shown, it is the share of 114,761 voluntary FDA FAERS reports for Acyclovir that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Blood Type Diet’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Blood Type Diet side to compare — that is a limit of the record, not a statement that Blood Type Diet has no side effects.

From our Q&A

Questions About Blood Type Diet or Acyclovir

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Blood Type Diet or Acyclovir, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Acyclovir

This page covers Blood Type Diet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Acyclovir page lists 37 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Siberian Cocklebur (major), African Wild Potato (moderate) and Aristolochia (moderate).

By severity: 3 major · 23 moderate · 11 minor.

From our pharmacist’s overview on the Acyclovir page

“Kidney strain is the risk to understand first. Acyclovir (Zovirax) can stress the kidneys on its own, and a few ingredients here, Siberian cocklebur especially, are toxic to kidney tissue, so pairing them could compound the harm.”

Reviewed by 2 · Jul 18, 2026

Open the Acyclovir interaction page

How much people look this up

Where Blood Type Diet and Acyclovir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Blood Type Diet
Steady interest

#1,363 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Acyclovir
Top 5%

#59 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Blood Type Diet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Blood Type Diet and Acyclovir records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Eating pattern

About Blood Type Diet

What is Blood Type Diet?

  • Weight loss
  • General wellness
  • Heart health
  • Digestive health
  • Reducing inflammation

The Blood Type Diet claims that eating foods matched to your ABO blood type improves health and weight, but good-quality studies have not shown that blood type determines who benefits from a given diet. Any health improvements people see are more likely from simply eating more whole, unprocessed foods. Talk to a pharmacist or doctor before making big changes, especially if you have a health condition.

Eating plan (whole-food diet based on ABO blood type)

An interaction check asks whether these two react with each other — it does not ask whether Blood Type Diet is a good idea for someone in your situation. Here is what our Blood Type Diet record says about it on its own.

Blood Type Diet: dosing

There is no "dose" for the Blood Type Diet — it is an eating pattern, not a pill. Followers are given food lists for their blood type and adjust meals accordingly.If you want to try it, focus on the healthy parts (more whole foods, fewer processed foods) and make sure you still get a full range of nutrients. A pharmacist, doctor, or registered dietitian can help you plan a balanced version and decide whether any supplement, such as a multivitamin, is needed.

From our Blood Type Diet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Blood Type Diet monograph & all interactions
Medication

About Acyclovir

What Is Acyclovir Used For?

Brand names: Zovirax, Zovirax Injection, Sitavig, Avaclyr

Acyclovir treats infections caused by herpes viruses. Depending on the form, it is used for cold sores (herpes labialis), genital herpes (initial episodes and recurrent flare-ups), shingles (herpes zoster), and chickenpox (varicella). It can also be used long-term to suppress recurrent genital herpes outbreaks.

Some forms are approved for more serious situations: acyclovir injection is used in hospital settings for herpes simplex encephalitis (herpes infection of the brain), neonatal herpes (in newborns), and herpes or shingles infections in immunocompromised patients. Avaclyr ophthalmic ointment is specifically indicated for acute herpetic keratitis (a herpes ulcer on the cornea of the eye). Sitavig buccal tablet and Zovirax cream are specifically indicated for recurrent cold sores in immunocompetent adults.

Most-Reported Side Effects for Acyclovir

From FAERS, the FDA’s public side-effect reporting system (114,761 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 8,029 reports
Diarrhea 7,348 reports
Pneumonia 5,700 reports
Nausea 5,643 reports
Fever 4,989 reports
See full Acyclovir drug information
Keep checking

Other Drugs & Blood Type Diet

Browse every other medication we’ve checked against Blood Type Diet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Blood Type Diet References

The 1 references that drive our Blood Type Diet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Barnard ND, Rembert E, Freeman A, Bradshaw M, Holubkov R, Kahleova H. Blood Type Is Not Associated with Changes in Cardiometabolic Outcomes in Response to a Plant-Based Dietary Intervention. J Acad Nutr Diet. 2020;S2212-2672(20)31197-7. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Following Blood Type Diet While Taking Acyclovir: Common Questions

Is it safe to follow Blood Type Diet while taking Acyclovir?
We do not list a known interaction between Blood Type Diet and Acyclovir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Acyclovir interact with any supplements?
Yes. Acyclovir has documented interactions with 37 supplements in our database — Blood Type Diet is not one of them. The Acyclovir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Acyclovir and Blood Type Diet?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.