Drug & supplement interaction

Maca + Sodium Sulfacetamide, Witch Hazel (orescription drug)

Sodium Sulfacetamide, Witch Hazel (orescription drug) brand name: Plexion SCT cream.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Maca and Sodium Sulfacetamide, Witch Hazel (orescription drug) in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Maca and Sodium Sulfacetamide, Witch Hazel (orescription drug)

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Sodium Sulfacetamide, Witch Hazel (orescription drug) and Maca in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Maca at all — not against Sodium Sulfacetamide, Witch Hazel (orescription drug), and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Maca safety at a glance

Maca overall Use caution Generally well tolerated as a food, but supplement safety has not been studied long term.
Pregnancy Avoid Not enough safety data in supplement amounts, so avoid during pregnancy.
Breastfeeding Avoid There is not enough reliable information on safety while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Sodium Sulfacetamide, Witch Hazel (orescription drug) and Maca? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Maca Itself Has Been Linked To

This is not an interaction — nothing below involves Sodium Sulfacetamide, Witch Hazel (orescription drug). It is the side-effect record for Maca on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Maca, this list is the first place to look.

  • Stomach pain Additional detail

    “Consumption of fresh, uncooked maca may cause stomach pain.”

    Maca · Natural Medicines adverse-effect record, reported in pain.

    1 source cited
    1. 40231. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Maca — expand a row for the licensed statement it rests on. We haven’t matched Sodium Sulfacetamide, Witch Hazel (orescription drug) to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Sodium Sulfacetamide, Witch Hazel (orescription drug).

Everything else you take

See Every Supplement That Interacts With Sodium Sulfacetamide, Witch Hazel (orescription drug)

This page covers Maca only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sodium Sulfacetamide, Witch Hazel (orescription drug) page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Sodium Sulfacetamide, Witch Hazel (orescription drug) page

“Plexion SCT, the prescription cream that pairs sodium sulfacetamide with witch hazel for acne and rosacea, works at the skin surface, so its supplement interactions are about skin too. Just three ingredients are on file, none rated major, and this is a workable list for most people provided they know which combinations to watch.”

Reviewed by 2 · Jul 18, 2026

Open the Sodium Sulfacetamide, Witch Hazel (orescription drug) interaction page

One more smart check

Taking Maca as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2,489 real supplement products containing Maca, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Maca. Even though Maca itself has no known interaction with Sodium Sulfacetamide, Witch Hazel (orescription drug), another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Maca and Sodium Sulfacetamide, Witch Hazel (orescription drug) Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Maca
Top 5%

#72 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Sodium Sulfacetamide, Witch Hazel (orescription drug)
Steady interest

#2,458 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Maca reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Maca and Sodium Sulfacetamide, Witch Hazel (orescription drug) records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Maca

What is Maca?

Maca
  • Low libido and sexual function
  • Energy and stamina
  • Menopause symptoms
  • Mood and stress
  • Fertility support

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire and some menopause symptoms, but the evidence is limited and not conclusive. It appears generally well tolerated in food amounts, but talk to your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have a hormone-related condition.

Lepidium meyenii · Brassicaceae · Root (hypocotyl) · Capsules, powder, tablets, liquid extracts, gelatinized powder

An interaction check asks whether these two react with each other — it does not ask whether Maca is a good idea for someone in your situation. Here is what our Maca record says about it on its own.

Maca: dosing

There is no official or standardized dose of maca, and the amounts used in studies have varied widely. Because of this, it is best to follow the directions on the product label.Maca is sold in different forms, including raw powder, gelatinized powder, capsules, and extracts, and the strength can differ between products. Do not assume that taking more will work better or be safer.

From our Maca monograph — the full record covers uses, side effects and every documented interaction.

Read the full Maca monograph & all interactions
Keep checking

Other Drugs & Maca

Browse every other medication we’ve checked against Maca — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Maca against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Maca list.

See the full Maca interactions page
See every supplement checked against Sodium Sulfacetamide, Witch Hazel (orescription drug), ranked by severity
Evidence & sources

Maca References

The 1 references that drive our Maca monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Maca and Sodium Sulfacetamide, Witch Hazel (orescription drug) Together: Common Questions

Is it safe to take Maca with Sodium Sulfacetamide, Witch Hazel (orescription drug)?
We do not list a known interaction between Maca and Sodium Sulfacetamide, Witch Hazel (orescription drug). That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Sodium Sulfacetamide, Witch Hazel (orescription drug) interact with any supplements?
Yes. Sodium Sulfacetamide, Witch Hazel (orescription drug) has documented interactions with 3 supplements in our database — Maca is not one of them. The Sodium Sulfacetamide, Witch Hazel (orescription drug) interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Maca monograph Uses, safety profile, and every drug interaction in one place Sodium Sulfacetamide, Witch Hazel (orescription drug) supplement interactions Every supplement checked against Sodium Sulfacetamide, Witch Hazel (orescription drug), ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Sodium Sulfacetamide, Witch Hazel (orescription drug) and Maca?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.