Drug & supplement interaction

Labdanum + Mepolizumab

Mepolizumab brand name: Nucala.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Labdanum and Mepolizumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Labdanum and Mepolizumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mepolizumab and Labdanum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Labdanum at all — not against Mepolizumab, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Labdanum safety at a glance

Labdanum overall Use caution Generally used topically or for fragrance; safety as an internal supplement is not well studied.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mepolizumab and Labdanum? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Labdanum Itself Has Been Linked To

This is not an interaction — nothing below involves Mepolizumab. It is the side-effect record for Labdanum on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Labdanum, this list is the first place to look.

  • Stomach upset / Nausea Additional detail

    “There is currently a limited amount of information on the adverse effects of labdanum. Orally, labdanum has been reported to cause nausea and stomach upset. Topically, labdanum has been reported to cause contact dermatitis.”

    Labdanum · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 98408. Kalus U, Grigorov A, Kadecki O, et al. Cistus incanus (CYSTUS052) for treating patients with infection of the upper respiratory tract. A prospective, randomised, placebo-controlled clinical study. Antiviral Res 2009;84(3):267-71. PubMed
    2. 98406. García-González JJ, Crespo V, Barber D, et al. Cistus ladanifer contact dermatitis. Contact Dermatitis 2001;45(4):238.
    3. 98407. English JSC, Cronin E. Allergic contact dermatitis from Cistus creticus. Contact Dermatitis 1988;18(2):123.

    “Orally, labdanum has been reported to cause nausea and stomach upset in one clinical trial.”

    Labdanum · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 98408. Kalus U, Grigorov A, Kadecki O, et al. Cistus incanus (CYSTUS052) for treating patients with infection of the upper respiratory tract. A prospective, randomised, placebo-controlled clinical study. Antiviral Res 2009;84(3):267-71. PubMed
  • A skin rash Additional detail

    “Topically, labdanum has been reported to cause contact dermatitis. In one case report, a 32-year-old man developed dermatitis on the hand after touching a Cistus ladanifer plant during a construction project. Allergen skin tests were positive for the leaf and leaf extract. In another case report, a woman developed contact dermatitis after exposure to a Cistus creticus plant in her garden.”

    Labdanum · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 98406. García-González JJ, Crespo V, Barber D, et al. Cistus ladanifer contact dermatitis. Contact Dermatitis 2001;45(4):238.
    2. 98407. English JSC, Cronin E. Allergic contact dermatitis from Cistus creticus. Contact Dermatitis 1988;18(2):123.

Everything above comes from the Natural Medicines adverse-effect record for Labdanum — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Mepolizumab’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Mepolizumab column appears here.

One more smart check

Taking Labdanum as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Labdanum, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Labdanum. Even though Labdanum itself has no known interaction with Mepolizumab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Labdanum and Mepolizumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Labdanum
Steady interest

#1,204 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mepolizumab
Steady interest

#2,664 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Labdanum reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Labdanum and Mepolizumab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Labdanum

What is Labdanum?

  • Fragrance and perfumery
  • Skin care
  • Incense and aromatherapy
  • Traditional wound and skin remedies
  • Relaxation and stress relief

Labdanum is a sticky, fragrant resin from the rockrose plant (Cistus ladanifer) that is used mainly in perfumes, incense, and aromatherapy. There is very little high-quality human research to support any health or medicinal use, so it should be viewed as a scent and cosmetic ingredient rather than a proven remedy.

Cistus ladanifer · Cistaceae · Sticky resin (oleoresin) and essential oil from the leaves and stems · Essential oil, absolute, resin (used in perfumes and incense), and occasionally in skin-care products

An interaction check asks whether these two react with each other — it does not ask whether Labdanum is a good idea for someone in your situation. Here is what our Labdanum record says about it on its own.

Labdanum: dosing

There is no established or standardized medicinal dose for labdanum. It is not commonly sold as an oral supplement, and reliable human dosing information does not exist.If you use a labdanum essential oil or skin product, follow the directions on the label and dilute essential oils as instructed.

From our Labdanum monograph — the full record covers uses, side effects and every documented interaction.

Read the full Labdanum monograph & all interactions
Medication

About Mepolizumab Injection

What Is Mepolizumab Injection Used For?

Brand name: Nucala

Nucala is used as an add-on maintenance treatment — meaning it works alongside other medications, not instead of them. It is approved for severe asthma (in patients 6 years and older with high eosinophil levels), chronic rhinosinusitis with nasal polyps (CRSwNP) in adults 18 and older whose symptoms aren't controlled by nasal corticosteroids alone, and COPD in adults with an eosinophilic phenotype whose disease isn't adequately controlled.

Nucala is also approved to treat eosinophilic granulomatosis with polyangiitis (EGPA), a rare form of blood vessel inflammation, and hypereosinophilic syndrome (HES), a condition involving dangerously elevated eosinophil counts, in adults and adolescents 12 and older. It is not meant to relieve sudden asthma attacks or acute COPD flares.

Most-Reported Side Effects for Mepolizumab

From FAERS, the FDA’s public side-effect reporting system (49,399 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Asthma 12,767 reports
Dyspnea 10,576 reports
Wheezing 7,131 reports
Cough 5,100 reports
Therapeutic product effect incomplete 5,051 reports
See full Mepolizumab Injection drug information
Keep checking

Other Drugs & Labdanum

Browse every other medication we’ve checked against Labdanum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Labdanum against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Labdanum list.

See the full Labdanum interactions page
See every supplement checked against Mepolizumab, ranked by severity
Evidence & sources

Labdanum References

The 3 references that drive our Labdanum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. García-González JJ, Crespo V, Barber D, et al. Cistus ladanifer contact dermatitis. Contact Dermatitis 2001;45(4):238.
  2. English JSC, Cronin E. Allergic contact dermatitis from Cistus creticus. Contact Dermatitis 1988;18(2):123.
  3. Kalus U, Grigorov A, Kadecki O, et al. Cistus incanus (CYSTUS052) for treating patients with infection of the upper respiratory tract. A prospective, randomised, placebo-controlled clinical study. Antiviral Res 2009;84(3):267-71. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Labdanum and Mepolizumab Together: Common Questions

Is it safe to take Labdanum with Mepolizumab?
We do not list a known interaction between Labdanum and Mepolizumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Labdanum monograph Uses, safety profile, and every drug interaction in one place Mepolizumab Injection drug information The full plain-English guide to this medication Mepolizumab supplement interactions Every supplement checked against Mepolizumab, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Mepolizumab and Labdanum?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.