Drug & supplement interaction

Sweet Cicely + Isocarboxazid

Isocarboxazid brand name: Marplan.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Sweet Cicely and Isocarboxazid in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Sweet Cicely and Isocarboxazid

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Isocarboxazid and Sweet Cicely in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Sweet Cicely at all — not against Isocarboxazid, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Sweet Cicely safety at a glance

Sweet Cicely overall Use caution Likely safe in small culinary amounts, but medicinal use is poorly studied.
Pregnancy Avoid Not enough safety data, so it is best avoided in medicinal amounts during pregnancy.
Breastfeeding Avoid Safety has not been studied, so avoid medicinal use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Isocarboxazid and Sweet Cicely? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Isocarboxazid’s Own FDA Label Lists

This is not an interaction — none of it involves Sweet Cicely. These are the most notable effects listed in the ADVERSE REACTIONS section of Isocarboxazid’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both.

  • Dry mouth
  • Dizziness
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Isocarboxazid. Read the label on DailyMed › Sweet Cicely’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Sweet Cicely side to compare — that is a limit of the record, not a statement that Sweet Cicely has no side effects.

Everything else you take

See Every Supplement That Interacts With Isocarboxazid

This page covers Sweet Cicely only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Isocarboxazid page lists 81 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Bitter Orange (major), Brewer's Yeast (major) and Cowhage (major).

By severity: 14 major · 55 moderate · 12 minor.

From our pharmacist’s overview on the Isocarboxazid page

“Isocarboxazid (Marplan) is an MAOI antidepressant, and that drug class carries some of the sharpest supplement and food hazards in the pharmacy, so read this list closely rather than skimming it. Fourteen of the 81 entries rate major, and most of the danger runs through tyramine.”

Reviewed by 2 · Jul 18, 2026

Open the Isocarboxazid interaction page

How much people look this up

Where Sweet Cicely and Isocarboxazid Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Sweet Cicely
Steady interest

#1,266 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Isocarboxazid
Steady interest

#2,132 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Sweet Cicely and Isocarboxazid records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Sweet Cicely

What is Sweet Cicely?

  • Digestive upset and gas
  • Mild cough and chest complaints
  • As a natural sweetener for tart foods
  • Loss of appetite
  • General tonic

Sweet Cicely is a mild, anise-flavored garden herb traditionally used in cooking and folk remedies for digestion and coughs. There is very little modern scientific research to confirm any health benefits, but it is generally considered safe in food amounts. Talk to a pharmacist or doctor before using it as a medicine, especially if you are pregnant or breastfeeding.

Myrrhis odorata · Apiaceae · Leaves, seeds, and roots · Fresh or dried herb, tea, culinary herb, occasionally tincture

An interaction check asks whether these two react with each other — it does not ask whether Sweet Cicely is a good idea for someone in your situation. Here is what our Sweet Cicely record says about it on its own.

Sweet Cicely: dosing

There is no established, standardized medicinal dose for Sweet Cicely. Most use is culinary, where the fresh or dried leaves and seeds are added to food or steeped as a mild tea.If you choose to use a commercial Sweet Cicely product, follow the directions on the product label and do not exceed the recommended amount.

From our Sweet Cicely monograph — the full record covers uses, side effects and every documented interaction.

Read the full Sweet Cicely monograph & all interactions
Medication

About Isocarboxazid

What Is Isocarboxazid Used For?

Brand name: Marplan

Marplan (isocarboxazid) is indicated for the treatment of depression — specifically, major depressive disorder. Because it carries serious risks, it is not a first-choice antidepressant. Marplan is generally reserved for patients who have not responded adequately to other antidepressants.

Clinical trials showed Marplan to be effective in adult outpatients with major depressive disorder, including those whose depression was accompanied by anxiety symptoms such as panic or phobias. Marplan is not approved for use in children or adolescents.

See full Isocarboxazid drug information
Keep checking

Other Drugs & Sweet Cicely

Browse every other medication we’ve checked against Sweet Cicely — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Sweet Cicely against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Sweet Cicely list.

See the full Sweet Cicely interactions page
See every supplement checked against Isocarboxazid, ranked by severity
Sources

Sources & How We Checked

We checked Sweet Cicely against Isocarboxazid in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Sweet Cicely monograph › Uses, safety, and every drug interaction in one place Isocarboxazid supplement interactions › Every supplement checked against Isocarboxazid, ranked by severity Isocarboxazid drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Sweet Cicely and Isocarboxazid Together: Common Questions

Is it safe to take Sweet Cicely with Isocarboxazid?
We do not list a known interaction between Sweet Cicely and Isocarboxazid. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Isocarboxazid interact with any supplements?
Yes. Isocarboxazid has documented interactions with 81 supplements in our database — Sweet Cicely is not one of them. The Isocarboxazid interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Isocarboxazid and Sweet Cicely?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.