Boswellia Serrata - Dupixent (Dupilumab) Interaction

Interaction Details

Pharmacist Analysis

No interaction has been noted between Boswellia and the drug in question on this interaction check.

In terms of other interactions, Boswellia serrata has been shown in laboratory studies to mildly inhibit several enzymes involved in drug metabolism, including CYP1A2, CYP2C19, CYP2C9, CYP2D6, and CYP3A4. This inhibition may increase the levels of drugs metabolized by these enzymes, potentially leading to adverse effects.

However, it is important to note that this inhibition has only been seen in a lab setting, and has not been reported in humans. Whether or not Boswellia supplements have clinically significant drug interactions due to the effects on the above enzymes isn't well known. In most cases, it appears unlikely that these interactions would be clinically significant as there is a lack of reports of problems being caused in humans.

In addition, Boswellia serrata may interact with immunosuppressive drugs. 

Studies show that Boswellia may help reduce the activity of some cells involved in autoimmune diseases. This could lead to a decrease in the production of antibodies and certain immune cells. However, other studies have found that certain components of Boswellia serrata may actually stimulate the immune system in certain situations. More research is needed to better understand the effect of Boswellia on immunosuppressive drugs.

Dupilumab Overview

• Dupilumab injection is used to treat the symptoms of eczema (atopic dermatitis; a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes) in adults and children 6 months of age and older who cannot use other medications for their condition or whose eczema has not responded to other medications. It is also used along with other medications to prevent wheezing, shortness of breath, coughing, and chest tightness due to certain types of asthma in adults and children 6 years and older whose symptoms are not controlled with other medications. Dupilumab injection is also used along with other medications to treat chronic rhinosinusitis with nasal polyposis (ongoing runny nose, sinus swelling and/or nasal congestion, with or without a reduced sense of smell or pain and pressure in the face) in adults whose symptoms are not controlled with other medications. It is also used to treat eosinophilic esophagitis (EoE; a condition that involves high levels of blood cells in the esophagus [tube that connects the mouth to the stomach] that may damage tissues of the esophagus) in adults and children 12 years of age and older who weigh at least 88 pounds (40 kg). Dupilumab injection is also used to treat prurigo nodularis (a skin condition that causes crusty lumps on the skin and severe itching) in adults. Dupilumab injection is in a class of medications called monoclonal antibodies. It works by stopping the action of certain substances in the body that cause inflammation.

Boswellia Serrata - More Interactions

Boswellia Serrata interacts with 922 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.