Sorrel - Toprol XL (Metoprolol) Interaction
Herbal: Sorrel
Also Known As: Rumex acetosa, Acedera, Azeda-Brava, Common Sorrel, Field Sorrel, Garden Sorrel, Oseille, Oseille Commune, Petite Oseille, Red Sorrel, Sheep Sorrel, Sheep's Sorrel, Sorrel Dock, Sour Dock, Surette, Wiesensauerampfer
Drug: Metoprolol
Brand names:
Lopressor, Toprol XL
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 20, 2025
Interaction Details
There were no interactions found between Metoprolol and Sorrel. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pharmacist Analysis
Sorrel has few documented, clinically significant, drug interactions. Preliminary research in animals indicates it may interact with antiplatelet drugs and drugs that are a substrate for transporter proteins known as OATPs (Organic Anion Transporting Polypeptides).
It is unlikely sorrel has clinically significant drug interactions, and there is no known drug interaction between the drug in this monograph and sorrel. As always however, be sure to let your doctor know about all the medications you are taking so you can be appropriately monitored.
- Dr. Brian Staiger, PharmDSorrel Overview
Sorrel is a perennial herb that is known for its distinct sour taste. It grows in temperate climates all over the world, and is often used in cooking to add a tangy flavor to dishes. The sour flavor of sorrel is due to the presence of oxalate, a compound found in many plants. In addition to its culinary uses, sorrel has also been used in traditional medicine for a variety of purposes, such as treating fever, inflammation, and skin conditions. Sorrel has been utilized for its potential health benefits, which may include antioxidant, anti-inflammatory, and antimicrobial properties. It is worth noting, however, that sorrel should be used in moderation, as the high levels of oxalate it contains can lead to the formation of kidney stones in some people.
Metoprolol Overview
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Metoprolol is used alone or in combination with other medications to treat high blood pressure. It also is used to treat chronic (long-term) angina (chest pain). Metoprolol is also used to improve survival after a heart attack. Metoprolol also is used in combination with other medications to treat heart failure. Metoprolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.
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High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
Sorrel - More Interactions
Sorrel interacts with 166 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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