Erlotinib

Erlotinib is used to treat certain types of non-small cell lung cancer that has spread to nearby tissues or to other parts of the body in patients who have already been treated with at least one other chemotherapy medication and have not gotten better. Erlotinib is also used in combination with another medication (gemcitabine [Gemzar]) to treat pancreatic cancer that has spread to nearby tissues or to other parts of the body and cannot be treated with surgery. Erlotinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.

Erlotinib comes as a tablet to take by mouth. It is usually taken on an empty stomach once a day, at least 1 hour before or 2 hours after eating a meal or snack. Take erlotinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take erlotinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may decrease your dose of erlotinib during your treatment. This depends on how well the medication works for you and the side effects you experience. Talk to your doctor about how you are feeling during your treatment. Continue to take erlotinib even if you feel well. Do not stop taking erlotinib without talking to your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking erlotinib,

• tell your doctor and pharmacist if you are allergic to erlotinib, any other medications, or any of the ingredients in erlotinib tablets. Ask your pharmacist for a list of the ingredients.

• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: angiogenesis inhibitors such as bevacizumab (Avastin); anticoagulants ('blood thinners') such as warfarin (Coumadin); certain antifungals such as itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), and voriconazole (Vfend); boceprevir (Victrelis); carbamazepine (Tegretol); ciprofloxacin (Cipro, Proquin XR); clarithromycin (Biaxin); conivaptan (Vaprisol); HIV protease inhibitors such as atazanavir (Reyataz), indinavir (Crixivan), lopinavir/ritonavir (Kaletra), nelfinavir (Viracept), ritonavir (Norvir), and saquinavir (Fortovase, Invirase); H₂ blockers such as cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), and ranitidine (Zantac); medications for acne such as benzoyl peroxide (in Epiduo, in BenzaClin, in Benzamycin, others); midazolam (Versed): nefazodone; nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); phenobarbital (Luminal, Solfoton); phenytoin (Dilantin); proton pump inhibitors such as esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), and rabeprazole (AcipHex); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); rifapentine; taxane medications for cancer such as docetaxel (Taxotere) and paclitaxel (Abraxane, Taxol); telithromycin (Ketek); teriflunomide (Aubagio); and troleandomycin (TAO) (not available in the U.S.). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with erlotinib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

• if you are taking antacids, take them several hours before or several hours after you take erlotinib.

• tell your doctor what herbal products you are taking, especially St. John's wort.

• tell your doctor if you are being treated or have recently been treated with chemotherapy or radiation therapy (treatment for cancer that uses waves of high energy particles to kill cancer cells). Also tell your doctor if you have or have ever had lung disease or infection, stomach ulcers, diverticular disease (condition in which abnormal pouches form in the large intestine and may become inflamed), or liver or kidney disease.

• tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are taking erlotinib and for at least 1 month after your final dose. Talk to your doctor about birth control methods that you can use. If you become pregnant, call your doctor immediately. Erlotinib may harm the fetus.

• tell your doctor if you are breastfeeding. You should not breastfeed during your treatment with erlotinib and for up to 2 weeks after your final dose.

• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking erlotinib.

• tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of this medication.

• plan to avoid unnecessary or prolonged exposure to sunlight and to wear a hat, other protective clothing, sunglasses, and sunscreen. Choose a sunscreen that has a sun protection factor (SPF) of at least 15 and contains zinc oxide or titanium dioxide. Exposure to sunlight increases the risk that you will develop a rash during your treatment with erlotinib.

• you should know that erlotinib may cause rashes and other skin problems. To protect your skin, use a mild alcohol-free moisturizer, wash your skin with mild soap, and remove cosmetics with a mild cleanser.

Avoid eating grapefruit and drinking grapefruit juice while taking this medicine.

To prevent diarrhea that may be caused by erlotinib, drink small sips of a liquid such as a sugar-free sports drink often throughout the day, eat mild foods such as crackers and toast, and avoid spicy foods.

Take the next dose at your regular time the next day. Do not take a double dose to make up for a missed one.

• Erlotinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • diarrhea

  • loss of appetite

  • nausea

  • vomiting

  • heartburn

  • gas

  • constipation

  • mouth sores

  • weight loss

  • extreme tiredness

  • headache

  • bone or muscle pain

  • depression

  • anxiety

  • numbness, burning, or tingling of the hands or feet

  • swelling of the arms, hands, feet, ankles, or lower legs

  • darkening of skin

  • hair loss

  • changes in the appearance of the hair and nails

• Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

  • rash (may look like acne and may affect the skin on the face, upper chest, or back)

  • blistering, peeling, dry, or cracked skin

  • itching, tenderness, or burning of the skin

  • shortness of breath

  • cough

  • fever or chills

  • growth of eyelashes on the inside of the eyelid

  • severe stomach pain

  • dry, red, painful, teary, or irritated eyes

  • blurred vision

  • eye sensitivity to light

  • chest pain or pressure

  • pain in the arms, neck, or upper back

  • rapid, irregular, or pounding heartbeat

  • slow or difficult speech

  • dizziness or faintness

  • weakness or numbness of an arm or leg

  • unusual bruising or bleeding

  • black and tarry or bloody stools

  • vomit that is bloody or looks like coffee grounds

  • sunken eyes

  • dry mouth

  • decreased urination

  • dark urine

  • pale or yellow skin

  • redness, warmth, pain, tenderness, or swelling in one leg

• Erlotinib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

• diarrhea

• rash

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to erlotinib.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug	Interaction
Moxifloxacin	Moxifloxacin The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Erlotinib.
Repaglinide	Repaglinide The metabolism of Repaglinide can be decreased when combined with Erlotinib.
Montelukast	Montelukast The metabolism of Erlotinib can be decreased when combined with Montelukast.
Insulin Glargine (rDNA origin) Injection	Insulin Glargine (rDNA origin) Injection The metabolism of Erlotinib can be increased when combined with Insulin glargine.
Leflunomide	Leflunomide The serum concentration of Erlotinib can be decreased when it is combined with Leflunomide.
Delavirdine	Delavirdine The metabolism of Erlotinib can be decreased when combined with Delavirdine.
Nevirapine	Nevirapine The metabolism of Erlotinib can be decreased when combined with Nevirapine.
Atorvastatin	Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Erlotinib.
Dolasetron	Dolasetron The metabolism of Erlotinib can be decreased when combined with Dolasetron.
Aminophylline	Aminophylline The metabolism of Aminophylline can be decreased when combined with Erlotinib.
Anagrelide	Anagrelide The risk or severity of QTc prolongation can be increased when Anagrelide is combined with Erlotinib.
Calcium Carbonate	Calcium Carbonate Calcium carbonate can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Candesartan	Candesartan The metabolism of Erlotinib can be decreased when combined with Candesartan.
Cilostazol	Cilostazol The metabolism of Cilostazol can be decreased when combined with Erlotinib.
Clopidogrel	Clopidogrel The metabolism of Erlotinib can be decreased when combined with Clopidogrel.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The metabolism of Erlotinib can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) The metabolism of Conjugated estrogens can be decreased when combined with Erlotinib.
Fenofibrate	Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Erlotinib.
Magnesium Hydroxide	Magnesium Hydroxide Magnesium hydroxide can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Magnesium Oxide	Magnesium Oxide Magnesium oxide can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Methylergonovine	Methylergonovine The metabolism of Erlotinib can be decreased when combined with Methylergometrine.
Mycophenolate	Mycophenolate The metabolism of Mycophenolic acid can be decreased when combined with Erlotinib.
Paregoric	Paregoric The metabolism of Morphine can be decreased when combined with Erlotinib.
Penbutolol	Penbutolol The metabolism of Erlotinib can be decreased when combined with Acebutolol.
Ranitidine	Ranitidine Ranitidine can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Reserpine	Reserpine The metabolism of Erlotinib can be increased when combined with Reserpine.
Sumatriptan	Sumatriptan Erlotinib may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus	Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Erlotinib.
Tizanidine	Tizanidine The metabolism of Erlotinib can be decreased when combined with Tizanidine.
Triamcinolone	Triamcinolone The serum concentration of Erlotinib can be decreased when it is combined with Triamcinolone.
Zolmitriptan	Zolmitriptan The metabolism of Erlotinib can be decreased when combined with Zolmitriptan.
Doxycycline Injection	Doxycycline Injection The metabolism of Erlotinib can be decreased when combined with Doxycycline.
Famotidine Injection	Famotidine Injection Famotidine can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Fluconazole Injection	Fluconazole Injection The metabolism of Erlotinib can be decreased when combined with Fluconazole.
Foscarnet Injection	Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Erlotinib.
Interferon Beta-1b Injection	Interferon Beta-1b Injection The metabolism of Erlotinib can be decreased when combined with Interferon beta-1b.
Interferon Gamma-1b Injection	Interferon Gamma-1b Injection The metabolism of Erlotinib can be decreased when combined with Interferon gamma-1b.
Levofloxacin Injection	Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Levofloxacin is combined with Erlotinib.
Meperidine Injection	Meperidine Injection The serum concentration of Erlotinib can be decreased when it is combined with Meperidine.
Methylprednisolone Injection	Methylprednisolone Injection The serum concentration of Erlotinib can be decreased when it is combined with Methylprednisolone.
Metoclopramide Injection	Metoclopramide Injection The metabolism of Erlotinib can be decreased when combined with Metoclopramide.
Metronidazole Injection	Metronidazole Injection The metabolism of Erlotinib can be decreased when combined with Metronidazole.
Morphine Injection	Morphine Injection The metabolism of Morphine can be decreased when combined with Erlotinib.
Zidovudine Injection	Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Erlotinib.
Altretamine	Altretamine The metabolism of Erlotinib can be decreased when combined with Amphetamine.
Cyclosporine	Cyclosporine The metabolism of Erlotinib can be decreased when combined with Cyclosporine.
Ondansetron	Ondansetron The metabolism of Erlotinib can be decreased when combined with Ondansetron.
Granisetron	Granisetron The risk or severity of QTc prolongation can be increased when Granisetron is combined with Erlotinib.
Torsemide	Torsemide The metabolism of Torasemide can be decreased when combined with Erlotinib.
Olanzapine	Olanzapine Olanzapine can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Alosetron	Alosetron The metabolism of Erlotinib can be decreased when combined with Alosetron.
Dofetilide	Dofetilide The metabolism of Dofetilide can be decreased when combined with Erlotinib.
Entacapone	Entacapone The metabolism of Erlotinib can be decreased when combined with Entacapone.
Hydroxychloroquine	Hydroxychloroquine The metabolism of Erlotinib can be decreased when combined with Hydroxychloroquine.
Orlistat	Orlistat The serum concentration of Erlotinib can be decreased when it is combined with Orlistat.
Oxcarbazepine	Oxcarbazepine The serum concentration of Erlotinib can be decreased when it is combined with Oxcarbazepine.
Pantoprazole	Pantoprazole Erlotinib can cause a decrease in the absorption of Pantoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Zaleplon	Zaleplon The metabolism of Zaleplon can be decreased when combined with Erlotinib.
Anakinra	Anakinra The metabolism of Erlotinib can be increased when combined with Anakinra.
Desloratadine	Desloratadine The risk or severity of QTc prolongation can be increased when Desloratadine is combined with Erlotinib.
Trimipramine	Trimipramine The metabolism of Erlotinib can be decreased when combined with Trimipramine.
Etanercept Injection	Etanercept Injection The metabolism of Erlotinib can be increased when combined with Etanercept.
Modafinil	Modafinil The serum concentration of Erlotinib can be decreased when it is combined with Modafinil.
Tenofovir	Tenofovir The metabolism of Tenofovir can be decreased when combined with Erlotinib.
Sirolimus	Sirolimus The metabolism of Sirolimus can be decreased when combined with Erlotinib.
Dutasteride	Dutasteride The metabolism of Dutasteride can be decreased when combined with Erlotinib.
Epinephrine Injection	Epinephrine Injection The metabolism of Erlotinib can be decreased when combined with Epinephrine.
Eplerenone	Eplerenone The metabolism of Eplerenone can be decreased when combined with Erlotinib.
Escitalopram	Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Erlotinib.
Zonisamide	Zonisamide The metabolism of Erlotinib can be decreased when combined with Zonisamide.
Adalimumab Injection	Adalimumab Injection The metabolism of Erlotinib can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Erlotinib.
Atomoxetine	Atomoxetine The metabolism of Erlotinib can be decreased when combined with Atomoxetine.
Ezetimibe	Ezetimibe The metabolism of Ezetimibe can be decreased when combined with Erlotinib.
Teriparatide Injection	Teriparatide Injection The therapeutic efficacy of Teriparatide can be decreased when used in combination with Erlotinib.
Atazanavir	Atazanavir The metabolism of Erlotinib can be decreased when combined with Atazanavir.
Almotriptan	Almotriptan The metabolism of Almotriptan can be decreased when combined with Erlotinib.
Eletriptan	Eletriptan The metabolism of Erlotinib can be decreased when combined with Eletriptan.
Mefloquine	Mefloquine The metabolism of Erlotinib can be decreased when combined with Mefloquine.
Rosuvastatin	Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Erlotinib.
Vardenafil	Vardenafil The metabolism of Vardenafil can be decreased when combined with Erlotinib.
Alfuzosin	Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Erlotinib.
Aprepitant	Aprepitant The metabolism of Erlotinib can be decreased when combined with Aprepitant.
Interferon Beta-1a Subcutaneous Injection	Interferon Beta-1a Subcutaneous Injection The metabolism of Erlotinib can be decreased when combined with Interferon beta-1a.
Tegaserod	Tegaserod The metabolism of Erlotinib can be decreased when combined with Tegaserod.
Tadalafil	Tadalafil The metabolism of Tadalafil can be decreased when combined with Erlotinib.
Frovatriptan	Frovatriptan The metabolism of Frovatriptan can be decreased when combined with Erlotinib.
Gemifloxacin	Gemifloxacin The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Erlotinib.
Progesterone	Progesterone The serum concentration of Erlotinib can be decreased when it is combined with Progesterone.
Apomorphine Injection	Apomorphine Injection The metabolism of Erlotinib can be decreased when combined with Apomorphine.
Darbepoetin Alfa Injection	Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Erlotinib.
Infliximab Injection	Infliximab Injection The metabolism of Erlotinib can be increased when combined with Infliximab.
Protriptyline	Protriptyline The metabolism of Erlotinib can be decreased when combined with Protriptyline.
Rifaximin	Rifaximin The serum concentration of Erlotinib can be decreased when it is combined with Rifaximin.
Duloxetine	Duloxetine The metabolism of Erlotinib can be decreased when combined with Duloxetine.
Norethindrone	Norethindrone The metabolism of Norethisterone can be decreased when combined with Erlotinib.
Trospium	Trospium The metabolism of Erlotinib can be decreased when combined with Trospium.
Bosentan	Bosentan The serum concentration of Erlotinib can be decreased when it is combined with Bosentan.
Cinacalcet	Cinacalcet The metabolism of Erlotinib can be decreased when combined with Cinacalcet.
Eszopiclone	Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Erlotinib.
Solifenacin	Solifenacin The metabolism of Erlotinib can be decreased when combined with Solifenacin.
Voriconazole	Voriconazole The metabolism of Erlotinib can be decreased when combined with Voriconazole.
Dextroamphetamine	Dextroamphetamine The metabolism of Erlotinib can be decreased when combined with Amphetamine.
Entecavir	Entecavir The metabolism of Erlotinib can be decreased when combined with Entecavir.
Peginterferon Alfa-2a Injection	Peginterferon Alfa-2a Injection The metabolism of Erlotinib can be decreased when combined with Peginterferon alfa-2a.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Erlotinib can be increased when it is combined with Peginterferon alfa-2b.
Ibandronate	Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Erlotinib.
Ramelteon	Ramelteon The metabolism of Ramelteon can be decreased when combined with Erlotinib.
Darifenacin	Darifenacin The metabolism of Darifenacin can be decreased when combined with Erlotinib.
Fentanyl	Fentanyl The metabolism of Fentanyl can be decreased when combined with Erlotinib.
Pregabalin	Pregabalin The risk or severity of QTc prolongation can be increased when Pregabalin is combined with Erlotinib.
Deferasirox	Deferasirox The serum concentration of Erlotinib can be decreased when it is combined with Deferasirox.
Phenylephrine	Phenylephrine The metabolism of Erlotinib can be increased when combined with Phenylephrine.
Tipranavir	Tipranavir The metabolism of Tipranavir can be decreased when combined with Erlotinib.
Felbamate	Felbamate The serum concentration of Erlotinib can be decreased when it is combined with Felbamate.
Ranolazine	Ranolazine The serum concentration of Erlotinib can be increased when it is combined with Ranolazine.
Abatacept Injection	Abatacept Injection The metabolism of Erlotinib can be increased when combined with Abatacept.
Rasagiline	Rasagiline The metabolism of Rasagiline can be decreased when combined with Erlotinib.
Imatinib	Imatinib The metabolism of Imatinib can be decreased when combined with Erlotinib.
Sitagliptin	Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Erlotinib.
Gefitinib	Gefitinib The metabolism of Gefitinib can be decreased when combined with Erlotinib.
Albuterol	Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Erlotinib.
Paliperidone	Paliperidone The metabolism of Paliperidone can be decreased when combined with Erlotinib.
Bortezomib	Bortezomib The metabolism of Erlotinib can be decreased when combined with Bortezomib.
Clofarabine Injection	Clofarabine Injection Erlotinib may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Fulvestrant Injection	Fulvestrant Injection The metabolism of Fulvestrant can be decreased when combined with Erlotinib.
Insulin Glulisine (rDNA origin) Injection	Insulin Glulisine (rDNA origin) Injection The metabolism of Erlotinib can be increased when combined with Insulin glulisine.
Oxaliplatin Injection	Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Oxaliplatin is combined with Erlotinib.
Posaconazole	Posaconazole The metabolism of Erlotinib can be decreased when combined with Posaconazole.
Primaquine	Primaquine The metabolism of Erlotinib can be decreased when combined with Primaquine.
Darunavir	Darunavir The serum concentration of Darunavir can be increased when it is combined with Erlotinib.
Pemetrexed Injection	Pemetrexed Injection The metabolism of Pemetrexed can be decreased when combined with Erlotinib.
Dimenhydrinate	Dimenhydrinate The risk or severity of QTc prolongation can be increased when Dimenhydrinate is combined with Erlotinib.
Lisdexamfetamine	Lisdexamfetamine The metabolism of Erlotinib can be decreased when combined with Lisdexamfetamine.
Nabilone	Nabilone The metabolism of Erlotinib can be decreased when combined with Nabilone.
Retapamulin	Retapamulin The metabolism of Retapamulin can be decreased when combined with Erlotinib.
Vorinostat	Vorinostat The risk or severity of QTc prolongation can be increased when Vorinostat is combined with Erlotinib.
Sorafenib	Sorafenib The metabolism of Erlotinib can be decreased when combined with Sorafenib.
Sunitinib	Sunitinib The metabolism of Erlotinib can be decreased when combined with Sunitinib.
Lapatinib	Lapatinib The metabolism of Lapatinib can be decreased when combined with Erlotinib.
Levocetirizine	Levocetirizine The risk or severity of QTc prolongation can be increased when Levocetirizine is combined with Erlotinib.
Dasatinib	Dasatinib The metabolism of Dasatinib can be decreased when combined with Erlotinib.
Mexiletine	Mexiletine The metabolism of Erlotinib can be decreased when combined with Mexiletine.
Armodafinil	Armodafinil The serum concentration of Erlotinib can be decreased when it is combined with Armodafinil.
Ivermectin	Ivermectin The metabolism of Ivermectin can be increased when combined with Erlotinib.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Erlotinib.
Nilotinib	Nilotinib The metabolism of Erlotinib can be decreased when combined with Nilotinib.
Toremifene	Toremifene The risk or severity of QTc prolongation can be increased when Erlotinib is combined with Toremifene.
Raltegravir	Raltegravir The metabolism of Raltegravir can be decreased when combined with Erlotinib.
Bexarotene	Bexarotene The serum concentration of Erlotinib can be decreased when it is combined with Bexarotene.
Budesonide	Budesonide The serum concentration of Erlotinib can be decreased when it is combined with Budesonide.
Chloramphenicol Injection	Chloramphenicol Injection The metabolism of Erlotinib can be decreased when combined with Chloramphenicol.
Etravirine	Etravirine The serum concentration of Erlotinib can be decreased when it is combined with Etravirine.
Arsenic Trioxide Injection	Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Erlotinib is combined with Arsenic trioxide.
Mitoxantrone Injection	Mitoxantrone Injection The metabolism of Mitoxantrone can be decreased when combined with Erlotinib.
Desvenlafaxine	Desvenlafaxine The metabolism of Erlotinib can be decreased when combined with Desvenlafaxine.
Cevimeline	Cevimeline The metabolism of Erlotinib can be decreased when combined with Cevimeline.
Nebivolol	Nebivolol The metabolism of Nebivolol can be decreased when combined with Erlotinib.
Tretinoin	Tretinoin The metabolism of Tretinoin can be decreased when combined with Erlotinib.
Bendamustine Injection	Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Erlotinib.
Pilocarpine	Pilocarpine The metabolism of Erlotinib can be decreased when combined with Pilocarpine.
Flecainide	Flecainide The metabolism of Flecainide can be decreased when combined with Erlotinib.
Certolizumab Injection	Certolizumab Injection The metabolism of Erlotinib can be increased when combined with Certolizumab pegol.
Ixabepilone Injection	Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Erlotinib.
Irinotecan Injection	Irinotecan Injection The risk or severity of neutropenia can be increased when Erlotinib is combined with Irinotecan.
Praziquantel	Praziquantel The metabolism of Praziquantel can be decreased when combined with Erlotinib.
Mitotane	Mitotane The metabolism of Erlotinib can be increased when combined with Mitotane.
Rufinamide	Rufinamide The serum concentration of Erlotinib can be decreased when it is combined with Rufinamide.
Midazolam	Midazolam The serum concentration of Midazolam can be increased when it is combined with Erlotinib.
Naltrexone Injection	Naltrexone Injection The metabolism of Naltrexone can be decreased when combined with Erlotinib.
Eltrombopag	Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Erlotinib.
Milnacipran	Milnacipran The metabolism of Erlotinib can be decreased when combined with Milnacipran.
Dexlansoprazole	Dexlansoprazole Erlotinib can cause a decrease in the absorption of Dexlansoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Fesoterodine	Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Erlotinib.
Degarelix Injection	Degarelix Injection The risk or severity of QTc prolongation can be increased when Degarelix is combined with Erlotinib.
Betaxolol	Betaxolol The metabolism of Erlotinib can be decreased when combined with Betaxolol.
Iloperidone	Iloperidone The metabolism of Iloperidone can be decreased when combined with Erlotinib.
Lacosamide	Lacosamide The metabolism of Lacosamide can be decreased when combined with Erlotinib.
Everolimus	Everolimus The metabolism of Everolimus can be decreased when combined with Erlotinib.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be decreased when combined with Erlotinib.
Dronedarone	Dronedarone Erlotinib may increase the QTc-prolonging activities of Dronedarone.
Pralatrexate Injection	Pralatrexate Injection Erlotinib may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection	Palonosetron Injection The metabolism of Erlotinib can be decreased when combined with Palonosetron.
Saxagliptin	Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Erlotinib.
Telavancin Injection	Telavancin Injection The risk or severity of QTc prolongation can be increased when Telavancin is combined with Erlotinib.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Erlotinib.
Tapentadol	Tapentadol The metabolism of Erlotinib can be decreased when combined with Tapentadol.
Topotecan	Topotecan The serum concentration of Erlotinib can be decreased when it is combined with Topotecan.
Golimumab Injection	Golimumab Injection The metabolism of Erlotinib can be increased when combined with Golimumab.
Pazopanib	Pazopanib The metabolism of Pazopanib can be decreased when combined with Erlotinib.
Asenapine	Asenapine Asenapine can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pitavastatin	Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Erlotinib.
Albendazole	Albendazole The metabolism of Albendazole can be decreased when combined with Erlotinib.
Levonorgestrel	Levonorgestrel The metabolism of Erlotinib can be decreased when combined with Levonorgestrel.
Oxymorphone	Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Erlotinib.
Tocilizumab Injection	Tocilizumab Injection The serum concentration of Erlotinib can be decreased when it is combined with Tocilizumab.
Eribulin Injection	Eribulin Injection The risk or severity of QTc prolongation can be increased when Eribulin is combined with Erlotinib.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Erlotinib.
Lurasidone	Lurasidone The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Erlotinib.
Acetaminophen Injection	Acetaminophen Injection The serum concentration of Erlotinib can be decreased when it is combined with Acetaminophen.
Vilazodone	Vilazodone The metabolism of Erlotinib can be decreased when combined with Vilazodone.
Denileukin Diftitox Injection	Denileukin Diftitox Injection The metabolism of Erlotinib can be decreased when combined with Aldesleukin.
Terbutaline Injection	Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Erlotinib.
Busulfan Injection	Busulfan Injection The metabolism of Busulfan can be decreased when combined with Erlotinib.
Roflumilast	Roflumilast The metabolism of Roflumilast can be decreased when combined with Erlotinib.
Linagliptin	Linagliptin The metabolism of Linagliptin can be decreased when combined with Erlotinib.
Rilpivirine	Rilpivirine The metabolism of Erlotinib can be decreased when combined with Rilpivirine.
Telaprevir	Telaprevir The metabolism of Glecaprevir can be decreased when combined with Erlotinib.
Potassium Iodide	Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Erlotinib.
Cyclophosphamide Injection	Cyclophosphamide Injection The serum concentration of Erlotinib can be decreased when it is combined with Cyclophosphamide.
Abiraterone	Abiraterone The serum concentration of Erlotinib can be increased when it is combined with Abiraterone.
Triptorelin Injection	Triptorelin Injection The risk or severity of QTc prolongation can be increased when Triptorelin is combined with Erlotinib.
Rivaroxaban	Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Erlotinib.
Ticagrelor	Ticagrelor The metabolism of Erlotinib can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection	Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Erlotinib.
Ruxolitinib	Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Erlotinib.
Vandetanib	Vandetanib The metabolism of Vandetanib can be decreased when combined with Erlotinib.
Clobazam	Clobazam The serum concentration of Erlotinib can be decreased when it is combined with Clobazam.
Vemurafenib	Vemurafenib The serum concentration of Erlotinib can be decreased when it is combined with Vemurafenib.
Vismodegib	Vismodegib The metabolism of Erlotinib can be decreased when combined with Vismodegib.
Ivacaftor	Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Erlotinib.
Axitinib	Axitinib The metabolism of Axitinib can be decreased when combined with Erlotinib.
Crizotinib	Crizotinib The metabolism of Erlotinib can be decreased when combined with Crizotinib.
Cabergoline	Cabergoline The metabolism of Erlotinib can be decreased when combined with Cabergoline.
Naloxone Injection	Naloxone Injection The metabolism of Naloxone can be decreased when combined with Erlotinib.
Ambrisentan	Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Erlotinib.
Ezogabine	Ezogabine The metabolism of Tiagabine can be decreased when combined with Erlotinib.
Enzalutamide	Enzalutamide The serum concentration of Enzalutamide can be increased when it is combined with Erlotinib.
Mirabegron	Mirabegron The serum concentration of Erlotinib can be increased when it is combined with Mirabegron.
Regorafenib	Regorafenib The metabolism of Erlotinib can be decreased when combined with Regorafenib.
Bosutinib	Bosutinib The metabolism of Erlotinib can be decreased when combined with Bosutinib.
Corticotropin, Repository Injection	Corticotropin, Repository Injection The serum concentration of Erlotinib can be decreased when it is combined with Corticotropin.
Teriflunomide	Teriflunomide The serum concentration of Erlotinib can be decreased when it is combined with Teriflunomide.
Cabozantinib (thyroid cancer)	Cabozantinib (thyroid cancer) The metabolism of Erlotinib can be decreased when combined with Cabozantinib.
Bedaquiline	Bedaquiline The risk or severity of QTc prolongation can be increased when Bedaquiline is combined with Erlotinib.
Tofacitinib	Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Erlotinib.
Alogliptin	Alogliptin The metabolism of Alogliptin can be decreased when combined with Erlotinib.
Ponatinib	Ponatinib The metabolism of Ponatinib can be decreased when combined with Erlotinib.
Pomalidomide	Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Erlotinib.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Erlotinib.
Apixaban	Apixaban The metabolism of Apixaban can be decreased when combined with Erlotinib.
Dabrafenib	Dabrafenib The serum concentration of Erlotinib can be decreased when it is combined with Dabrafenib.
Ospemifene	Ospemifene The metabolism of Erlotinib can be decreased when combined with Ospemifene.
Trametinib	Trametinib The serum concentration of Erlotinib can be decreased when it is combined with Trametinib.
Dolutegravir	Dolutegravir The metabolism of Dolutegravir can be decreased when combined with Erlotinib.
Afatinib	Afatinib Erlotinib may decrease the excretion rate of Afatinib which could result in a higher serum level.
Levomilnacipran	Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Erlotinib.
Vortioxetine	Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Erlotinib.
Perampanel	Perampanel The serum concentration of Erlotinib can be decreased when it is combined with Perampanel.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Erlotinib.
Lomitapide	Lomitapide The metabolism of Lomitapide can be decreased when combined with Erlotinib.
Ketorolac Injection	Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Erlotinib.
Simeprevir	Simeprevir The metabolism of Erlotinib can be decreased when combined with Simeprevir.
Sofosbuvir	Sofosbuvir Erlotinib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin	Dapagliflozin The metabolism of Erlotinib can be decreased when combined with Dapagliflozin.
Apremilast	Apremilast The metabolism of Erlotinib can be increased when combined with Apremilast.
Ceritinib	Ceritinib The metabolism of Erlotinib can be decreased when combined with Ceritinib.
Siltuximab Injection	Siltuximab Injection The serum concentration of Erlotinib can be decreased when it is combined with Siltuximab.
Eslicarbazepine	Eslicarbazepine The serum concentration of Eslicarbazepine can be decreased when it is combined with Erlotinib.
Belinostat Injection	Belinostat Injection The metabolism of Belinostat can be decreased when combined with Erlotinib.
Idelalisib	Idelalisib The metabolism of Idelalisib can be decreased when combined with Erlotinib.
Testosterone Injection	Testosterone Injection The serum concentration of Erlotinib can be decreased when it is combined with Testosterone.
Oritavancin Injection	Oritavancin Injection The serum concentration of Erlotinib can be decreased when it is combined with Oritavancin.
Vorapaxar	Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Erlotinib.
Hydrocodone	Hydrocodone The metabolism of Erlotinib can be decreased when combined with Hydrocodone.
Suvorexant	Suvorexant The metabolism of Suvorexant can be decreased when combined with Erlotinib.
Peginterferon Beta-1a Injection	Peginterferon Beta-1a Injection The metabolism of Erlotinib can be decreased when combined with Peginterferon beta-1a.
Olaparib	Olaparib The metabolism of Olaparib can be decreased when combined with Erlotinib.
Methamphetamine	Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Erlotinib.
Tasimelteon	Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Erlotinib.
Riociguat	Riociguat The metabolism of Riociguat can be decreased when combined with Erlotinib.
Lanreotide Injection	Lanreotide Injection The metabolism of Erlotinib can be decreased when combined with Lanreotide.
Pirfenidone	Pirfenidone The metabolism of Pirfenidone can be decreased when combined with Erlotinib.
Nintedanib	Nintedanib The metabolism of Nintedanib can be decreased when combined with Erlotinib.
Secukinumab Injection	Secukinumab Injection The metabolism of Erlotinib can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection The metabolism of Erlotinib can be decreased when combined with Risperidone.
Palbociclib	Palbociclib The metabolism of Palbociclib can be decreased when combined with Erlotinib.
Insulin Human Inhalation	Insulin Human Inhalation The metabolism of Erlotinib can be increased when combined with Insulin human.
Lenvatinib	Lenvatinib The serum concentration of Erlotinib can be decreased when it is combined with Lenvatinib.
Naloxegol	Naloxegol The metabolism of Erlotinib can be decreased when combined with Naloxegol.
Panobinostat	Panobinostat The metabolism of Erlotinib can be decreased when combined with Panobinostat.
Haloperidol Injection	Haloperidol Injection The risk or severity of QTc prolongation can be increased when Haloperidol is combined with Erlotinib.
Ivabradine	Ivabradine The risk or severity of QTc prolongation can be increased when Erlotinib is combined with Ivabradine.
Isavuconazonium Injection	Isavuconazonium Injection The serum concentration of Erlotinib can be decreased when it is combined with Isavuconazonium.
Sonidegib	Sonidegib The metabolism of Sonidegib can be decreased when combined with Erlotinib.
Rolapitant	Rolapitant The metabolism of Erlotinib can be decreased when combined with Rolapitant.
Prednisolone	Prednisolone The serum concentration of Erlotinib can be decreased when it is combined with Prednisolone.
Daclatasvir	Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Erlotinib.
Brexpiprazole	Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Erlotinib.
Ziprasidone Injection	Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Ziprasidone is combined with Erlotinib.
Cariprazine	Cariprazine The metabolism of Cariprazine can be decreased when combined with Erlotinib.
Insulin Degludec (rDNA Origin) Injection	Insulin Degludec (rDNA Origin) Injection The metabolism of Erlotinib can be increased when combined with Insulin degludec.
Cobimetinib	Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Erlotinib.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Erlotinib.
Osimertinib	Osimertinib The serum concentration of Erlotinib can be decreased when it is combined with Osimertinib.
Alectinib	Alectinib The metabolism of Alectinib can be decreased when combined with Erlotinib.
Ixazomib	Ixazomib The metabolism of Ixazomib can be decreased when combined with Erlotinib.
Rifapentine	Rifapentine The serum concentration of Erlotinib can be decreased when it is combined with Rifapentine.
Lesinurad	Lesinurad The metabolism of Erlotinib can be increased when combined with Lesinurad.
Amphotericin B Liposomal Injection	Amphotericin B Liposomal Injection The metabolism of Erlotinib can be decreased when combined with Amphotericin B.
Dexamethasone Injection	Dexamethasone Injection The serum concentration of Erlotinib can be decreased when it is combined with Dexamethasone.
Venetoclax	Venetoclax The metabolism of Venetoclax can be decreased when combined with Erlotinib.
Cobicistat	Cobicistat The metabolism of Erlotinib can be decreased when combined with Cobicistat.
Selexipag	Selexipag The metabolism of Selexipag can be decreased when combined with Erlotinib.
Obeticholic Acid	Obeticholic Acid The risk or severity of adverse effects can be increased when Obeticholic acid is combined with Erlotinib.
Diphenhydramine Injection	Diphenhydramine Injection The metabolism of Erlotinib can be decreased when combined with Diphenhydramine.
Furosemide Injection	Furosemide Injection The metabolism of Furosemide can be decreased when combined with Erlotinib.
Rucaparib	Rucaparib The metabolism of Rucaparib can be decreased when combined with Erlotinib.
Ribociclib	Ribociclib The metabolism of Erlotinib can be decreased when combined with Ribociclib.
Parathyroid Hormone Injection	Parathyroid Hormone Injection The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Erlotinib.
Brigatinib	Brigatinib The serum concentration of Erlotinib can be decreased when it is combined with Brigatinib.
Doxepin (Insomnia)	Doxepin (Insomnia) Doxepin can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Deutetrabenazine	Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Erlotinib.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Erlotinib.
Deflazacort	Deflazacort The metabolism of Erlotinib can be increased when combined with Deflazacort.
Safinamide	Safinamide The metabolism of Erlotinib can be decreased when combined with Safinamide.
Sarilumab Injection	Sarilumab Injection The serum concentration of Erlotinib can be decreased when it is combined with Sarilumab.
Midostaurin	Midostaurin The serum concentration of Erlotinib can be decreased when it is combined with Midostaurin.
Neratinib	Neratinib The metabolism of Neratinib can be decreased when combined with Erlotinib.
Abaloparatide Injection	Abaloparatide Injection The therapeutic efficacy of Abaloparatide can be decreased when used in combination with Erlotinib.
Enasidenib	Enasidenib The serum concentration of Erlotinib can be decreased when it is combined with Enasidenib.
Aprepitant/Fosaprepitant Injection	Aprepitant/Fosaprepitant Injection The serum concentration of Erlotinib can be decreased when it is combined with Fosaprepitant.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Erlotinib.
Delafloxacin	Delafloxacin The serum concentration of Erlotinib can be decreased when it is combined with Delafloxacin.
Abemaciclib	Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Erlotinib.
Acalabrutinib	Acalabrutinib The metabolism of Erlotinib can be decreased when combined with Acalabrutinib.
Letermovir	Letermovir The metabolism of Letermovir can be decreased when combined with Erlotinib.
Tetrabenazine	Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Erlotinib.
Ertugliflozin	Ertugliflozin Erlotinib may decrease the excretion rate of Ertugliflozin which could result in a higher serum level.
Buprenorphine Injection	Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Erlotinib.
Apalutamide	Apalutamide The metabolism of Erlotinib can be increased when combined with Apalutamide.
Fostamatinib	Fostamatinib The metabolism of Erlotinib can be decreased when combined with Fostamatinib.
Avatrombopag	Avatrombopag The metabolism of Erlotinib can be increased when combined with Avatrombopag.
Baricitinib	Baricitinib The metabolism of Baricitinib can be decreased when combined with Erlotinib.
Sodium Zirconium Cyclosilicate	Sodium Zirconium Cyclosilicate Sodium zirconium cyclosilicate can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lofexidine	Lofexidine The metabolism of Erlotinib can be decreased when combined with Lofexidine.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Erlotinib.
Encorafenib	Encorafenib The metabolism of Erlotinib can be decreased when combined with Encorafenib.
Binimetinib	Binimetinib The metabolism of Binimetinib can be decreased when combined with Erlotinib.
Ivosidenib	Ivosidenib The serum concentration of Erlotinib can be decreased when it is combined with Ivosidenib.
Lusutrombopag	Lusutrombopag Erlotinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Elagolix	Elagolix The metabolism of Elagolix can be decreased when combined with Erlotinib.
Doravirine	Doravirine The metabolism of Doravirine can be decreased when combined with Erlotinib.
Tafenoquine	Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Erlotinib.
Cannabidiol	Cannabidiol The metabolism of Erlotinib can be decreased when combined with Cannabidiol.
Dacomitinib	Dacomitinib The metabolism of Erlotinib can be decreased when combined with Dacomitinib.
Duvelisib	Duvelisib The metabolism of Duvelisib can be decreased when combined with Erlotinib.
Stiripentol	Stiripentol The metabolism of Erlotinib can be decreased when combined with Stiripentol.
Talazoparib	Talazoparib Erlotinib may decrease the excretion rate of Talazoparib which could result in a higher serum level.
Gilteritinib	Gilteritinib The risk or severity of QTc prolongation can be increased when Gilteritinib is combined with Erlotinib.
Glasdegib	Glasdegib The metabolism of Glasdegib can be decreased when combined with Erlotinib.
Lorlatinib	Lorlatinib The serum concentration of Lorlatinib can be decreased when it is combined with Erlotinib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection	Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Erlotinib.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The serum concentration of Erlotinib can be decreased when it is combined with Paclitaxel.
Rifamycin	Rifamycin The metabolism of Erlotinib can be increased when combined with Rifamycin.
Prucalopride	Prucalopride The metabolism of Prucalopride can be decreased when combined with Erlotinib.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Erlotinib can be increased when combined with Emapalumab.
Siponimod	Siponimod The metabolism of Siponimod can be decreased when combined with Erlotinib.
Acyclovir Ophthalmic	Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Erlotinib.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Erlotinib.
Esomeprazole Injection	Esomeprazole Injection Erlotinib can cause a decrease in the absorption of Esomeprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Alpelisib	Alpelisib The serum concentration of Erlotinib can be decreased when it is combined with Alpelisib.
Cladribine	Cladribine Erlotinib may decrease the excretion rate of Cladribine which could result in a higher serum level.
Darolutamide	Darolutamide Erlotinib may decrease the excretion rate of Darolutamide which could result in a higher serum level.
Triclabendazole	Triclabendazole The metabolism of Erlotinib can be decreased when combined with Triclabendazole.
Entrectinib	Entrectinib The risk or severity of QTc prolongation can be increased when Erlotinib is combined with Entrectinib.
Pexidartinib	Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Erlotinib.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Erlotinib.
Pitolisant	Pitolisant The serum concentration of Erlotinib can be decreased when it is combined with Pitolisant.
Fedratinib	Fedratinib The metabolism of Erlotinib can be decreased when combined with Fedratinib.
Lefamulin	Lefamulin Erlotinib may increase the QTc-prolonging activities of Lefamulin.
Phenytoin Injection	Phenytoin Injection The metabolism of Erlotinib can be increased when combined with Phenytoin.
Fosphenytoin Injection	Fosphenytoin Injection The metabolism of Erlotinib can be increased when combined with Fosphenytoin.
Zanubrutinib	Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Erlotinib.
Voxelotor	Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Erlotinib.
Lumateperone	Lumateperone The serum concentration of Lumateperone can be increased when it is combined with Erlotinib.
Ubrogepant	Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Erlotinib.
Tazemetostat	Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Erlotinib.
Cenobamate	Cenobamate The serum concentration of Erlotinib can be decreased when it is combined with Cenobamate.
Ozanimod	Ozanimod The metabolism of Ozanimod can be decreased when combined with Erlotinib.
Selumetinib	Selumetinib The metabolism of Selumetinib can be decreased when combined with Erlotinib.
Rimegepant	Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Erlotinib.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Erlotinib.
Sacituzumab govitecan-hziy Injection	Sacituzumab govitecan-hziy Injection The serum concentration of Sacituzumab govitecan can be increased when it is combined with Erlotinib.
Ripretinib	Ripretinib Erlotinib may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Selpercatinib	Selpercatinib The serum concentration of Erlotinib can be increased when it is combined with Selpercatinib.
Capmatinib	Capmatinib The serum concentration of Erlotinib can be increased when it is combined with Capmatinib.
Lemborexant	Lemborexant The metabolism of Lemborexant can be decreased when combined with Erlotinib.
Fenfluramine	Fenfluramine The metabolism of Erlotinib can be decreased when combined with Fenfluramine.
Fostemsavir	Fostemsavir The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Erlotinib.
Octreotide	Octreotide The serum concentration of Erlotinib can be increased when it is combined with Octreotide.
Pralsetinib	Pralsetinib The serum concentration of Erlotinib can be decreased when it is combined with Pralsetinib.
Opicapone	Opicapone The metabolism of Erlotinib can be decreased when combined with Opicapone.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Erlotinib can be decreased when it is combined with Satralizumab.
Relugolix	Relugolix The risk or severity of QTc prolongation can be increased when Relugolix is combined with Erlotinib.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Erlotinib can be decreased when combined with Drospirenone.
Viloxazine	Viloxazine The metabolism of Erlotinib can be decreased when combined with Viloxazine.
Vitamin E (Alpha-Tocopherol)	Vitamin E (Alpha-Tocopherol) The serum concentration of Vitamin E can be decreased when it is combined with Erlotinib.
Theophylline	Theophylline The metabolism of Theophylline can be decreased when combined with Erlotinib.
Indomethacin	Indomethacin The metabolism of Indomethacin can be decreased when combined with Erlotinib.
Mefenamic Acid	Mefenamic Acid The metabolism of Erlotinib can be decreased when combined with Mefenamic acid.
Naproxen	Naproxen The metabolism of Naproxen can be decreased when combined with Erlotinib.
Trazodone	Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Erlotinib.
Sodium Bicarbonate	Sodium Bicarbonate Sodium bicarbonate can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Hydroxyurea	Hydroxyurea The metabolism of Erlotinib can be decreased when combined with Hydroxyurea.
Phenobarbital	Phenobarbital The metabolism of Erlotinib can be increased when combined with Phenobarbital.
Methotrexate Injection	Methotrexate Injection The metabolism of Methotrexate can be decreased when combined with Erlotinib.
Primidone	Primidone The metabolism of Erlotinib can be increased when combined with Primidone.
Methsuximide	Methsuximide The risk or severity of QTc prolongation can be increased when Methsuximide is combined with Erlotinib.
Chlorpromazine	Chlorpromazine The serum concentration of Erlotinib can be decreased when it is combined with Chlorpromazine.
Diazepam	Diazepam The metabolism of Diazepam can be decreased when combined with Erlotinib.
Lorazepam	Lorazepam The metabolism of Lorazepam can be decreased when combined with Erlotinib.
Carmustine	Carmustine The metabolism of Erlotinib can be decreased when combined with Carmustine.
Amantadine	Amantadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Erlotinib.
Codeine	Codeine The metabolism of Erlotinib can be decreased when combined with Codeine.
Bromocriptine	Bromocriptine The metabolism of Erlotinib can be decreased when combined with Bromocriptine.
Tranylcypromine	Tranylcypromine The metabolism of Erlotinib can be decreased when combined with Tranylcypromine.
Phenelzine	Phenelzine The metabolism of Erlotinib can be decreased when combined with Phenelzine.
Tetracycline	Tetracycline The metabolism of Erlotinib can be decreased when combined with Tetracycline.
Prochlorperazine	Prochlorperazine The metabolism of Erlotinib can be decreased when combined with Prochlorperazine.
Thioridazine	Thioridazine The metabolism of Thioridazine can be decreased when combined with Erlotinib.
Trifluoperazine	Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Erlotinib.
Dapsone	Dapsone The metabolism of Dapsone can be decreased when combined with Erlotinib.
Sulfadiazine	Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Erlotinib.
Oxycodone	Oxycodone The metabolism of Erlotinib can be decreased when combined with Oxycodone.
Methadone	Methadone The serum concentration of Erlotinib can be decreased when it is combined with Methadone.
Oxybutynin	Oxybutynin The metabolism of Erlotinib can be decreased when combined with Oxybutynin.
Benztropine	Benztropine The metabolism of Erlotinib can be decreased when combined with Benzatropine.
Maprotiline	Maprotiline The metabolism of Erlotinib can be decreased when combined with Maprotiline.
Ibuprofen	Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Erlotinib.
Orphenadrine	Orphenadrine The metabolism of Erlotinib can be decreased when combined with Orphenadrine.
Perphenazine	Perphenazine The metabolism of Erlotinib can be decreased when combined with Perphenazine.
Azathioprine	Azathioprine The metabolism of Azathioprine can be decreased when combined with Erlotinib.
Fluphenazine	Fluphenazine The metabolism of Erlotinib can be decreased when combined with Fluphenazine.
Phentermine	Phentermine The metabolism of Phentermine can be decreased when combined with Erlotinib.
Amoxapine	Amoxapine The metabolism of Erlotinib can be decreased when combined with Amoxapine.
Sulfasalazine	Sulfasalazine Erlotinib may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Hydrocortisone	Hydrocortisone The serum concentration of Erlotinib can be decreased when it is combined with Hydrocortisone.
Doxorubicin	Doxorubicin The metabolism of Doxorubicin can be decreased when combined with Erlotinib.
Dactinomycin	Dactinomycin Erlotinib may decrease the excretion rate of Dactinomycin which could result in a higher serum level.
Carbamazepine	Carbamazepine The metabolism of Erlotinib can be increased when combined with Carbamazepine.
Clonidine	Clonidine The metabolism of Clonidine can be decreased when combined with Erlotinib.
Prazosin	Prazosin Erlotinib may decrease the excretion rate of Prazosin which could result in a higher serum level.
Hydralazine	Hydralazine The metabolism of Erlotinib can be decreased when combined with Hydralazine.
Cimetidine	Cimetidine Cimetidine can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Warfarin	Warfarin The serum concentration of Warfarin can be increased when it is combined with Erlotinib.
Loperamide	Loperamide The metabolism of Loperamide can be decreased when combined with Erlotinib.
Promethazine	Promethazine Promethazine can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Daunorubicin	Daunorubicin The metabolism of Daunorubicin can be decreased when combined with Erlotinib.
Nitrofurantoin	Nitrofurantoin Erlotinib may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin	Griseofulvin The serum concentration of Erlotinib can be decreased when it is combined with Griseofulvin.
Digoxin	Digoxin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Erlotinib.
Chloroquine	Chloroquine The metabolism of Chloroquine can be decreased when combined with Erlotinib.
Quinine	Quinine The serum concentration of Erlotinib can be decreased when it is combined with Quinine.
Ethosuximide	Ethosuximide The risk or severity of QTc prolongation can be increased when Ethosuximide is combined with Erlotinib.
Calcitriol	Calcitriol The serum concentration of Erlotinib can be decreased when it is combined with Calcitriol.
Triamterene	Triamterene The metabolism of Erlotinib can be decreased when combined with Triamterene.
Sulfinpyrazone	Sulfinpyrazone The serum concentration of Erlotinib can be decreased when it is combined with Sulfinpyrazone.
Clindamycin Injection	Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Erlotinib.
Secobarbital	Secobarbital The serum concentration of Erlotinib can be decreased when it is combined with Secobarbital.
Desipramine	Desipramine The metabolism of Desipramine can be decreased when combined with Erlotinib.
Amitriptyline	Amitriptyline The metabolism of Erlotinib can be decreased when combined with Amitriptyline.
Imipramine	Imipramine The metabolism of Imipramine can be decreased when combined with Erlotinib.
Probenecid	Probenecid The serum concentration of Erlotinib can be decreased when it is combined with Probenecid.
Quinidine	Quinidine The metabolism of Quinidine can be decreased when combined with Erlotinib.
Procainamide	Procainamide The metabolism of Procainamide can be decreased when combined with Erlotinib.
Isoniazid	Isoniazid The metabolism of Erlotinib can be decreased when combined with Isoniazid.
Rifampin	Rifampin The metabolism of Erlotinib can be increased when combined with Rifampicin.
Disopyramide	Disopyramide The risk or severity of QTc prolongation can be increased when Disopyramide is combined with Erlotinib.
Valproic Acid	Valproic Acid The metabolism of Valproic acid can be decreased when combined with Erlotinib.
Tamoxifen	Tamoxifen The serum concentration of Erlotinib can be decreased when it is combined with Tamoxifen.
Levothyroxine	Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Erlotinib.
Liothyronine	Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Erlotinib.
Methimazole	Methimazole The metabolism of Erlotinib can be decreased when combined with Methimazole.
Propylthiouracil	Propylthiouracil The therapeutic efficacy of Propylthiouracil can be decreased when used in combination with Erlotinib.
Tolbutamide	Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Erlotinib.
Dextromethorphan	Dextromethorphan The metabolism of Erlotinib can be decreased when combined with Dextromethorphan.
Cyclobenzaprine	Cyclobenzaprine The metabolism of Cyclobenzaprine can be decreased when combined with Erlotinib.
Niacin	Niacin The metabolism of Erlotinib can be decreased when combined with Niacin.
Doxylamine	Doxylamine The risk or severity of QTc prolongation can be increased when Doxylamine is combined with Erlotinib.
Cyproheptadine	Cyproheptadine The risk or severity of QTc prolongation can be increased when Cyproheptadine is combined with Erlotinib.
Clemastine	Clemastine The metabolism of Erlotinib can be decreased when combined with Clemastine.
Chlorpheniramine	Chlorpheniramine The metabolism of Erlotinib can be decreased when combined with Chlorpheniramine.
Brompheniramine	Brompheniramine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Erlotinib.
Meclizine	Meclizine The metabolism of Meclizine can be decreased when combined with Erlotinib.
Hydrochlorothiazide	Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Hydrochlorothiazide is combined with Erlotinib.
Chlorzoxazone	Chlorzoxazone The metabolism of Erlotinib can be decreased when combined with Chlorzoxazone.
Folic Acid	Folic Acid Erlotinib may decrease the excretion rate of Folic acid which could result in a higher serum level.
Danazol	Danazol The metabolism of Erlotinib can be decreased when combined with Danazol.
Disulfiram	Disulfiram The metabolism of Erlotinib can be decreased when combined with Disulfiram.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The metabolism of Erlotinib can be decreased when combined with Propranolol.
Minoxidil	Minoxidil The metabolism of Minoxidil can be decreased when combined with Erlotinib.
Nortriptyline	Nortriptyline The metabolism of Erlotinib can be decreased when combined with Nortriptyline.
Spironolactone	Spironolactone The metabolism of Erlotinib can be decreased when combined with Spironolactone.
Amphotericin B Injection	Amphotericin B Injection The metabolism of Erlotinib can be decreased when combined with Amphotericin B.
Nadolol	Nadolol The metabolism of Nadolol can be decreased when combined with Erlotinib.
Allopurinol	Allopurinol Erlotinib may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Oxytocin Injection	Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Erlotinib.
Papaverine	Papaverine The risk or severity of QTc prolongation can be increased when Papaverine is combined with Erlotinib.
Fluorouracil Injection	Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Erlotinib.
Colchicine	Colchicine The metabolism of Colchicine can be decreased when combined with Erlotinib.
Cephalexin	Cephalexin The metabolism of Cephalexin can be decreased when combined with Erlotinib.
Dacarbazine	Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Erlotinib.
Acetazolamide	Acetazolamide The metabolism of Erlotinib can be decreased when combined with Acetazolamide.
Calcitonin Salmon Injection	Calcitonin Salmon Injection The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Erlotinib.
Ketoconazole	Ketoconazole The metabolism of Erlotinib can be decreased when combined with Ketoconazole.
Thiotepa Injection	Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Erlotinib.
Vincristine Injection	Vincristine Injection The metabolism of Vincristine can be decreased when combined with Erlotinib.
Vinblastine	Vinblastine The serum concentration of Erlotinib can be decreased when it is combined with Vinblastine.
Metoprolol	Metoprolol The metabolism of Metoprolol can be decreased when combined with Erlotinib.
Hydroxyzine	Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Erlotinib.
Thiothixene	Thiothixene The risk or severity of QTc prolongation can be increased when Thiothixene is combined with Erlotinib.
Alprazolam	Alprazolam The metabolism of Alprazolam can be decreased when combined with Erlotinib.
Triazolam	Triazolam The metabolism of Triazolam can be decreased when combined with Erlotinib.
Hyoscyamine	Hyoscyamine The risk or severity of QTc prolongation can be increased when Hyoscyamine is combined with Erlotinib.
Trimethoprim	Trimethoprim The metabolism of Erlotinib can be decreased when combined with Trimethoprim.
Diltiazem	Diltiazem The metabolism of Diltiazem can be decreased when combined with Erlotinib.
Nifedipine	Nifedipine The serum concentration of Erlotinib can be decreased when it is combined with Nifedipine.
Timolol	Timolol The metabolism of Erlotinib can be decreased when combined with Timolol.
Verapamil	Verapamil The metabolism of Verapamil can be decreased when combined with Erlotinib.
Atenolol	Atenolol The metabolism of Erlotinib can be decreased when combined with Atenolol.
Pindolol	Pindolol The metabolism of Erlotinib can be decreased when combined with Pindolol.
Piroxicam	Piroxicam The metabolism of Piroxicam can be decreased when combined with Erlotinib.
Streptozocin	Streptozocin The metabolism of Erlotinib can be increased when combined with Streptozocin.
Etoposide	Etoposide The serum concentration of Erlotinib can be decreased when it is combined with Etoposide.
Glyburide	Glyburide The metabolism of Glyburide can be decreased when combined with Erlotinib.
Glipizide	Glipizide The metabolism of Glipizide can be decreased when combined with Erlotinib.
Indapamide	Indapamide The risk or severity of QTc prolongation can be increased when Indapamide is combined with Erlotinib.
Dicloxacillin	Dicloxacillin The serum concentration of Erlotinib can be decreased when it is combined with Dicloxacillin.
Nafcillin Injection	Nafcillin Injection The serum concentration of Erlotinib can be decreased when it is combined with Nafcillin.
Pentoxifylline	Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Erlotinib.
Pentamidine Injection	Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Erlotinib.
Labetalol	Labetalol The metabolism of Erlotinib can be decreased when combined with Labetalol.
Leuprolide Injection	Leuprolide Injection The risk or severity of QTc prolongation can be increased when Leuprolide is combined with Erlotinib.
Gemfibrozil	Gemfibrozil The metabolism of Erlotinib can be increased when combined with Gemfibrozil.
Guanabenz	Guanabenz The metabolism of Guanabenz can be decreased when combined with Erlotinib.
Ketoprofen	Ketoprofen The metabolism of Ketoprofen can be decreased when combined with Erlotinib.
Pimozide	Pimozide The metabolism of Pimozide can be decreased when combined with Erlotinib.
Flurbiprofen	Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Erlotinib.
Amiodarone	Amiodarone The metabolism of Amiodarone can be decreased when combined with Erlotinib.
Buspirone	Buspirone The metabolism of Erlotinib can be decreased when combined with Buspirone.
Lovastatin	Lovastatin The metabolism of Lovastatin can be decreased when combined with Erlotinib.
Ciprofloxacin	Ciprofloxacin The serum concentration of Erlotinib can be increased when it is combined with Ciprofloxacin.
Diclofenac	Diclofenac The metabolism of Diclofenac can be decreased when combined with Erlotinib.
Fluoxetine	Fluoxetine The serum concentration of Erlotinib can be increased when it is combined with Fluoxetine.
Nimodipine	Nimodipine The risk or severity of QTc prolongation can be increased when Nimodipine is combined with Erlotinib.
Interferon Alfa-2b Injection	Interferon Alfa-2b Injection The metabolism of Erlotinib can be decreased when combined with Interferon alfa-2b.
Clozapine	Clozapine The serum concentration of Erlotinib can be decreased when it is combined with Clozapine.
Idarubicin	Idarubicin The metabolism of Idarubicin can be decreased when combined with Erlotinib.
Ofloxacin	Ofloxacin The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Erlotinib.
Clarithromycin	Clarithromycin The metabolism of Clarithromycin can be decreased when combined with Erlotinib.
Felodipine	Felodipine The metabolism of Erlotinib can be decreased when combined with Felodipine.
Nabumetone	Nabumetone The metabolism of Erlotinib can be decreased when combined with Nabumetone.
Pravastatin	Pravastatin The metabolism of Pravastatin can be decreased when combined with Erlotinib.
Simvastatin	Simvastatin The metabolism of Simvastatin can be decreased when combined with Erlotinib.
Epoetin Alfa, Injection	Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Erlotinib.
Teniposide Injection	Teniposide Injection The metabolism of Teniposide can be decreased when combined with Erlotinib.
Itraconazole	Itraconazole The metabolism of Erlotinib can be decreased when combined with Itraconazole.
Rifabutin	Rifabutin The serum concentration of Erlotinib can be decreased when it is combined with Rifabutin.
Sotalol	Sotalol The metabolism of Sotalol can be decreased when combined with Erlotinib.
Zolpidem	Zolpidem The metabolism of Erlotinib can be decreased when combined with Zolpidem.
Doxazosin	Doxazosin The metabolism of Doxazosin can be decreased when combined with Erlotinib.
Isradipine	Isradipine The metabolism of Erlotinib can be decreased when combined with Isradipine.
Omeprazole	Omeprazole Omeprazole can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cisapride	Cisapride The metabolism of Erlotinib can be decreased when combined with Cisapride.
Fluvastatin	Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Erlotinib.
Venlafaxine	Venlafaxine The metabolism of Erlotinib can be decreased when combined with Venlafaxine.
Nizatidine	Nizatidine Nizatidine can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Famciclovir	Famciclovir The metabolism of Famciclovir can be decreased when combined with Erlotinib.
Fluvoxamine	Fluvoxamine The metabolism of Erlotinib can be decreased when combined with Fluvoxamine.
Nefazodone	Nefazodone The metabolism of Erlotinib can be decreased when combined with Nefazodone.
Lamotrigine	Lamotrigine The risk or severity of QTc prolongation can be increased when Lamotrigine is combined with Erlotinib.
Losartan	Losartan The metabolism of Losartan can be decreased when combined with Erlotinib.
Tramadol	Tramadol The metabolism of Tramadol can be decreased when combined with Erlotinib.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Erlotinib can be decreased when combined with Vinorelbine.
Moexipril	Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Erlotinib.
Lansoprazole	Lansoprazole Lansoprazole can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ifosfamide Injection	Ifosfamide Injection The serum concentration of Erlotinib can be decreased when it is combined with Ifosfamide.
Nicardipine	Nicardipine The metabolism of Nicardipine can be decreased when combined with Erlotinib.
Bupropion	Bupropion The metabolism of Erlotinib can be decreased when combined with Bupropion.
Ticlopidine	Ticlopidine The metabolism of Erlotinib can be decreased when combined with Ticlopidine.
Saquinavir	Saquinavir The metabolism of Saquinavir can be decreased when combined with Erlotinib.
Nisoldipine	Nisoldipine The metabolism of Erlotinib can be decreased when combined with Nisoldipine.
Lamivudine	Lamivudine Erlotinib may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole	Riluzole Erlotinib may decrease the excretion rate of Riluzole which could result in a higher serum level.
Anastrozole	Anastrozole The metabolism of Erlotinib can be decreased when combined with Anastrozole.
Indinavir	Indinavir The metabolism of Erlotinib can be decreased when combined with Indinavir.
Ritonavir	Ritonavir The metabolism of Erlotinib can be decreased when combined with Ritonavir.
Docetaxel Injection	Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Erlotinib.
Clomipramine	Clomipramine The metabolism of Clomipramine can be decreased when combined with Erlotinib.
Zafirlukast	Zafirlukast The metabolism of Zafirlukast can be decreased when combined with Erlotinib.
Mirtazapine	Mirtazapine The metabolism of Erlotinib can be decreased when combined with Mirtazapine.
Topiramate	Topiramate The metabolism of Erlotinib can be increased when combined with Topiramate.
Zileuton	Zileuton The metabolism of Zileuton can be decreased when combined with Erlotinib.
Insulin Lispro Injection	Insulin Lispro Injection The metabolism of Erlotinib can be increased when combined with Insulin lispro.
Donepezil	Donepezil The metabolism of Donepezil can be decreased when combined with Erlotinib.
Nelfinavir	Nelfinavir The metabolism of Nelfinavir can be decreased when combined with Erlotinib.
Azithromycin	Azithromycin The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Erlotinib.
Loratadine	Loratadine The metabolism of Erlotinib can be decreased when combined with Loratadine.
Carvedilol	Carvedilol The metabolism of Carvedilol can be decreased when combined with Erlotinib.
Nilutamide	Nilutamide The metabolism of Erlotinib can be decreased when combined with Nilutamide.
Flutamide	Flutamide The metabolism of Erlotinib can be decreased when combined with Flutamide.
Selegiline	Selegiline The metabolism of Selegiline can be decreased when combined with Erlotinib.
Bicalutamide	Bicalutamide The metabolism of Erlotinib can be decreased when combined with Bicalutamide.
Sertraline	Sertraline The metabolism of Erlotinib can be decreased when combined with Sertraline.
Propafenone	Propafenone The metabolism of Erlotinib can be decreased when combined with Propafenone.
Raloxifene	Raloxifene The metabolism of Raloxifene can be decreased when combined with Erlotinib.
Irbesartan	Irbesartan The metabolism of Irbesartan can be decreased when combined with Erlotinib.
Tamsulosin	Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Erlotinib.
Finasteride	Finasteride The metabolism of Finasteride can be decreased when combined with Erlotinib.
Quetiapine	Quetiapine The metabolism of Quetiapine can be decreased when combined with Erlotinib.
Cetirizine	Cetirizine The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Erlotinib.
Paroxetine	Paroxetine The metabolism of Erlotinib can be decreased when combined with Paroxetine.
Citalopram	Citalopram The metabolism of Erlotinib can be decreased when combined with Citalopram.
Capecitabine	Capecitabine The serum concentration of Erlotinib can be increased when it is combined with Capecitabine.
Efavirenz	Efavirenz The serum concentration of Erlotinib can be decreased when it is combined with Efavirenz.
Abacavir	Abacavir The metabolism of Abacavir can be decreased when combined with Erlotinib.
Sildenafil	Sildenafil The metabolism of Erlotinib can be decreased when combined with Sildenafil.
Pioglitazone	Pioglitazone The serum concentration of Pioglitazone can be increased when it is combined with Erlotinib.
Celecoxib	Celecoxib The metabolism of Celecoxib can be decreased when combined with Erlotinib.
Rosiglitazone	Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Erlotinib.
Tolterodine	Tolterodine The metabolism of Erlotinib can be decreased when combined with Tolterodine.
Thalidomide	Thalidomide The metabolism of Erlotinib can be increased when combined with Thalidomide.
Aluminum Hydroxide	Aluminum Hydroxide Aluminum hydroxide can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nateglinide	Nateglinide The metabolism of Nateglinide can be decreased when combined with Erlotinib.
Galantamine	Galantamine The metabolism of Erlotinib can be decreased when combined with Galantamine.
Rabeprazole	Rabeprazole Rabeprazole can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Terbinafine	Terbinafine The serum concentration of Erlotinib can be decreased when it is combined with Terbinafine.