Saw Palmetto - Viagra (Sildenafil Citrate) Interaction

Interaction Details

Pharmacist Analysis

There are no known interactions between Viagra and saw palmetto. The two medications have different mechanisms of action and do not act on the same biochemical pathways.

Saw palmetto blocks the conversion of testosterone to DHT, while Viagra inhibits PDE5. They are also not known to affect the metabolism of the other or have additive adverse effects.

Interestingly, there is a combination prescription medication called "Entadfi," which combines tadalafil (the same class of medication as Viagra) with finasteride (which has a similar mechanism of action to saw palmetto) for the treatment of BPH.

While Viagra (sildenafil) is not FDA-approved to treat BPH, it has the same mechanism of action as tadalafil. Saw palmetto likely works, at least in part, by blocking the conversion of testosterone to DHT, therefore, it is somewhat analogous to compare the combination of Viagra and saw palmetto to the combination of tadalafil and finasteride (which, again, is available by prescription as Entadfi.

So, overall, there is currently no evidence to suggest that there is an interaction between Viagra and saw palmetto. They may even have beneficial effects when combined.

However, patients should always consult with their doctor before taking any new medication, including natural supplements, to ensure that there are no potential interactions or adverse effects.

There are no known interactions between Viagra and saw palmetto. The two medications have different mechanisms of action and do not act on the same biochemical pathways.

Saw palmetto blocks the conversion of testosterone to DHT, while Viagra inhibits PDE5. They are also not known to affect the metabolism of the other or have additive adverse effects.

Interestingly, there is a combination prescription medication called "Entadfi," which combines tadalafil (the same class of medication as Viagra) with finasteride (which has a similar mechanism of action to saw palmetto) for the treatment of BPH.

While Viagra (sildenafil) is not FDA-approved to treat BPH, it has the same mechanism of action as tadalafil. Saw palmetto likely works, at least in part, by blocking the conversion of testosterone to DHT, therefore, it is somewhat analogous to compare the combination of Viagra and saw palmetto to the combination of tadalafil and finasteride (which, again, is available by prescription as Entadfi.

So, overall, there is currently no evidence to suggest that there is an interaction between Viagra and saw palmetto. They may even have beneficial effects when combined.

However, patients should always consult with their doctor before taking any new medication, including natural supplements, to ensure that there are no potential interactions or adverse effects.

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On the whole, saw palmetto has very few reported drug interactions due to its lack of effects on liver metabolizing enzymes (e.g., CYP P450 enzymes).

There have been some reports of minor interactions with anticoagulants, estrogens, and contraceptives due to saw palmetto's purported effects on blood clotting and various hormones in the body. However, these interactions have generally only been seen in lab studies and for most individuals, are not considered clinically significant.

As always, however, be sure to talk to your doctor before starting any new medications or supplements so you can be appropriately monitored.

There are no known interactions between Viagra and saw palmetto. The two medications have different mechanisms of action and do not act on the same biochemical pathways.

Saw palmetto blocks the conversion of testosterone to DHT, while Viagra inhibits PDE5. They are also not known to affect the metabolism of the other or have additive adverse effects.

Interestingly, there is a combination prescription medication called "Entadfi," which combines tadalafil (the same class of medication as Viagra) with finasteride (which has a similar mechanism of action to saw palmetto) for the treatment of BPH.

While Viagra (sildenafil) is not FDA-approved to treat BPH, it has the same mechanism of action as tadalafil. Saw palmetto likely works, at least in part, by blocking the conversion of testosterone to DHT, therefore, it is somewhat analogous to compare the combination of Viagra and saw palmetto to the combination of tadalafil and finasteride (which, again, is available by prescription as Entadfi.

So, overall, there is currently no evidence to suggest that there is an interaction between Viagra and saw palmetto. They may even have beneficial effects when combined.

However, patients should always consult with their doctor before taking any new medication, including natural supplements, to ensure that there are no potential interactions or adverse effects.

Comprehensive analysis does not indicate a significant interaction.

There are no known interactions between Viagra and saw palmetto. The two medications have different mechanisms of action and do not act on the same biochemical pathways.

Saw palmetto blocks the conversion of testosterone to DHT, while Viagra inhibits PDE5. They are also not known to affect the metabolism of the other or have additive adverse effects.

Interestingly, there is a combination prescription medication called "Entadfi," which combines tadalafil (the same class of medication as Viagra) with finasteride (which has a similar mechanism of action to saw palmetto) for the treatment of BPH.

While Viagra (sildenafil) is not FDA-approved to treat BPH, it has the same mechanism of action as tadalafil. Saw palmetto likely works, at least in part, by blocking the conversion of testosterone to DHT, therefore, it is somewhat analogous to compare the combination of Viagra and saw palmetto to the combination of tadalafil and finasteride (which, again, is available by prescription as Entadfi.

So, overall, there is currently no evidence to suggest that there is an interaction between Viagra and saw palmetto. They may even have beneficial effects when combined.

However, patients should always consult with their doctor before taking any new medication, including natural supplements, to ensure that there are no potential interactions or adverse effects.

Sildenafil Citrate Overview

• Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults and children 1 year of age and older with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily.

• If you are taking sildenafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire. Sildenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).

Saw Palmetto - More Interactions

Saw Palmetto interacts with 173 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.