Drug & supplement interaction

Labdanum + Certolizumab

Certolizumab brand name: Cimzia.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Labdanum and Certolizumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Labdanum and Certolizumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Certolizumab and Labdanum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Labdanum at all — not against Certolizumab, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Labdanum safety at a glance

Labdanum overall Use caution Generally used topically or for fragrance; safety as an internal supplement is not well studied.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Certolizumab and Labdanum? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Labdanum and Certolizumab May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Labdanum

    “There is currently a limited amount of information on the adverse effects of labdanum. Orally, labdanum has been reported to cause nausea and stomach upset. Topically, labdanum has been reported to cause contact dermatitis.”

    Labdanum · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 98408. Kalus U, Grigorov A, Kadecki O, et al. Cistus incanus (CYSTUS052) for treating patients with infection of the upper respiratory tract. A prospective, randomised, placebo-controlled clinical study. Antiviral Res 2009;84(3):267-71. PubMed
    2. 98406. García-González JJ, Crespo V, Barber D, et al. Cistus ladanifer contact dermatitis. Contact Dermatitis 2001;45(4):238.
    3. 98407. English JSC, Cronin E. Allergic contact dermatitis from Cistus creticus. Contact Dermatitis 1988;18(2):123.

    “Topically, labdanum has been reported to cause contact dermatitis. In one case report, a 32-year-old man developed dermatitis on the hand after touching a Cistus ladanifer plant during a construction project. Allergen skin tests were positive for the leaf and leaf extract. In another case report, a woman developed contact dermatitis after exposure to a Cistus creticus plant in her garden.”

    Labdanum · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 98406. García-González JJ, Crespo V, Barber D, et al. Cistus ladanifer contact dermatitis. Contact Dermatitis 2001;45(4):238.
    2. 98407. English JSC, Cronin E. Allergic contact dermatitis from Cistus creticus. Contact Dermatitis 1988;18(2):123.

    Certolizumab

    Listed in the ADVERSE REACTIONS section of the FDA label for Certolizumab. Read the label on DailyMed ›

Reported for Labdanum but not commonly for Certolizumab: stomach upset and nausea.

Effects for Certolizumab come from the ADVERSE REACTIONS section of its FDA label; effects for Labdanum come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

One more smart check

Taking Labdanum as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Labdanum, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Labdanum. Even though Labdanum itself has no known interaction with Certolizumab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Labdanum and Certolizumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Labdanum
Steady interest

#749 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Certolizumab
Steady interest

#2,273 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Labdanum reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Labdanum and Certolizumab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Labdanum

What is Labdanum?

  • Fragrance and perfumery
  • Skin care
  • Incense and aromatherapy
  • Traditional wound and skin remedies
  • Relaxation and stress relief

Labdanum is a sticky, fragrant resin from the rockrose plant (Cistus ladanifer) that is used mainly in perfumes, incense, and aromatherapy. There is very little high-quality human research to support any health or medicinal use, so it should be viewed as a scent and cosmetic ingredient rather than a proven remedy.

Cistus ladanifer · Cistaceae · Sticky resin (oleoresin) and essential oil from the leaves and stems · Essential oil, absolute, resin (used in perfumes and incense), and occasionally in skin-care products

An interaction check asks whether these two react with each other — it does not ask whether Labdanum is a good idea for someone in your situation. Here is what our Labdanum record says about it on its own.

Labdanum: dosing

There is no established or standardized medicinal dose for labdanum. It is not commonly sold as an oral supplement, and reliable human dosing information does not exist.If you use a labdanum essential oil or skin product, follow the directions on the label and dilute essential oils as instructed.

From our Labdanum monograph — the full record covers uses, side effects and every documented interaction.

Read the full Labdanum monograph & all interactions
Medication

About Certolizumab Injection

What Is Certolizumab Injection Used For?

Brand name: Cimzia

Cimzia is used to treat several inflammatory conditions in adults: moderately to severely active Crohn's disease (in adults who haven't responded well to standard therapy), moderately to severely active rheumatoid arthritis, active psoriatic arthritis, active ankylosing spondylitis, active non-radiographic axial spondyloarthritis with signs of inflammation, and moderate-to-severe plaque psoriasis in adults who need systemic treatment or phototherapy.

Cimzia is also approved to treat active polyarticular juvenile idiopathic arthritis (pJIA) in patients 2 years of age and older — one of its few pediatric uses. Effectiveness for Crohn's disease in children and adolescents was not demonstrated in clinical study.

See full Certolizumab Injection drug information
Keep checking

Other Drugs & Labdanum

Browse every other medication we’ve checked against Labdanum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Labdanum References

The 3 references that drive our Labdanum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. García-González JJ, Crespo V, Barber D, et al. Cistus ladanifer contact dermatitis. Contact Dermatitis 2001;45(4):238.
  2. English JSC, Cronin E. Allergic contact dermatitis from Cistus creticus. Contact Dermatitis 1988;18(2):123.
  3. Kalus U, Grigorov A, Kadecki O, et al. Cistus incanus (CYSTUS052) for treating patients with infection of the upper respiratory tract. A prospective, randomised, placebo-controlled clinical study. Antiviral Res 2009;84(3):267-71. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Labdanum and Certolizumab Together: Common Questions

Is it safe to take Labdanum with Certolizumab?
We do not list a known interaction between Labdanum and Certolizumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Labdanum and Certolizumab have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Certolizumab and Labdanum?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.