Drug & supplement interaction

Reed Herb + Palifermin

Palifermin brand name: Kepivance.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated June 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Reed Herb and Palifermin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share

Facebook Post Reddit Email

On this page

Interaction report

Reed Herb and Palifermin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Palifermin and Reed Herb in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Reed Herb at all — not against Palifermin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Reed Herb safety at a glance

Reed Herb overall Use caution Traditionally used and generally well tolerated, but human safety data are limited.

Pregnancy Avoid Not enough safety information; best to avoid during pregnancy.

Breastfeeding Avoid No reliable safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Palifermin and Reed Herb? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

What to actually watch for

What Palifermin’s Own FDA Label Lists

This is not an interaction — none of it involves Reed Herb. These are the most notable effects listed in the ADVERSE REACTIONS section of Palifermin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. One of them is worth acting on rather than waiting out — marked below.

A higher chance of infection Worth acting on mentioned in 6.2% of FDA reports for Palifermin
Fever mentioned in 16.0% of FDA reports for Palifermin
Numbness or tingling
Joint pain
A skin rash mentioned in 10.1% of FDA reports for Palifermin
Itching
Swelling

From the ADVERSE REACTIONS section of the FDA label for Palifermin. Read the label on DailyMed › Where a percentage is shown, it is the share of 388 voluntary FDA FAERS reports for Palifermin that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Reed Herb’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Reed Herb side to compare — that is a limit of the record, not a statement that Reed Herb has no side effects.

Overlapping uses

What Palifermin Is Prescribed For, and What Reed Herb Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Palifermin is a prescription medicine with approved uses on its FDA label. Reed Herb is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Palifermin is prescribed for: Kepivance (palifermin) is used to decrease how often and how long severe oral mucositis — painful sores in the mouth and throat — occurs in patients with hematologic malignancies (blood cancers such as lymphoma, leukemia, or multiple myeloma) who are receiving high-dose, cell-damaging (myelotoxic) therapy before an autologous hematopoietic stem cell transplant (a transplant using the patient's own stem cells). Kepivance is specifically indicated when the preparative chemotherapy or radiation regimen is expected to cause severe mucositis in most patients. It is not recommended for use with a high-dose melphalan conditioning regimen, and it was not found to be effective in the setting of allogeneic stem cell transplant (using a donor's cells). Its safety and effectiveness have not been established for patients with non-blood cancers (non-hematologic malignancies).

Reed Herb has been studied for:

Leukemia studied, not established Reed Herb has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

Reed Herb for leukemia

Although there has been interest in using oral reed herb for leukemia, there is insufficient reliable information about the clinical effects of reed herb for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Palifermin on your own; if you are taking Reed Herb for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Palifermin

This page covers Reed Herb only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Palifermin page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Palifermin page

“Palifermin (Kepivance) is given by IV to prevent the severe mouth sores that intensive chemotherapy can cause, most often in patients heading into a stem cell transplant, and I read its interaction list with genuine caution because of how fragile those patients already are. All 17 supplements on file act on absorption through the gut,…”

Reviewed by 2 · Jul 18, 2026

Open the Palifermin interaction page

One more smart check

Taking Reed Herb as Part of a Dietary Supplement Product? Check It for Interactions

We hold 57 real supplement products containing Reed Herb, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Reed Herb. Even though Reed Herb itself has no known interaction with Palifermin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Reed Herb and Palifermin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Reed Herb

Steady interest

#1,086 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Palifermin

Steady interest

#2,659 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Reed Herb is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Reed Herb reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Reed Herb and Palifermin records this page draws on were last updated June 20, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Reed Herb

What is Reed Herb?

Digestive upset
Nausea and vomiting
Diuretic (increasing urine)
Promoting sweating during fevers
Clearing heat (traditional use)

Reed herb (Phragmites australis) is a tall grass whose stems and roots have long been used in traditional medicine, especially for digestive complaints, fever, and as a mild diuretic. Modern scientific evidence in people is very limited, so its benefits are not well proven. If you want to try it, talk with a pharmacist or doctor first, and avoid it during pregnancy and breastfeeding due to a lack of safety data.

Phragmites australis · Poaceae · Stem and rhizome (root) · Tea, decoction, dried herb, powder

An interaction check asks whether these two react with each other — it does not ask whether Reed Herb is a good idea for someone in your situation. Here is what our Reed Herb record says about it on its own.

Reed Herb: dosing

There is no standardized, well-established dose for reed herb. Traditional preparations are usually made as a decoction or tea from the dried stem or rhizome, but the right amount can vary widely.If you choose to use a commercial product, follow the directions on the label and do not take more than recommended.

From our Reed Herb monograph — the full record covers uses, side effects and every documented interaction.

Read the full Reed Herb monograph & all interactions

Medication

About Palifermin

What Is Palifermin Used For?

Brand name: Kepivance

Kepivance (palifermin) is used to decrease how often and how long severe oral mucositis — painful sores in the mouth and throat — occurs in patients with hematologic malignancies (blood cancers such as lymphoma, leukemia, or multiple myeloma) who are receiving high-dose, cell-damaging (myelotoxic) therapy before an autologous hematopoietic stem cell transplant (a transplant using the patient's own stem cells).

Kepivance is specifically indicated when the preparative chemotherapy or radiation regimen is expected to cause severe mucositis in most patients. It is not recommended for use with a high-dose melphalan conditioning regimen, and it was not found to be effective in the setting of allogeneic stem cell transplant (using a donor's cells). Its safety and effectiveness have not been established for patients with non-blood cancers (non-hematologic malignancies).

Most-Reported Side Effects for Palifermin

From FAERS, the FDA’s public side-effect reporting system (388 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Mucosal inflammation 56 reports

Febrile neutropenia 39 reports

Rash 39 reports

Stomatitis 34 reports

Erythema 28 reports

See full Palifermin drug information

Keep checking

Other Drugs & Reed Herb

Browse every other medication we’ve checked against Reed Herb — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

0Moderate

0Minor

2,829No known interaction

2,829 No interaction

No interaction 2,829 drugs checked — show the list

We also checked Reed Herb against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Reed Herb list.

See the full Reed Herb interactions page

See every supplement checked against Palifermin, ranked by severity

Evidence & sources

Reed Herb References

The 2 sources that drive our Reed Herb monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Reed Herb is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

Herbs at a Glance — NIH NCCIH Source
Herbs and Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Reed Herb and Palifermin Together: Common Questions

Is it safe to take Reed Herb with Palifermin?

We do not list a known interaction between Reed Herb and Palifermin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Are Reed Herb and Palifermin used for the same thing?

They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Reed Herb in each. That is a conversation for your prescriber, especially if Palifermin is being adjusted to a target.

Does Palifermin interact with any supplements?

Yes. Palifermin has documented interactions with 17 supplements in our database — Reed Herb is not one of them. The Palifermin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Reed Herb monograph Uses, safety profile, and every drug interaction in one place Palifermin drug information The full plain-English guide to this medication Palifermin supplement interactions Every supplement checked against Palifermin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Palifermin and Reed Herb?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.