Germander + Sodium Sulfacetamide, Witch Hazel (orescription drug)
Sodium Sulfacetamide, Witch Hazel (orescription drug) brand name: Plexion SCT cream.
We found no known interaction between Germander and Sodium Sulfacetamide, Witch Hazel (orescription drug) in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Germander and Sodium Sulfacetamide, Witch Hazel (orescription drug)
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Sodium Sulfacetamide, Witch Hazel (orescription drug) and Germander in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Germander at all — not against Sodium Sulfacetamide, Witch Hazel (orescription drug), and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Germander safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Germander in Pregnancy & Breastfeeding
When used orally.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Sodium Sulfacetamide, Witch Hazel (orescription drug)
This page covers Germander only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sodium Sulfacetamide, Witch Hazel (orescription drug) page lists 3 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).
By severity: 2 moderate · 1 minor.
From our pharmacist’s overview on the Sodium Sulfacetamide, Witch Hazel (orescription drug) page
“Plexion SCT, the prescription cream that pairs sodium sulfacetamide with witch hazel for acne and rosacea, works at the skin surface, so its supplement interactions are about skin too. Just three ingredients are on file, none rated major, and this is a workable list for most people provided they know which combinations to watch.”
Reviewed by 2 · Jul 18, 2026
Open the Sodium Sulfacetamide, Witch Hazel (orescription drug) interaction page
Where Germander and Sodium Sulfacetamide, Witch Hazel (orescription drug) Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#846 of 1,452 supplements looked up here in the last 7 days
#2,181 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Germander reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Germander and Sodium Sulfacetamide, Witch Hazel (orescription drug) records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Germander
What is Germander?
- Weight loss aids
- Digestive complaints
- Appetite stimulation
- Gout and arthritis (traditional)
- Fever and infections (traditional)
Germander is a traditional herb that was once used for weight loss and digestion, but it has been linked to serious and sometimes fatal liver damage. Because of these well-documented liver risks, germander has been banned or restricted in several countries, and we strongly advise against using it.
Teucrium chamaedrys · Lamiaceae · Above-ground parts (leaves and flowering tops) · Tea, capsules, tinctures, dried herb
An interaction check asks whether these two react with each other — it does not ask whether Germander is a good idea for someone in your situation. Here is what our Germander record says about it on its own.
Germander: dosing
There is no safe or established dose for germander. A safer, evidence-based option is almost always available.
From our Germander monograph — the full record covers uses, side effects and every documented interaction.
Other Drugs & Germander
Browse every other medication we’ve checked against Germander — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Germander against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Amlodipine ›
- Levothyroxine ›
- Methylphenidate ›
- Warfarin ›
- Abemaciclib ›
- Ivermectin ›
- Testosterone ›
- Sertraline ›
- Acetaminophen ›
- Losartan Potassium ›
- Aspirin ›
- Rosuvastatin ›
- Metoprolol ›
- Escitalopram ›
- Clopidogrel ›
- Rivaroxaban ›
- Atorvastatin ›
- Methamphetamine ›
- Tirzepatide ›
- Docusate ›
- Ibuprofen ›
- Warfarin Sodium ›
- Sumatriptan ›
- Isotretinoin ›
- Valacyclovir ›
- Tadalafil ›
- Hydroxyurea ›
- Amlodipine Besylate ›
- Prednisone ›
- Semaglutide ›
- Metformin ›
- Lisdexamfetamine ›
- Propranolol ›
- Amitriptyline ›
- Amphetamine ›
- Methotrexate ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Fluoxetine ›
- Doxycycline ›
- Bendamustine ›
- Levothyroxine, Liothyronine ›
- Pregabalin ›
- Azithromycin ›
- Acyclovir ›
- Lamotrigine ›
- Gabapentin ›
- Dextroamphetamine ›
- Naproxen ›
- Quetiapine ›
- Clonazepam ›
- Buspirone ›
- Omeprazole ›
- Duloxetine ›
- Acetaminophen, Codeine ›
- Letrozole ›
- Citalopram ›
- Methylene Blue ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Germander list.
Germander References
The 5 references that drive our Germander monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Bruneton J. Pharmacognosy, Phytochemistry, Medicinal Plants. Paris: Lavoisier Publishing, 1995. DOI
- Larrey D, Vial T, Pauwels A, et al. Hepatitis after germander (Teucrium chamaedrys) administration: another instance of herbal medicine hepatotoxicity. Ann Intern Med 1992;117:129-32.
- Pauwels A, Thierman-Duffaud D, Azanowsky JM, et al. [Acute hepatitis caused by wild germander. Hepatotoxicity of herbal remedies. Two cases]. Gastroenterol Clin Biol 1992;16:92-5.
- Castot A, Djezzar S, Deleau N, et al. [Pharmacovigilance off the beaten track: herbal surveillance or pharmacovigilance of medicinal plants]. Therapie 1997;52:97-103.
- Mostefa-Kara N, Pauwels A, Pines E, et al. Fatal hepatitis after herbal tea. Lancet 1992;340:674. DOI
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Germander and Sodium Sulfacetamide, Witch Hazel (orescription drug) Together: Common Questions
Is it safe to take Germander with Sodium Sulfacetamide, Witch Hazel (orescription drug)?
Does Sodium Sulfacetamide, Witch Hazel (orescription drug) interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Sodium Sulfacetamide, Witch Hazel (orescription drug) and Germander?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.