Goli Apple Cider Vinegar Gummies - Orkambi (Ivacaftor, Lumacaftor) Interaction
Herbal: Goli Apple Cider Vinegar Gummies
Also Known As: Apple cider vinegar, ACV
Drug: Ivacaftor, Lumacaftor
Brand names:
Orkambi
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
There were no interactions found between Ivacaftor, Lumacaftor and Goli Apple Cider Vinegar Gummies. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pharmacist Analysis
The use of apple cider vinegar or the amounts of ACV in supplements is unlikely to cause clinically significant drug interactions at recommended dosages.
However, it is important to be aware of potential interactions, especially with medications that lower blood glucose levels, as these interactions have been theoretically proposed, but as I've written in my analysis on individual interaction detail pages, even this interaction is unlikely to be clinically significant for most.
In terms of side effects, it is uncommon for individuals to experience any adverse effects from taking ACV, but some mild side effects, such as nausea and indigestion, have been reported. It is important to consider that these side effects could be additive if taken with other medications that cause similar symptoms.
As always, it is important to consult with a healthcare provider before starting any new supplement, including ACV, to ensure its safe and appropriate use for your specific medical situation.
As Goli Apple Cider Vinegar gummies may have a mild blood sugar lowering effect, they should be used cautiously with antidiabetics like metformin, even though the risk of a clinically significant drug interaction is low.
- Dr. Brian Staiger, PharmDGoli Apple Cider Vinegar Gummies Overview
Goli ACV (apple cider vinegar) is a product manufactured by Goli Nutrition. Its main ingredient is apple cider vinegar, which is the fermented juice of crushed apples. The main component of apple cider vinegar is acetic acid, but it also contains small amounts of other organic acids, such as malic acid and citric acid, as well as water and trace minerals and vitamins, such as potassium, magnesium, calcium, and vitamins B1, B2, and B6. Goli ACV, in addition to apple cider vinegar, contains a blend of other ingredients, such as beetroot and pomegranate. It is marketed as a dietary supplement helping to support energy metabolism, a healthy immune system, heart health, and overall well-being. Each gummy contains 500mg of apple cider vinegar.
Ivacaftor, Lumacaftor Overview
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Lumacaftor and ivacaftor is used to treat certain types of cystic fibrosis (an inborn disease that causes problems with breathing, digestion, and reproduction) in adults and children 1 year of age and older. Lumacaftor is in a class of medications called cystic fibrosis transmembrane conductance regulator (CFTR) correctors. Ivacaftor is in a class of medications called cystic fibrosis transmembrane conductance regulator (CFTR) potentiators. Both of these medications work by improving the function of a protein in the body to decrease the build-up of thick mucus in the lungs and improving other symptoms of cystic fibrosis.
Goli Apple Cider Vinegar Gummies - More Interactions
Goli Apple Cider Vinegar Gummies interacts with 85 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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