Pao Pereira + Interferon Beta-1a
Interferon Beta-1a brand names: Rebif, Avonex.
We found no known interaction between Pao Pereira and Interferon Beta-1a in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Pao Pereira and Interferon Beta-1a
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Interferon Beta-1a and Pao Pereira in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Pao Pereira at all — not against Interferon Beta-1a, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Pao Pereira safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Interferon Beta-1a
This page covers Pao Pereira only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Interferon Beta-1a page lists 57 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Alfalfa (moderate) and Angelica Archangelica (moderate).
By severity: 3 major · 53 moderate · 1 minor.
From our pharmacist’s overview on the Interferon Beta-1a page
“Siberian cocklebur, an herb tied to documented cases of liver failure, is the first name to know for anyone injecting interferon beta-1a (Rebif, Avonex) for multiple sclerosis. Interferon beta-1a can strain the liver on its own, which is why prescribers order routine liver blood tests, and 38 of the 57 supplements on file carry that sa…”
Reviewed by 2 · Jul 18, 2026
Taking Pao Pereira as Part of a Dietary Supplement Product? Check It for Interactions
We hold 1 real supplement products containing Pao Pereira, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Pao Pereira. Even though Pao Pereira itself has no known interaction with Interferon Beta-1a, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Pao Pereira and Interferon Beta-1a Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,266 of 1,452 supplements looked up here in the last 7 days
#1,745 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Pao Pereira is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pao Pereira reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Pao Pereira and Interferon Beta-1a records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Pao Pereira
What is Pao Pereira?
- Immune support
- Cancer support (complementary use)
- Antimalarial/fever (traditional)
- Digestive complaints (traditional)
- General tonic
Pao Pereira is a bark extract from a South American tree that is marketed mainly as a complementary cancer and immune-support supplement. Human evidence is very limited, and most research comes from laboratory and animal studies, so it should not be used in place of proven medical care. Talk with your pharmacist or doctor before trying it, especially if you have a serious health condition.
Geissospermum laeve · Apocynaceae · Bark (and bark extract) · Capsules, tinctures, liquid extracts, powdered bark
An interaction check asks whether these two react with each other — it does not ask whether Pao Pereira is a good idea for someone in your situation. Here is what our Pao Pereira record says about it on its own.
Pao Pereira: dosing
There is no established or standardized dose for Pao Pereira. Different products contain different amounts and strengths of bark extract.If you choose to use it, follow the directions on the product label and do not exceed the recommended amount.
From our Pao Pereira monograph — the full record covers uses, side effects and every documented interaction.
About Interferon Beta-1a Intramuscular Injection
What Is Interferon Beta-1a Intramuscular Injection Used For?
Brand names: Rebif, Avonex
-
Interferon beta-1a intramuscular injection is used to treat adults with various forms of multiple sclerosis (MS; a disease in which the nerves do not function properly and people may experience weakness, numbness, loss of muscle coordination, and problems with vision, speech, and bladder control) including:
-
clinically isolated syndrome (CIS; nerve symptom episodes that last at least 24 hours),
-
relapsing-remitting forms (course of disease where symptoms flare up from time to time), or
-
secondary progressive forms (course of disease where relapses occur more often).
-
-
Interferon beta-1a is in a class of medications called immunomodulators. It works by decreasing inflammation and preventing nerve damage that may cause symptoms of multiple sclerosis.
Most-Reported Side Effects for Interferon Beta-1a
From FAERS, the FDA’s public side-effect reporting system (192,069 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Pao Pereira
Browse every other medication we’ve checked against Pao Pereira — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Pao Pereira against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Methylphenidate ›
- Sertraline ›
- Testosterone ›
- Ivermectin ›
- Losartan Potassium ›
- Aspirin ›
- Abemaciclib ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Warfarin Sodium ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Amitriptyline ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Pao Pereira list.
Pao Pereira References
The 4 sources that drive our Pao Pereira monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Pao Pereira is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- About Herbs, Botanicals & Other Products — Memorial Sloan Kettering Cancer Center Source
- Using Dietary Supplements Wisely — NIH NCCIH Source
- Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
- Herbs at a Glance — NIH NCCIH Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Pao Pereira and Interferon Beta-1a Together: Common Questions
Is it safe to take Pao Pereira with Interferon Beta-1a?
Does Interferon Beta-1a interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Interferon Beta-1a and Pao Pereira?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.