Henna + Deferiprone
Deferiprone brand name: Ferriprox.
We found no known interaction between Henna and Deferiprone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Deferiprone states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Henna and Deferiprone
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Deferiprone and Henna in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Henna safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Deferiprone
Interactions in our licensed database are recorded against drug classes, not just single drug names. Deferiprone is filed under a single classification — oral drugs. Henna has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Deferiprone’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Henna Does Interact With Other Medications
Henna has 1 moderate known drug interaction in our database — Deferiprone isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Henna
We haven’t checked that one against Henna yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Henna. Pick one to open its full report.
Henna in Pregnancy & Breastfeeding
When used orally. Henna is believed to have abortifacient properties. There is insufficient reliable information available about the safety of henna when used topically; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Some Deferiprone Products Have a Food Rule — Henna Should Not Break It
At least one FDA label for a product containing Deferiprone says to take it with food. If you take Henna on an empty stomach out of habit, keep them separate — and take Deferiprone with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Deferiprone products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Recommended Dosage for 1,000 mg FERRIPROX T ablets ( twice a day) for Adult and Pediatric Patients with Transfusional Iron Overload due to Thalassemia Syndromes, Sickle Cell Disease or Other Anemias Starting Dos ag e for T wice a Day Tablets The recommended starting oral dosage of FERRIPROX Tablets (twice a day) is 75 mg/kg/day (actual body weight) in two divided doses per day (taken approxima
From the Dosage and Administration section of the FDA label we read for Deferiprone — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Deferiprone
This page covers Henna only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Deferiprone page lists 17 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).
By severity: 1 major · 7 moderate · 9 minor.
From our pharmacist’s overview on the Deferiprone page
“Deferiprone (Ferriprox) pulls excess iron out of the body in conditions like thalassemia, and that job depends on the pill actually being absorbed. Every one of the 17 supplements flagged against it threatens that step, which is why this list warrants real vigilance rather than a shrug.”
Reviewed by 2 · Jul 18, 2026
Taking Henna as Part of a Dietary Supplement Product? Check It for Interactions
We hold 9 real supplement products containing Henna, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Henna. Even though Henna itself has no known interaction with Deferiprone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Henna and Deferiprone Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#865 of 1,452 supplements looked up here in the last 7 days
#665 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Henna reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Henna and Deferiprone records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Henna
What is Henna?
- Hair and skin dye
- Cooling and skin care
- Wound and skin healing (traditional)
- Antimicrobial and antifungal (traditional)
- Nail and scalp conditions
Henna is a plant most widely used as a natural dye for hair, skin, and nails, and has a long history in traditional medicine for skin and minor wound care. Strong human evidence for medicinal benefits is limited, and pure (natural) henna applied to skin is generally well tolerated, but so-called 'black henna' products can cause serious skin reactions. Talk to a pharmacist or doctor before using henna for any health purpose, and avoid taking it by mouth.
Lawsonia inermis · Lythraceae · Leaves (also bark, seeds, and flowers in traditional use) · Dried leaf powder, paste, oil, and occasionally extracts; mostly used topically for hair and skin
An interaction check asks whether these two react with each other — it does not ask whether Henna is a good idea for someone in your situation. Here is what our Henna record says about it on its own.
Henna: dosing
There is no established medicinal dose for henna. It is mainly used externally as a paste or powder for dyeing hair, skin, and nails, and the amount used depends on the cosmetic purpose.If you choose to use a henna product, follow the directions on the label and choose pure, natural henna from a reputable source. Avoid products labeled or sold as 'black henna' because of the risk of serious reactions.Henna should not be taken by mouth.
From our Henna monograph — the full record covers uses, side effects and every documented interaction.
About Deferiprone
What Is Deferiprone Used For?
Brand name: Ferriprox
Deferiprone is used to remove excess iron that builds up in the body from repeated blood transfusions — a condition called transfusional iron overload. Too much iron in the body can damage organs over time, so deferiprone works to capture and remove it.
Ferriprox oral solution is approved for adults and children 3 years and older with thalassemia syndromes, sickle cell disease, or other anemias. Ferriprox tablets are approved for adults and children 8 years and older with the same conditions. Deferiprone tablets (generic) are approved for adult patients with thalassemia syndromes when their current iron-removal treatment is not working well enough.
Most-Reported Side Effects for Deferiprone
From FAERS, the FDA’s public side-effect reporting system (3,004 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Henna
Browse every other medication we’ve checked against Henna — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
1 interaction
No interaction 2,828 drugs checked — show the list
We also checked Henna against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Methylphenidate ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Metoprolol ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Lisinopril ›
- Amoxicillin ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Henna list.
Henna References
The 30 references that drive our Henna monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Lyon MJ, Shaw JC. Allergic contact dermatitis reaction to henna. Arch Dermatol 2000;136:124-5. PubMed
- Garcia Ortiz JC, Terron M, Bellido J. Contact allergy to henna. Int Arch Allergy Immunol 1997;114:298-9. PubMed
- Kandil HH, al-Ghanem MM, Sarwat MA, al-Thallab FS. Henna (Lawsonia inermis Linn.) inducing haemolysis among G6PD-deficient newborns. A new clinical observation. Ann Trop Paediatr 1996;16:287-91. PubMed
- Majoie IM, Bruynzeel DP. Occupational immediate-type hypersensitivity to henna in a hairdresser. Am J Contact Dermat 1996;7:38-40. DOI
- Lewin PK. Temporary henna tattoo with permanent scarification. CMAJ 1999;160:310.
- Lestringant GG, Bener A, Frossard PM. Cutaneous reactions to henna and associated additives. Br J Dermatol 1999;141:598-600. PubMed
- Etienne A, Piletta P, Hauser C, Pasche-Koo F. Ectopic contact dermatitis from henna. Contact Dermatitis 1997;:183. PubMed
- Wantke F, Gotz M, Jarisch R. Contact dermatitis due to henna, solvent red 1 and solvent red 3, a case report. Contact Dermatitis 1992;27:346-7. PubMed
- Nigam PK, Saxena AK. Allergic contact dermatitis from henna. Contact Dermatitis 1988;18:55-6. PubMed
- Gupta BN, Mathur AK, Agarwal C, Singh A. Contact sensitivity to henna. Contact Dermatitis 1986;15:303-4. PubMed
- Pasricha JS, Gupta R, Panjwani S. Contact dermatitis to henna (Lawsonia). Contact Dermatitis 1980;6:288-9. PubMed
- Cronin E. Immediate type hypersensitivity to henna. Contact Dermatitis 1979;5:198-9. PubMed
- Raupp P, Hassan JA, Varughese M, Kristiansson B. Henna causes life threatening haemolysis in glucose-6-phosphate dehydrogenase deficiency. Arch Dis Child 2001;85:411-2.. PubMed
- Akpolat ND, Aras A. Local hypertrichosis: A rare complication of a temporary henna tattoo. Turk J Pediatr. 2016;58(4):413-414. PubMed
- Goldscheider I, Herzinger T, Varga R, et al. Childhood lichen planus pemphigoides: report of two cases treated successfully with systemic glucocorticoids and dapsone. Pediatr Dermatol. 2014;31(6):751-3. PubMed
- Ilyas S, Wasif K, Saif MW. Topical henna ameliorated capecitabine-induced hand-foot syndrome. Cutan Ocul Toxicol. 2014;33(3):253-5. PubMed
- Katar S, Devecioglu C, Ozbek MN, Ecer S. Henna causes life-threatening hyperbilirubinaemia in glucose-6-phosphate dehydrogenase deficiency. Clin Exp Dermatol. 2007;32(2):235-6. PubMed
- Kheir A, Gaber I, Gafer S, Ahmed W. Life-threatening haemolysis induced by henna in a Sudanese child with glucose-6-phosphate dehydrogenase deficiency. East Mediterr Health J. 2017;23(1):28-30.
- Khine YY. Acute Kidney Injury following Ingestion of Henna Leaf Extract: A Case Report from Myanmar. Blood Purif. 2017;44 Suppl 1:41-45. PubMed
- Kind F, Scherer K, Bircher AJ. Contact dermatitis to para-phenylenediamine in hair dye following sensitization to black henna tattoos - an ongoing problem. J Dtsch Dermatol Ges. 2012;10(8):572-8. PubMed
- Rund D, Schaap T, Da'as N, Ben Yehuda D, Kalish J. Plasma exchange as treatment for Lawsone (henna) intoxication. J Clin Apher. 2007;22(4):243-5. PubMed
- Uygur-Bayramicli O, Dabak R, Sargin M. Acute chemical colitis resulting from oral intake of henna. J Clin Gastroenterol. 2005;39(10):920-1. PubMed
- Poursadra E, Anvari-Tafti M, Dehghani A, Eghbali-Babadi M, Rafiei Z. Comparing the effect of henna oil and olive oil on pressure ulcer grade one in intensive care units patients. Adv Biomed Res. 2019 Nov 27;8:68. PubMed
- Zibanejad S, Miraj S, Rafieian Kopaei M. Healing effect of Quercus persica and Lawsonia inermis ointment on episiotomy wounds in primiparous women. J Res Med Sci. 2020 Feb 20;25:11. PubMed
- Kubat S, Aksu H, Hasbal NB. Acute renal failure due to henna stone ingestion as a remedy of diabetes. Nefrologia. 2020 Jul 20:S0211-6995(20)30083-7. PubMed
- Asgari S, Esfandbod M, Haghshomar M. Henna-induced hemolysis and acute kidney injury in an 85-year-old man; A case report. Arch Acad Emerg Med. 2020 Oct 14;8(1):e82.
- Niazi M, Mehrabani M, Namazi MR, et al. Efficacy of a topical formulation of henna (Lawsonia inermis L.) in contact dermatitis in patients using prosthesis: A double-blind randomized placebo-controlled clinical trial. Complement Ther Med. 2020 Mar;49:1023 PubMed
- Arslan S, Zorba Bahceli P, Ilik Y, Artaç M. The preliminary effects of henna on chemotherapy-induced peripheral neuropathy in women receiving oxaliplatin-based treatment: A parallel-group, randomized, controlled pilot trial. Eur J Oncol Nurs. 2020 Oct;48: PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Henna and Deferiprone Together: Common Questions
Is it safe to take Henna with Deferiprone?
Do Henna and Deferiprone have any of the same side effects?
Should I take Henna and Deferiprone at the same time of day?
How was the Henna and Deferiprone combination checked?
Does Henna interact with any other medications?
Does Deferiprone interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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