Collagen Type I (native) + Raltegravir
Raltegravir brand name: Isentress.
We found no known interaction between Collagen Type I (native) and Raltegravir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Collagen Type I (native) and Raltegravir
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Raltegravir and Collagen Type I (native) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Collagen Type I (native) at all — not against Raltegravir, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Collagen Type I (native) safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Raltegravir
This page covers Collagen Type I (native) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Raltegravir page lists 33 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Breadfruit (moderate), Brussels Sprout (moderate), Cabbage (moderate) and Calcium (moderate).
By severity: 1 major · 22 moderate · 10 minor.
From our pharmacist’s overview on the Raltegravir page
“For someone taking raltegravir (Isentress) to keep HIV suppressed, a steady drug level is what blocks rebound and resistance, and this list deserves genuine vigilance. The lone major-rated entry is activated charcoal, which can soak up the medicine in the gut and cut what reaches your blood.”
Reviewed by 2 · Jul 18, 2026
Where Collagen Type I (native) and Raltegravir Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,277 of 1,452 supplements looked up here in the last 7 days
#2,481 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Collagen Type I (native) reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Collagen Type I (native) and Raltegravir records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Collagen Type I (native)
What is Collagen Type I (native)?
- Skin health and wrinkles
- Joint comfort and arthritis
- Bone strength
- Hair and nail support
- Wound and tissue repair
Type I collagen is the most abundant protein in human skin, bones, and tendons, and it is sold as a supplement to support skin, joints, and bones. 'Native' (undenatured) Type I collagen keeps its natural triple-helix structure rather than being broken down into peptides. Early research is promising for skin and joints, but evidence is still limited, and most products are generally well tolerated.
Skin, bones, tendons, scales, and connective tissue of cows, pigs, fish, or chicken · Powders, capsules, drinks, and undenatured (native) collagen tablets
An interaction check asks whether these two react with each other — it does not ask whether Collagen Type I (native) is a good idea for someone in your situation. Here is what our Collagen Type I (native) record says about it on its own.
Collagen Type I (native): dosing
There is no official standardized dose for native Type I collagen, and the right amount depends on the specific product. Doses used in studies vary widely depending on the form (powder versus tablet) and whether the collagen is native or hydrolyzed.The safest approach is to follow the directions on the product label and not exceed them.
From our Collagen Type I (native) monograph — the full record covers uses, side effects and every documented interaction.
About Raltegravir
What Is Raltegravir Used For?
Brand name: Isentress
Raltegravir — available as Isentress and as the generic raltegravir tablet — is used to treat HIV-1 (human immunodeficiency virus) infection. It is always used together with other antiretroviral (anti-HIV) medicines, never on its own.
Isentress is approved for adults and for children weighing at least 2 kg. Raltegravir tablets are approved for adults and for children weighing at least 25 kg who can swallow a tablet whole.
Most-Reported Side Effects for Raltegravir
From FAERS, the FDA’s public side-effect reporting system (16,418 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Collagen Type I (native)
Browse every other medication we’ve checked against Collagen Type I (native) — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Collagen Type I (native) against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Aspirin ›
- Abemaciclib ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Warfarin Sodium ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Amitriptyline ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Collagen Type I (native) list.
Collagen Type I (native) References
The 1 references that drive our Collagen Type I (native) monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Stancík R, Zvarka J, Hlavác M, Kubinec V, Rovenský J. Collagen type I in the treatment of painful osteoarthritis of the knee. Reumatologia. 2012;50(5):390-6. DOI
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Collagen Type I (native) and Raltegravir Together: Common Questions
Is it safe to take Collagen Type I (native) with Raltegravir?
Does Raltegravir interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.