Drug & supplement interaction

Sweet Cicely + Erlotinib

Erlotinib brand name: Tarceva.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Sweet Cicely and Erlotinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Erlotinib states a food rule worth keeping to.

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Interaction report

Sweet Cicely and Erlotinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Erlotinib and Sweet Cicely in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Sweet Cicely at all — not against Erlotinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Sweet Cicely safety at a glance

Sweet Cicely overall Use caution Likely safe in small culinary amounts, but medicinal use is poorly studied.
Pregnancy Avoid Not enough safety data, so it is best avoided in medicinal amounts during pregnancy.
Breastfeeding Avoid Safety has not been studied, so avoid medicinal use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Erlotinib and Sweet Cicely? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Erlotinib’s Own FDA Label Lists

This is not an interaction — none of it involves Sweet Cicely. These are the most notable effects listed in the ADVERSE REACTIONS section of Erlotinib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A stroke or mini-stroke Worth acting on
  • A bowel blockage Worth acting on
  • Severe muscle breakdown Worth acting on
  • Muscle weakness Worth acting on
  • Bleeding in the gut Worth acting on
  • A heart attack Worth acting on
  • Blood clots Worth acting on
  • Pancreatitis Worth acting on
  • Fainting Worth acting on
  • A severe skin reaction Worth acting on

Showing the 10 most notable of 39 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Erlotinib. Read the label on DailyMed › Where a percentage is shown, it is the share of 12,442 voluntary FDA FAERS reports for Erlotinib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Sweet Cicely’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Sweet Cicely side to compare — that is a limit of the record, not a statement that Sweet Cicely has no side effects.

How to take them

Some Erlotinib Products Have a Food Rule — Sweet Cicely Should Not Break It

At least one FDA label for a product containing Erlotinib says to take it on an empty stomach. Most supplements — Sweet Cicely included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Erlotinib on its own and move Sweet Cicely to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Erlotinib products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Recommended Dose – NSCLC The recommended daily dose of erlotinib tablets for NSCLC is 150 mg taken on an empty stomach, i.e., at least one hour before or two hours after the ingestion of food.

From the Dosage and Administration section of the FDA label we read for Erlotinib — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Erlotinib

This page covers Sweet Cicely only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Erlotinib page lists 18 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Bilberry (moderate), Coffee Charcoal (moderate), European Mandrake (moderate) and Glucomannan (moderate).

By severity: 1 major · 8 moderate · 9 minor.

From our pharmacist’s overview on the Erlotinib page

“Activated charcoal is the entry I would flag first for anyone taking erlotinib (Tarceva), an oral targeted therapy for certain lung cancers. Charcoal can adsorb the drug in the gut and cut how much reaches the bloodstream, and with a cancer pill, less absorbed means less cancer fought.”

Reviewed by 2 · Jul 18, 2026

Open the Erlotinib interaction page

How much people look this up

Where Sweet Cicely and Erlotinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Sweet Cicely
Steady interest

#1,404 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Erlotinib
Steady interest

#2,520 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Sweet Cicely and Erlotinib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Sweet Cicely

What is Sweet Cicely?

  • Digestive upset and gas
  • Mild cough and chest complaints
  • As a natural sweetener for tart foods
  • Loss of appetite
  • General tonic

Sweet Cicely is a mild, anise-flavored garden herb traditionally used in cooking and folk remedies for digestion and coughs. There is very little modern scientific research to confirm any health benefits, but it is generally considered safe in food amounts. Talk to a pharmacist or doctor before using it as a medicine, especially if you are pregnant or breastfeeding.

Myrrhis odorata · Apiaceae · Leaves, seeds, and roots · Fresh or dried herb, tea, culinary herb, occasionally tincture

An interaction check asks whether these two react with each other — it does not ask whether Sweet Cicely is a good idea for someone in your situation. Here is what our Sweet Cicely record says about it on its own.

Sweet Cicely: dosing

There is no established, standardized medicinal dose for Sweet Cicely. Most use is culinary, where the fresh or dried leaves and seeds are added to food or steeped as a mild tea.If you choose to use a commercial Sweet Cicely product, follow the directions on the product label and do not exceed the recommended amount.

From our Sweet Cicely monograph — the full record covers uses, side effects and every documented interaction.

Read the full Sweet Cicely monograph & all interactions
Medication

About Erlotinib

What Is Erlotinib Used For?

Brand name: Tarceva

Erlotinib tablets are used to treat metastatic non-small cell lung cancer (NSCLC) in patients whose tumors carry specific gene changes — EGFR exon 19 deletions or exon 21 (L858R) mutations — confirmed by an FDA-approved test. It can be used as a first-line treatment, as maintenance therapy, or after at least one prior chemotherapy has stopped working.

Erlotinib tablets are also used for the first-line treatment of locally advanced, unresectable, or metastatic pancreatic cancer — but only in combination with another chemotherapy drug called gemcitabine. Erlotinib is not recommended alongside platinum-based chemotherapy regimens.

Most-Reported Side Effects for Erlotinib

From FAERS, the FDA’s public side-effect reporting system (12,441 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 1,339 reports
Rash 1,317 reports
Malignant neoplasm progression 890 reports
Fatigue 718 reports
Nausea 696 reports
See full Erlotinib drug information
Keep checking

Other Drugs & Sweet Cicely

Browse every other medication we’ve checked against Sweet Cicely — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Sources

Sources & How We Checked

We checked Sweet Cicely against Erlotinib in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Sweet Cicely and Erlotinib Together: Common Questions

Is it safe to take Sweet Cicely with Erlotinib?
We do not list a known interaction between Sweet Cicely and Erlotinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Sweet Cicely and Erlotinib at the same time of day?
At least one FDA label for a product containing Erlotinib says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Erlotinib on its own and move Sweet Cicely to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Erlotinib interact with any supplements?
Yes. Erlotinib has documented interactions with 18 supplements in our database — Sweet Cicely is not one of them. The Erlotinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Erlotinib and Sweet Cicely?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.