Drug & supplement interaction

Elm Bark + Acamprosate

Acamprosate brand name: Campral.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated June 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Elm Bark and Acamprosate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Elm Bark and Acamprosate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Acamprosate and Elm Bark in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Elm Bark at all — not against Acamprosate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Elm Bark safety at a glance

Elm Bark overall Use caution Likely low-risk for short-term use in healthy adults, but human safety data are limited.

Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.

Breastfeeding Avoid No reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Acamprosate and Elm Bark? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

What to actually watch for

What Acamprosate’s Own FDA Label Lists

This is not an interaction — none of it involves Elm Bark. These are the most notable effects listed in the ADVERSE REACTIONS section of Acamprosate’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

A change in thyroid levels Worth acting on
Dependence or withdrawal symptoms Worth acting on
Thoughts of self-harm Worth acting on
Hearing loss Worth acting on
Bone thinning Worth acting on
Muscle weakness Worth acting on
Memory problems Worth acting on
Trouble swallowing Worth acting on
Bleeding in the gut Worth acting on
Low sodium Worth acting on

Showing the 10 most notable of 80 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Acamprosate. Read the label on DailyMed › Elm Bark’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Elm Bark side to compare — that is a limit of the record, not a statement that Elm Bark has no side effects.

Everything else you take

See Every Supplement That Interacts With Acamprosate

This page covers Elm Bark only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Acamprosate page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Acamprosate page

“Acamprosate (Campral) helps people stay off alcohol, and it only works if enough of it actually reaches your bloodstream. That is precisely what the supplements on this page can undermine.”

Reviewed by 2 · Jul 18, 2026

Open the Acamprosate interaction page

How much people look this up

Where Elm Bark and Acamprosate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Elm Bark

Steady interest

#1,358 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Acamprosate

Steady interest

#2,339 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Elm Bark is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Elm Bark reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Elm Bark and Acamprosate records this page draws on were last updated June 22, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Elm Bark

What is Elm Bark?

Diarrhea
Gastritis and stomach upset
Mild inflammation
Skin irritation
Sore throat

Elm bark (from Ulmus minor) has a long history in traditional medicine for digestive complaints and minor inflammation, but high-quality human studies are lacking, so its true effectiveness is unknown. It is generally considered low-risk for short-term use in adults, but it should not be confused with slippery elm (Ulmus rubra). Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have a health condition.

Ulmus minor · Ulmaceae · Bark · Dried bark, powder, tea, tincture/liquid extract, capsules

An interaction check asks whether these two react with each other — it does not ask whether Elm Bark is a good idea for someone in your situation. Here is what our Elm Bark record says about it on its own.

Elm Bark: dosing

There is no well-established standard dose for elm bark. Because human studies are lacking, no reliable, evidence-based amount has been set.If you use a commercial product, follow the directions on the label and do not exceed the recommended amount. Use it for short periods only, and stop if you have any unwanted effects.

From our Elm Bark monograph — the full record covers uses, side effects and every documented interaction.

Read the full Elm Bark monograph & all interactions

Medication

About Acamprosate

What Is Acamprosate Used For?

Brand name: Campral

Acamprosate Calcium delayed-release tablets are used to help people with alcohol dependence maintain abstinence — meaning they are used to support staying sober, not to help someone stop drinking in the first place. The medication is started after a person has already gone through alcohol withdrawal and is alcohol-free.

Acamprosate Calcium delayed-release tablets are meant to be part of a broader treatment plan that includes counseling and other psychosocial support. They have not been shown to be effective in people who have not yet detoxed or achieved abstinence before starting treatment.

See full Acamprosate drug information

Keep checking

Other Drugs & Elm Bark

Browse every other medication we’ve checked against Elm Bark — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

0Moderate

0Minor

2,829No known interaction

2,829 No interaction

No interaction 2,829 drugs checked — show the list

We also checked Elm Bark against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Elm Bark list.

See the full Elm Bark interactions page

See every supplement checked against Acamprosate, ranked by severity

Evidence & sources

Elm Bark References

The 2 sources that drive our Elm Bark monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Elm Bark is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

Slippery Elm — MedlinePlus (NIH) Source
Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Elm Bark and Acamprosate Together: Common Questions

Is it safe to take Elm Bark with Acamprosate?

We do not list a known interaction between Elm Bark and Acamprosate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Does Acamprosate interact with any supplements?

Yes. Acamprosate has documented interactions with 17 supplements in our database — Elm Bark is not one of them. The Acamprosate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Elm Bark monograph Uses, safety profile, and every drug interaction in one place Acamprosate drug information The full plain-English guide to this medication Acamprosate supplement interactions Every supplement checked against Acamprosate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Acamprosate and Elm Bark?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.