Drug & supplement interaction

Muira Puama + Risankizumab-Rzaa

Risankizumab-Rzaa brand name: Skyrizi.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Muira Puama and Risankizumab-Rzaa in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Muira Puama and Risankizumab-Rzaa

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Risankizumab-Rzaa and Muira Puama in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Muira Puama at all — not against Risankizumab-Rzaa, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Muira Puama safety at a glance

Muira Puama overall Use caution Generally used in small amounts traditionally, but human safety data are limited.
Pregnancy Avoid Not enough safety information; avoid during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Risankizumab-Rzaa and Muira Puama? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Risankizumab-Rzaa’s Own FDA Label Lists

This is not an interaction — none of it involves Muira Puama. These are the most notable effects listed in the ADVERSE REACTIONS section of Risankizumab-Rzaa’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 7 of them are worth acting on rather than waiting out — marked below.

  • Anemia Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • Liver problems Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • A stuffy or runny nose
  • Sore throat
  • Back pain

Showing the 10 most notable of 18 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Risankizumab-Rzaa. Read the label on DailyMed › Muira Puama’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Muira Puama side to compare — that is a limit of the record, not a statement that Muira Puama has no side effects.

Overlapping uses

What Risankizumab-Rzaa Is Prescribed For, and What Muira Puama Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Risankizumab-Rzaa is a prescription medicine with approved uses on its FDA label. Muira Puama is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Risankizumab-Rzaa is prescribed for: Risankizumab-rzaa (brand name Skyrizi) treats several long-term inflammatory conditions. These are moderate-to-severe plaque psoriasis and active psoriatic arthritis, in adults and children 6 years and older. It also treats moderately to severely active Crohn's disease and ulcerative colitis in adults. For plaque psoriasis, it is for people who are candidates for systemic therapy (treatment that works throughout the body) or phototherapy (light treatment).

Muira Puama has been studied for:

  • Joint pain studied, not established Muira Puama has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Muira Puama for joint pain

    Although there has been interest in using oral or topical muira puama for joint pain, there is insufficient reliable information about the clinical effects of muira puama for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Risankizumab-Rzaa on your own; if you are taking Muira Puama for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Risankizumab-Rzaa

This page covers Muira Puama only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Risankizumab-Rzaa page lists 53 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Active Hexose Correlated Compound (ahcc) (moderate), Alfalfa (moderate), American Ginseng (moderate), Andrographis (moderate) and Ashwagandha (moderate).

By severity: 52 moderate · 1 minor.

From our pharmacist’s overview on the Risankizumab-Rzaa page

“Echinacea captures the concern on this page better than any other entry. Risankizumab-rzaa (Skyrizi) treats plaque psoriasis, psoriatic arthritis, and Crohn's disease by quieting one arm of the immune system, and echinacea, like nearly all 53 ingredients listed here, is taken specifically to stir the immune system up.”

Reviewed by 2 · Jul 18, 2026

Open the Risankizumab-Rzaa interaction page

One more smart check

Taking Muira Puama as Part of a Dietary Supplement Product? Check It for Interactions

We hold 698 real supplement products containing Muira Puama, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Muira Puama. Even though Muira Puama itself has no known interaction with Risankizumab-Rzaa, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Muira Puama and Risankizumab-Rzaa Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Muira Puama
Top 25%

#292 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Risankizumab-Rzaa
Top half

#755 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Muira Puama is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Muira Puama reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Muira Puama and Risankizumab-Rzaa records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Muira Puama

What is Muira Puama?

  • Low libido
  • Erectile difficulty
  • Sexual performance
  • Fatigue and low energy
  • General tonic for stress

Muira puama is a Brazilian plant traditionally used as an aphrodisiac and general tonic, often nicknamed 'potency wood.' Human research is very limited, so its benefits are not well proven, and there is little information on its long-term safety. Talk with your pharmacist or doctor before trying it, especially if you have a health condition or take other medicines.

Ptychopetalum olacoides · Olacaceae · Roots and bark (sometimes wood) · Capsules, tinctures, liquid extracts, teas, and powders

An interaction check asks whether these two react with each other — it does not ask whether Muira Puama is a good idea for someone in your situation. Here is what our Muira Puama record says about it on its own.

Muira Puama: dosing

There is no well-established or standardized dose for muira puama. Products differ in form (capsule, tincture, tea) and in how concentrated they are, so amounts on labels vary widely.The safest approach is to follow the directions on the specific product you buy and to start low.

From our Muira Puama monograph — the full record covers uses, side effects and every documented interaction.

Read the full Muira Puama monograph & all interactions
Medication

About Risankizumab-rzaa Injection

What Is Risankizumab-rzaa Injection Used For?

Brand name: Skyrizi

Risankizumab-rzaa (brand name Skyrizi) treats several long-term inflammatory conditions. These are moderate-to-severe plaque psoriasis and active psoriatic arthritis, in adults and children 6 years and older. It also treats moderately to severely active Crohn's disease and ulcerative colitis in adults.

For plaque psoriasis, it is for people who are candidates for systemic therapy (treatment that works throughout the body) or phototherapy (light treatment).

See full Risankizumab-rzaa Injection drug information Risankizumab-Rzaa NDC codes and packages
Keep checking

Other Drugs & Muira Puama

Browse every other medication we’ve checked against Muira Puama — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Muira Puama against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Muira Puama list.

See the full Muira Puama interactions page
See every supplement checked against Risankizumab-Rzaa, ranked by severity
Evidence & sources

Muira Puama References

The 1 sources that drive our Muira Puama monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Muira Puama is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Muira Puama and Risankizumab-Rzaa Together: Common Questions

Is it safe to take Muira Puama with Risankizumab-Rzaa?
We do not list a known interaction between Muira Puama and Risankizumab-Rzaa. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Muira Puama and Risankizumab-Rzaa used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Muira Puama in each. That is a conversation for your prescriber, especially if Risankizumab-Rzaa is being adjusted to a target.
Does Risankizumab-Rzaa interact with any supplements?
Yes. Risankizumab-Rzaa has documented interactions with 53 supplements in our database — Muira Puama is not one of them. The Risankizumab-Rzaa interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Muira Puama monograph Uses, safety profile, and every drug interaction in one place Risankizumab-rzaa Injection drug information The full plain-English guide to this medication Risankizumab-Rzaa supplement interactions Every supplement checked against Risankizumab-Rzaa, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Risankizumab-Rzaa and Muira Puama?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.