Drug & supplement interaction

Cotton + Mirikizumab-mrkz

Mirikizumab-mrkz brand name: Omvoh.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Cotton and Mirikizumab-mrkz in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Cotton and Mirikizumab-mrkz

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mirikizumab-mrkz and Cotton in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Cotton at all — not against Mirikizumab-mrkz, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cotton safety at a glance

Cotton overall Use caution Cottonseed and root contain gossypol, which can be toxic in higher amounts; medicinal use is not well studied.
Pregnancy Likely Unsafe When used orally because it is a possible abortifacient and uterine stimulant. Read the full pregnancy detail
Breastfeeding Avoid Safety is unknown and gossypol may pass risks to the infant, so avoid while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mirikizumab-mrkz and Cotton? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Mirikizumab-mrkz’s Own FDA Label Lists

This is not an interaction — none of it involves Cotton. These are the most notable effects listed in the ADVERSE REACTIONS section of Mirikizumab-mrkz’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 5 of them are worth acting on rather than waiting out — marked below.

  • Yellowing of the skin or eyes Worth acting on
  • Hives Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Migraine
  • A stuffy or runny nose
  • Sore throat
  • Joint pain
  • Itching

Showing the 10 most notable of 12 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Mirikizumab-mrkz. Read the label on DailyMed › Cotton’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Cotton side to compare — that is a limit of the record, not a statement that Cotton has no side effects.

Special populations

Cotton in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally because it is a possible abortifacient and uterine stimulant.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Mirikizumab-mrkz

This page covers Cotton only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mirikizumab-mrkz page lists 89 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Active Hexose Correlated Compound (ahcc) (moderate) and Alfalfa (moderate).

By severity: 3 major · 85 moderate · 1 minor.

From our pharmacist’s overview on the Mirikizumab-mrkz page

“Mirikizumab (Omvoh) treats inflammatory bowel disease by dialing down part of the immune system, and its interaction list deserves genuine wariness, most of all around the liver. The three most serious entries, Siberian cocklebur plus beer and wine, all raise the odds of liver damage when combined with a medication that can stress the…”

Reviewed by 2 · Jul 18, 2026

Open the Mirikizumab-mrkz interaction page

One more smart check

Taking Cotton as Part of a Dietary Supplement Product? Check It for Interactions

We hold 8 real supplement products containing Cotton, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Cotton. Even though Cotton itself has no known interaction with Mirikizumab-mrkz, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Cotton and Mirikizumab-mrkz Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cotton
Steady interest

#960 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mirikizumab-mrkz
Top half

#1,117 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cotton reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Cotton and Mirikizumab-mrkz records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cotton

What is Cotton?

  • Menstrual cramps and bringing on menses
  • Cooking oil (cottonseed oil)
  • Traditional use as a contraceptive (gossypol)
  • Breast milk flow (traditional)
  • Skin and wound care (folk use)

Cotton is best known as a fiber and food-oil crop, but its root bark and seed have a long history in folk medicine for menstrual and reproductive complaints. Its seed pigment, gossypol, was studied as a male contraceptive but proved too toxic, and there is no good evidence that cotton supplements are safe or effective for any health condition. Talk to a pharmacist or doctor before using any cotton-derived product medicinally.

Gossypium hirsutum · Malvaceae · Root bark, seed, and seed oil (cottonseed oil) · Cottonseed oil, root bark extract/tincture, capsules

An interaction check asks whether these two react with each other — it does not ask whether Cotton is a good idea for someone in your situation. Here is what our Cotton record says about it on its own.

Cotton: dosing

There is no established safe or effective dose for cotton as a dietary supplement. Do not try to make your own preparations from cotton plant material.

From our Cotton monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cotton monograph & all interactions
Medication

About Mirikizumab-Mrkz

What Is Mirikizumab-Mrkz Used For?

Brand name: Omvoh

Omvoh (mirikizumab-mrkz) is used to treat moderately to severely active ulcerative colitis in adults — a condition where the large intestine becomes chronically inflamed and ulcerated. It is also used to treat moderately to severely active Crohn's disease in adults, another form of inflammatory bowel disease that can affect any part of the digestive tract.

Both uses are specific to Omvoh administered by injection — first as intravenous (into the vein) infusions to start treatment, then as subcutaneous (under the skin) injections for ongoing maintenance.

See full Mirikizumab-Mrkz drug information
Keep checking

Other Drugs & Cotton

Browse every other medication we’ve checked against Cotton — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Cotton References

The 2 references that drive our Cotton monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Ankrah, N. A., Nyarko, A. K., Addo, P. G., Ofosuhene, M., Dzokoto, C., Marley, E., Addae, M. M., and Ekuban, F. A. Evaluation of efficacy and safety of a herbal medicine used for the treatment of malaria. Phytother.Res 2003;17(6):697-701. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Cotton and Mirikizumab-mrkz Together: Common Questions

Is it safe to take Cotton with Mirikizumab-mrkz?
We do not list a known interaction between Cotton and Mirikizumab-mrkz. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Mirikizumab-mrkz interact with any supplements?
Yes. Mirikizumab-mrkz has documented interactions with 89 supplements in our database — Cotton is not one of them. The Mirikizumab-mrkz interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Mirikizumab-mrkz and Cotton?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.