Moneywort + Hydroxychloroquine
Hydroxychloroquine brand name: Plaquenil.
We found no known interaction between Moneywort and Hydroxychloroquine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Hydroxychloroquine states a food rule worth keeping to.
Moneywort and Hydroxychloroquine
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Hydroxychloroquine and Moneywort in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Moneywort at all — not against Hydroxychloroquine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Moneywort safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Hydroxychloroquine Products Have a Food Rule — Moneywort Should Not Break It
At least one FDA label for a product containing Hydroxychloroquine says to take it with food. If you take Moneywort on an empty stomach out of habit, keep them separate — and take Hydroxychloroquine with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Hydroxychloroquine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Rheumatoid Arthritis in Adults ( 2.3 ): Initial dosage: 400 mg to 600 mg daily Chronic dosage: 200 mg once daily or 400 mg once daily (or in two divided doses) Systemic Lupus Erythematosus in Adults ( 2.4 ): 200 mg once daily or 400 mg once daily (or in two divided doses) Chronic Discoid Lupus Erythematosus in Adults ( 2.5 ): 200 mg once daily or 400 mg once daily (or in two divided doses) 2.1 Imp
From the Dosage and Administration section of the FDA label we read for Hydroxychloroquine — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
Questions About Moneywort or Hydroxychloroquine
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Moneywort or Hydroxychloroquine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Hydroxychloroquine
This page covers Moneywort only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Hydroxychloroquine page lists 32 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).
By severity: 7 major · 16 moderate · 9 minor.
From our pharmacist’s overview on the Hydroxychloroquine page
“Hydroxychloroquine (Plaquenil) can stretch the QT interval on its own, the pause between heartbeats that, prolonged too far, can trigger a dangerous rhythm. Thirteen of the supplements and herbs on this page add to that same effect, grapefruit in large amounts among them, and that overlap is why this list calls for genuine care rather…”
Reviewed by 2 · Jul 18, 2026
Where Moneywort and Hydroxychloroquine Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,170 of 1,452 supplements looked up here in the last 7 days
#339 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Moneywort is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Moneywort reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Moneywort and Hydroxychloroquine records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Moneywort
What is Moneywort?
- Wound healing
- Mild diarrhea
- Cough and respiratory complaints
- Minor skin irritation
- Mild bleeding (traditional)
Moneywort (Creeping Jenny) is a low-growing garden plant used in some folk traditions for wounds, coughs, and digestive upset, but there is very little scientific research to confirm any of these uses. Because solid safety and effectiveness data are lacking, it is best to talk with a pharmacist or doctor before using it, and to avoid it during pregnancy and breastfeeding.
Lysimachia nummularia · Primulaceae · Aerial parts (leaves, stems, and flowers) · Tea, dried herb, tincture, topical preparations
An interaction check asks whether these two react with each other — it does not ask whether Moneywort is a good idea for someone in your situation. Here is what our Moneywort record says about it on its own.
Moneywort: dosing
There is no established or standardized dose for Moneywort. Because it has not been studied in well-designed human trials, experts cannot recommend a specific amount that is both safe and effective.If you choose to use a commercial product, follow the directions on the label and do not exceed them. A pharmacist can help you review the product and decide whether it is appropriate for you. When in doubt, less is safer, and always start with the smallest amount.
From our Moneywort monograph — the full record covers uses, side effects and every documented interaction.
About Hydroxychloroquine
What Is Hydroxychloroquine Used For?
Brand name: Plaquenil
Hydroxychloroquine tablets are used to treat uncomplicated malaria and to help prevent malaria in areas where the parasite has not developed resistance to it — in both adults and children. It is also used in adults to treat rheumatoid arthritis, systemic lupus erythematosus (SLE), and chronic discoid lupus erythematosus.
There are important limits: it is not recommended for complicated or drug-resistant malaria, malaria acquired in regions where resistance is known, or to prevent malaria relapses caused by P. vivax or P. ovale. Its use for the autoimmune conditions (rheumatoid arthritis and lupus) is approved for adults only.
Other Drugs & Moneywort
Browse every other medication we’ve checked against Moneywort — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Moneywort against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Ivermectin ›
- Losartan Potassium ›
- Aspirin ›
- Abemaciclib ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Warfarin Sodium ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Amitriptyline ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Moneywort list.
Moneywort References
The 1 sources that drive our Moneywort monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Moneywort is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Using Dietary Supplements Wisely — NIH NCCIH Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Moneywort and Hydroxychloroquine Together: Common Questions
Is it safe to take Moneywort with Hydroxychloroquine?
Should I take Moneywort and Hydroxychloroquine at the same time of day?
Does Hydroxychloroquine interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Hydroxychloroquine and Moneywort?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.