Drug & supplement interaction

Isatis + Calcipotriene

Calcipotriene brand name: Dovonex.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Isatis and Calcipotriene in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Isatis and Calcipotriene

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Calcipotriene and Isatis in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Isatis at all — not against Calcipotriene, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Isatis safety at a glance

Isatis overall Use caution Generally used short-term in traditional medicine, but human safety data are limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid There is no reliable safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Calcipotriene and Isatis? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Calcipotriene’s Own FDA Label Lists

This is not an interaction — none of it involves Isatis. These are the most notable effects listed in the ADVERSE REACTIONS section of Calcipotriene’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both.

  • Itching mentioned in 5.4% of FDA reports for Calcipotriene
  • A skin rash mentioned in 5.0% of FDA reports for Calcipotriene

From the ADVERSE REACTIONS section of the FDA label for Calcipotriene. Read the label on DailyMed › Where a percentage is shown, it is the share of 6,726 voluntary FDA FAERS reports for Calcipotriene that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Isatis’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Isatis side to compare — that is a limit of the record, not a statement that Isatis has no side effects.

Overlapping uses

What Calcipotriene Is Prescribed For, and What Isatis Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Calcipotriene is a prescription medicine with approved uses on its FDA label. Isatis is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Calcipotriene is prescribed for: Calcipotriene is applied directly to the skin to treat plaque psoriasis — the common form of psoriasis that causes raised, scaly patches. Calcipotriene foam (brands include Sorilux) is approved for plaque psoriasis of the scalp and body in adults and children 4 years and older. Pellix Topical Solution is applied specifically to scalp psoriasis lesions. Calcitrene ointment (and related creams) is also used for plaque psoriasis, but should not be applied to the face.

Isatis has been studied for:

  • Psoriasis Natural Medicines rates the evidence for Isatis: Possibly Effective Read what the research shows

    Isatis for psoriasis

    Clinical research shows that topical isatis leaf extract may reduce the severity of nail psoriasis.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Calcipotriene on your own; if you are taking Isatis for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Calcipotriene

This page covers Isatis only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Calcipotriene page lists 5 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Calcium (moderate), Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate), Vitamin D (moderate) and Alchemilla (minor).

By severity: 4 moderate · 1 minor.

From our pharmacist’s overview on the Calcipotriene page

“Calcipotriene (Dovonex) is a psoriasis cream built around a lab-made form of vitamin D, and that is exactly why its short supplement list, just five ingredients, centers on calcium. Enough of the drug can soak through the skin to raise blood calcium, so taking vitamin D or calcium supplements alongside it can theoretically stack onto t…”

Reviewed by 2 · Jul 18, 2026

Open the Calcipotriene interaction page

One more smart check

Taking Isatis as Part of a Dietary Supplement Product? Check It for Interactions

We hold 413 real supplement products containing Isatis, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Isatis. Even though Isatis itself has no known interaction with Calcipotriene, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Isatis and Calcipotriene Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Isatis
Top 25%

#320 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Calcipotriene
Steady interest

#1,844 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Isatis is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Isatis reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Isatis and Calcipotriene records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Isatis

What is Isatis?

  • Colds and flu-like illness
  • Sore throat
  • Fever
  • Immune support
  • Antiviral and antimicrobial support

Isatis is a plant long used in traditional Chinese medicine, mainly for sore throats, fevers, and colds. Modern evidence in people is very limited, so its benefits are not well proven. Talk with your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Isatis tinctoria · Brassicaceae · Root (Ban Lan Gen) and leaf (Da Qing Ye) · Capsules, tablets, granules, powders, teas, and tinctures

An interaction check asks whether these two react with each other — it does not ask whether Isatis is a good idea for someone in your situation. Here is what our Isatis record says about it on its own.

Isatis: dosing

There is no well-established standard dose for Isatis. Traditional preparations and modern products vary widely in strength and form.If you choose to use it, follow the directions on the product label and do not exceed the recommended amount. A pharmacist or qualified healthcare provider can help you decide whether it is appropriate for you and review your other medicines and health conditions first.

From our Isatis monograph — the full record covers uses, side effects and every documented interaction.

Read the full Isatis monograph & all interactions
Medication

About Calcipotriene Topical

What Is Calcipotriene Topical Used For?

Brand name: Dovonex

Calcipotriene is applied directly to the skin to treat plaque psoriasis — the common form of psoriasis that causes raised, scaly patches. Calcipotriene foam (brands include Sorilux) is approved for plaque psoriasis of the scalp and body in adults and children 4 years and older.

Pellix Topical Solution is applied specifically to scalp psoriasis lesions. Calcitrene ointment (and related creams) is also used for plaque psoriasis, but should not be applied to the face.

Most-Reported Side Effects for Calcipotriene

From FAERS, the FDA’s public side-effect reporting system (6,726 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Psoriasis 1,364 reports
Diarrhea 433 reports
Headache 363 reports
Pruritus 360 reports
Nausea 359 reports
See full Calcipotriene Topical drug information
Keep checking

Other Drugs & Isatis

Browse every other medication we’ve checked against Isatis — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Isatis against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Isatis list.

See the full Isatis interactions page
See every supplement checked against Calcipotriene, ranked by severity
Evidence & sources

Isatis References

The 3 sources that drive our Isatis monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Isatis is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source
  3. About Herbs, Botanicals & Other Products — Memorial Sloan Kettering Cancer Center Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Isatis and Calcipotriene Together: Common Questions

Is it safe to take Isatis with Calcipotriene?
We do not list a known interaction between Isatis and Calcipotriene. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Isatis and Calcipotriene used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Isatis in each. That is a conversation for your prescriber, especially if Calcipotriene is being adjusted to a target.
Does Calcipotriene interact with any supplements?
Yes. Calcipotriene has documented interactions with 5 supplements in our database — Isatis is not one of them. The Calcipotriene interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Isatis monograph Uses, safety profile, and every drug interaction in one place Calcipotriene Topical drug information The full plain-English guide to this medication Calcipotriene supplement interactions Every supplement checked against Calcipotriene, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Calcipotriene and Isatis?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.