Coriander - Aspirin, Codeine Phosphate, Methocarbamol Interaction
Herbal: Coriander
Also Known As: Coriandrum sativum, Coriander Essential Oil, Coriandre, Coriandri Fructus, Dhanyaka, Huile Essentielle de Coriandre, Koriander, Kustumburi
Drug: Aspirin, Codeine Phosphate, Methocarbamol
Brand names:
Robaxisal C
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
Aspirin, Codeine Phosphate, Methocarbamol is classified as belonging to the following category: Cns Depressants
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Evidence from animal research suggests that coriander fruit extract has sedative effects.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Emamghoreishi, M., Khasaki, M., and Aazam, M. F. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol. 1-15-2005;96(3):365-370.
Coriander Overview
Coriander, also known as cilantro, is an herb in the Apiaceae family. Both the fruit (seed) and leaves of the coriander plant are used in food as a spice and in traditional medicine. It is native to the Mediterranean region and is widely cultivated in many parts of the world. When used as medicine, coriander is most often used for gastrointestinal problems, including dyspepsia, nausea, diarrhea, flatulence, constipation, irritable bowel syndrome (IBS), and to stimulate the appetite. Coriander, when used topically, is also thought to have antimicrobial effects.
Coriander - More Interactions
Coriander interacts with 709 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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