Drug & supplement interaction

Moneywort + Dolutegravir

Dolutegravir brand name: Tivicay.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Moneywort and Dolutegravir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Moneywort and Dolutegravir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dolutegravir and Moneywort in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Moneywort at all — not against Dolutegravir, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Moneywort safety at a glance

Moneywort overall Not established There is little reliable human safety data, so use cautiously and consult a professional.
Pregnancy Avoid Safety has not been studied; avoid use during pregnancy.
Breastfeeding Avoid No reliable data on safety while breastfeeding; best to avoid.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dolutegravir and Moneywort? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Dolutegravir’s Own FDA Label Lists

This is not an interaction — none of it involves Moneywort. These are the most notable effects listed in the ADVERSE REACTIONS section of Dolutegravir’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Liver problems Worth acting on
  • An allergic reaction Worth acting on
  • Trouble sleeping
  • Tiredness mentioned in 5.4% of FDA reports for Dolutegravir
  • Headache mentioned in 4.6% of FDA reports for Dolutegravir
  • A skin rash

From the ADVERSE REACTIONS section of the FDA label for Dolutegravir. Read the label on DailyMed › Where a percentage is shown, it is the share of 19,465 voluntary FDA FAERS reports for Dolutegravir that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Moneywort’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Moneywort side to compare — that is a limit of the record, not a statement that Moneywort has no side effects.

Everything else you take

See Every Supplement That Interacts With Dolutegravir

This page covers Moneywort only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dolutegravir page lists 65 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Calcium (major), St. John's Wort (major), Bitter Melon (moderate) and Black Pepper (moderate).

By severity: 3 major · 46 moderate · 16 minor.

From our pharmacist’s overview on the Dolutegravir page

“Dolutegravir (Tivicay) works only when its blood level stays high enough to keep HIV suppressed, so a supplement that drags that level down can let the virus rebound, and this list warrants genuine care. Three of the 65 entries are rated major.”

Reviewed by 2 · Jul 18, 2026

Open the Dolutegravir interaction page

How much people look this up

Where Moneywort and Dolutegravir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Moneywort
Steady interest

#1,142 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dolutegravir
Steady interest

#1,895 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Moneywort is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Moneywort reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Moneywort and Dolutegravir records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Moneywort

What is Moneywort?

Moneywort
  • Wound healing
  • Mild diarrhea
  • Cough and respiratory complaints
  • Minor skin irritation
  • Mild bleeding (traditional)

Moneywort (Creeping Jenny) is a low-growing garden plant used in some folk traditions for wounds, coughs, and digestive upset, but there is very little scientific research to confirm any of these uses. Because solid safety and effectiveness data are lacking, it is best to talk with a pharmacist or doctor before using it, and to avoid it during pregnancy and breastfeeding.

Lysimachia nummularia · Primulaceae · Aerial parts (leaves, stems, and flowers) · Tea, dried herb, tincture, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Moneywort is a good idea for someone in your situation. Here is what our Moneywort record says about it on its own.

Moneywort: dosing

There is no established or standardized dose for Moneywort. Because it has not been studied in well-designed human trials, experts cannot recommend a specific amount that is both safe and effective.If you choose to use a commercial product, follow the directions on the label and do not exceed them. A pharmacist can help you review the product and decide whether it is appropriate for you. When in doubt, less is safer, and always start with the smallest amount.

From our Moneywort monograph — the full record covers uses, side effects and every documented interaction.

Read the full Moneywort monograph & all interactions
Medication

About Dolutegravir

What Is Dolutegravir Used For?

Brand name: Tivicay

Tivicay and Tivicay PD are used to treat HIV-1 infection. They are always taken in combination with other antiretroviral medicines — they are not used alone. Both products are approved for adults (whether new to treatment or previously treated) and for children who have not previously been treated with an integrase inhibitor (INSTI).

Tivicay (the standard tablet) has an additional use: it can be combined with rilpivirine as a complete two-drug regimen for adults whose HIV is already well controlled (virologically suppressed) on a stable treatment plan for at least 6 months, with no history of treatment failure or known resistance to either drug.

Most-Reported Side Effects for Dolutegravir

From FAERS, the FDA’s public side-effect reporting system (19,465 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Anxiety 1,892 reports
Emotional distress 1,748 reports
Anhedonia 1,579 reports
Chronic kidney disease 1,161 reports
Fatigue 1,057 reports
See full Dolutegravir drug information
Keep checking

Other Drugs & Moneywort

Browse every other medication we’ve checked against Moneywort — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Moneywort against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Moneywort list.

See the full Moneywort interactions page
See every supplement checked against Dolutegravir, ranked by severity
Evidence & sources

Moneywort References

The 1 sources that drive our Moneywort monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Moneywort is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Using Dietary Supplements Wisely — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Moneywort and Dolutegravir Together: Common Questions

Is it safe to take Moneywort with Dolutegravir?
We do not list a known interaction between Moneywort and Dolutegravir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Dolutegravir interact with any supplements?
Yes. Dolutegravir has documented interactions with 65 supplements in our database — Moneywort is not one of them. The Dolutegravir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Moneywort monograph Uses, safety profile, and every drug interaction in one place Dolutegravir drug information The full plain-English guide to this medication Dolutegravir supplement interactions Every supplement checked against Dolutegravir, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Dolutegravir and Moneywort?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.