Drug & supplement interaction

Pellitory + Nelarabine

Nelarabine brand name: Atriance.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Pellitory and Nelarabine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Interaction report

Pellitory and Nelarabine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Nelarabine and Pellitory in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Pellitory at all — not against Nelarabine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pellitory safety at a glance

Pellitory overall Use caution Limited safety data exist, and it may cause mouth irritation or allergic reactions.
Pregnancy Avoid Not enough safety information is available, so it is best avoided.
Breastfeeding Avoid There is no reliable safety data during breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Nelarabine and Pellitory? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Nelarabine’s Own FDA Label Lists

This is not an interaction — none of it involves Pellitory. These are the most notable effects listed in the ADVERSE REACTIONS section of Nelarabine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Muscle weakness Worth acting on mentioned in 5.8% of FDA reports for Nelarabine
  • Low magnesium Worth acting on
  • Severe muscle breakdown Worth acting on
  • Memory problems Worth acting on
  • Dehydration Worth acting on
  • Unsteadiness Worth acting on
  • Low blood sugar Worth acting on
  • Low potassium Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • High blood sugar Worth acting on

Showing the 10 most notable of 51 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Nelarabine. Read the label on DailyMed › Where a percentage is shown, it is the share of 956 voluntary FDA FAERS reports for Nelarabine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Pellitory’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Pellitory side to compare — that is a limit of the record, not a statement that Pellitory has no side effects.

Everything else you take

See Every Supplement That Interacts With Nelarabine

This page covers Pellitory only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Nelarabine page lists 130 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major), Kava (major) and L-tryptophan (major).

By severity: 6 major · 118 moderate · 6 minor.

From our pharmacist’s overview on the Nelarabine page

“Nelarabine (Atriance) is chemotherapy for a rare T-cell leukemia and lymphoma, and its most feared side effect is damage to the nervous system, from heavy drowsiness up to seizures. Most of the 130 supplement and herbal ingredients on this list press on exactly that weak point.”

Reviewed by 2 · Jul 18, 2026

Open the Nelarabine interaction page

One more smart check

Taking Pellitory as Part of a Dietary Supplement Product? Check It for Interactions

We hold 36 real supplement products containing Pellitory, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Pellitory. Even though Pellitory itself has no known interaction with Nelarabine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Pellitory and Nelarabine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pellitory
Top half

#582 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Nelarabine
Steady interest

#2,406 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pellitory reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Pellitory and Nelarabine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Pellitory

What is Pellitory?

  • Toothache and oral discomfort
  • Increasing saliva flow
  • Sluggish digestion
  • Traditional tonic in some folk medicine systems

Pellitory (often Anacyclus pyrethrum, the root traditionally called 'pellitory of Spain') is an herb chiefly known in folk and traditional medicine for numbing toothache and stimulating saliva. Human evidence for its benefits is very limited, so it should be viewed as a traditional remedy rather than a proven treatment. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Anacyclus pyrethrum · Asteraceae · Root · Powder, root extract, tinctures, tooth powders and mouthwashes

An interaction check asks whether these two react with each other — it does not ask whether Pellitory is a good idea for someone in your situation. Here is what our Pellitory record says about it on its own.

Pellitory: dosing

There is no well-established, standardized dose for pellitory, and product strengths vary widely.

From our Pellitory monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pellitory monograph & all interactions
Medication

About Nelarabine Injection

What Is Nelarabine Injection Used For?

Brand name: Atriance

Nelarabine injection (brand name Arranon) is used to treat two aggressive blood cancers: T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL). It is approved for adult and pediatric patients age 1 year and older whose disease has not responded to — or has come back after — at least two prior chemotherapy regimens.

Nelarabine injection may also be given in combination with multi-agent chemotherapy as part of treatment for newly diagnosed T-ALL and T-LBL in certain settings, as studied in clinical trials.

Most-Reported Side Effects for Nelarabine

From FAERS, the FDA’s public side-effect reporting system (956 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Febrile neutropenia 75 reports
Neuropathy peripheral 60 reports
Neurotoxicity 60 reports
Sepsis 56 reports
Muscular weakness 55 reports
See full Nelarabine Injection drug information
Keep checking

Other Drugs & Pellitory

Browse every other medication we’ve checked against Pellitory — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Pellitory References

The 1 references that drive our Pellitory monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Pellitory and Nelarabine Together: Common Questions

Is it safe to take Pellitory with Nelarabine?
We do not list a known interaction between Pellitory and Nelarabine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Nelarabine interact with any supplements?
Yes. Nelarabine has documented interactions with 130 supplements in our database — Pellitory is not one of them. The Nelarabine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Nelarabine and Pellitory?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.