Securinega Suffruticosa - Guaifenesin, Pseudoephedrine Interaction
Herbal: Securinega Suffruticosa
Drug: Guaifenesin, Pseudoephedrine
Brand names:
Deconsal II, Panmist LA, Entex PSE, Glycofed, Aquabid D, Duratuss, Guai-Vent/PSE, Nasabid SR, Iotex PSE, Guaifed PSE, Zephrex LA, Guaifen PSE, Ru-Tuss DE, Quaifen PSE, Guaitex PSE, Ami-tex PSE, Med Rx, Iosal II, D Feda II, Respa 1st, Desal II, Defen LA, Decongest II, Syn Rx, Deconsal LA, Profen II, Profen Forte, Medent LD, Panmist Jr, Histalet X, Touro LA, Nasatab LA, Guaitab, Congestac, Maxifed G, Maxifed, H 9600 SR, Cephadyn, Aquatab D, Despec SR
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 18, 2025
Interaction Details
Guaifenesin, Pseudoephedrine is classified as belonging to the following category: Stimulant Drugs
Theoretically, taking Securinega suffruticosa with stimulant drugs might increase the risk of serious adverse effects.
Securinega suffruticosa contains the alkaloid securinine. Animal research shows that securinine has CNS stimulating effects.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Holmes M, Crater AK, Dhudshia B, Thadani AN, Ananvoranich S. Toxoplasma gondii: inhibitory activity and encystation effect of securinine and pyrrolidine derivatives on Toxoplasma growth. Exp Parasitol. 2011;127(2):370-5.
- Raj D, Luczkiewicz M. Securinega suffruticosa. Fitoterapia. 2008;79(6):419-27.
Securinega Suffruticosa - More Interactions
Securinega Suffruticosa interacts with 171 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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