Herb & supplement monograph

Mountain Laurel Drug Interactions, Uses, Safety & More

Check Mountain Laurel against your medication

Add one medication
Mountain Laurel
+
Start typing any prescription or over-the-counter drug name.
Reviewed by licensed pharmacists Sourced from Natural Medicines
Interaction report

Drugs that interact with Mountain Laurel

0 medications have a known interaction with Mountain Laurel, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Mountain Laurel. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Mountain Laurel combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Mountain Laurel: Uses, Safety & Side Effects

The bottom line

Mountain Laurel is a flowering shrub native to North America that contains toxic compounds called grayanotoxins, making it dangerous to eat or use internally. There is no reliable evidence that it is safe or effective as a supplement, and poisoning can be serious. We strongly recommend avoiding it.

Scientific name
Kalmia latifolia
Family
Ericaceae
Part used
Leaves (historically); rarely used today
Common forms
Not commonly available as a supplement; historically used as crude leaf preparations or tinctures
People commonly use it for
  • Skin conditions (folk use)
  • Pain and inflammation (folk use)
  • Diarrhea (historical folk use)
  • Fever (historical folk use)

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallBest avoided

All parts of the plant are poisonous due to grayanotoxins and should not be taken internally.

PregnancyUnsafe

When used orally. There is insufficient reliable information available about safety of mountain laurel for topical use; avoid using.

Read the full pregnancy detail
BreastfeedingUnsafe

When used orally. There is insufficient reliable information available about safety of mountain laurel for topical use; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Mountain Laurel (Kalmia latifolia) is a flowering evergreen shrub in the heath family (Ericaceae). It grows wild across the eastern United States, especially in wooded and mountainous areas, and is well known for its showy pink and white spring flowers. It is often planted as an ornamental in gardens and landscapes.

While the plant has a long history in North American folk traditions, it is important to know that Mountain Laurel is poisonous. Native American and early settler accounts mention external use for certain skin and pain complaints, but the plant was generally recognized as toxic if eaten. Today it is not a mainstream dietary supplement, and reputable sources warn against ingesting any part of it.

Uses & effectiveness

There is no good scientific evidence that Mountain Laurel is safe or effective for any health condition. Its historical folk uses — including skin problems, pain, fever, and diarrhea — come from traditional practice, not from quality clinical research.

Because the plant contains toxic compounds, modern herbalists and health authorities do not recommend it for internal use. Any reported benefits are not backed by controlled human studies, and the known risks far outweigh any unproven benefit.

How it works

Mountain Laurel contains natural toxins called grayanotoxins (also found in some other plants in the heath family, such as rhododendrons and azaleas). These compounds affect sodium channels in nerve and muscle cells, which can interfere with the heart, nervous system, and muscles.

This is why the plant is dangerous rather than helpful when taken internally. There are no well-established medicinal mechanisms in humans, and most of what is known comes from cases of poisoning and from laboratory studies of grayanotoxins.

Safety & precautions

Mountain Laurel is toxic and should not be eaten or taken as a supplement. The leaves, flowers, stems, pollen, and even honey made from its nectar can contain grayanotoxins. Poisoning can cause symptoms ranging from mild stomach upset to serious heart and nervous system effects.

Children and pets are especially at risk because they may chew on the leaves or flowers. If you have this plant in your garden, keep it away from curious children and animals.

Pregnancy and breastfeeding: Avoid completely. There is no safe established use, and the plant's known toxicity makes it dangerous for both the parent and the baby.

If you suspect someone has eaten Mountain Laurel, contact Poison Control or seek emergency medical care right away.

Side effects

Eating Mountain Laurel can cause grayanotoxin poisoning. Symptoms may include nausea, vomiting, excessive salivation, watery eyes, low blood pressure, slow or irregular heartbeat, dizziness, weakness, and in severe cases trouble breathing, loss of consciousness, or life-threatening heart problems.

Even small amounts can be harmful, and the severity depends on the dose. Because of these dangers, Mountain Laurel is not considered safe to use as a remedy.

Mountain Laurel: Reported Adverse Effects

Documented safety reports on Mountain Laurel from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, mountain laurel can result in painful oral and gastric mucous membranes, increased salivation, cold sweat, nausea, vomiting, diarrhea, and paresthesias. Dizziness; headache; fever attacks; and intoxicated states with temporary loss of vision, muscle weakness, coordination disorders, and spasms can also develop. Bradycardia, cardiac arrhythmias, drop in blood pressure, eventual cardiac arrest, and respiratory failure can lead to death.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no established or safe dose of Mountain Laurel for any use. It is not recommended as a dietary supplement, and no standardized preparations are considered safe to take internally.

Because of its toxicity, the safest approach is to avoid using it altogether. If you are looking for a remedy for a specific health concern, talk to your pharmacist or doctor about safer, evidence-based options.

Pregnancy & Breastfeeding

Mountain Laurel & Pregnancy

Unsafe

When used orally. There is insufficient reliable information available about safety of mountain laurel for topical use; avoid using.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Mountain Laurel & Breastfeeding

Unsafe

When used orally. There is insufficient reliable information available about safety of mountain laurel for topical use; avoid using.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 references that drive our Mountain Laurel monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Mountain Laurel

1 brand in our database make a supplement containing Mountain Laurel.

Product directory

Supplement products with Mountain Laurel

2 products in our database contain Mountain Laurel. Open any to see its full ingredient list and every drug interaction we check.

Pharmacist Counseling Corner

Mountain Laurel: Common Questions

Does Mountain Laurel interact with prescription medications?
We do not currently list any known drug interactions for Mountain Laurel. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Mountain Laurel interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Mountain Laurel with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Mountain Laurel interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
Is Mountain Laurel safe to take as a supplement?
No. All parts of the plant contain toxic grayanotoxins and can cause serious poisoning if eaten. It is not recommended for internal use.
What is Mountain Laurel used for?
Historically it appeared in some North American folk traditions for skin and pain complaints, but there is no reliable evidence it works, and it is considered poisonous rather than medicinal today.
What happens if you eat Mountain Laurel?
Eating it can cause vomiting, low blood pressure, slow or irregular heartbeat, dizziness, and in severe cases life-threatening heart and nervous system problems. Seek emergency care or call Poison Control if ingestion is suspected.
Is honey made near Mountain Laurel dangerous?
Honey made from the nectar of Mountain Laurel and related plants can contain grayanotoxins and may cause 'mad honey' poisoning. This is rare with commercial honey but possible with certain raw, local honeys.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Keep exploring

Products that contain Mountain Laurel

A rotating sample of real supplements in our database that list Mountain Laurel — open any to see its full ingredients and every drug interaction we check.

Have a question about Mountain Laurel?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist