Drug & supplement interaction

Tomato + Aluminum Acetate

Aluminum Acetate brand name: Burow's Solution.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Tomato and Aluminum Acetate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Tomato and Aluminum Acetate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Aluminum Acetate and Tomato in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Tomato at all — not against Aluminum Acetate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Tomato safety at a glance

Tomato overall Generally safe Tomato as a food is safe for most people; concentrated supplements are less studied.
Pregnancy Likely Safe When the tomato fruit or its products are consumed in typical food amounts. There is insufficient reliable information available about the safety of tomato extr... Read the full pregnancy detail
Breastfeeding Likely Safe When the tomato fruit or its products are consumed in typical food amounts. There is insufficient reliable information available about the safety of tomato extr... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Aluminum Acetate and Tomato? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Tomato Itself Has Been Linked To

This is not an interaction — nothing below involves Aluminum Acetate. It is the side-effect record for Tomato on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Tomato, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A slow heartbeat Worth acting on Additional detail

    “Orally, tomato leaves and ripe or unripe tomato fruit are well tolerated in typical food amounts. Tomato extracts also seem to be well tolerated. Tomatine, a glycoalkaloid found in tomato leaves and unripe green tomatoes, can cause serious side effects when consumed in excessive amounts.

    Serious Adverse Effects (Rare):

    Orally: Bradycardia, diarrhea, respiratory disturbances, spasms, vomiting, and death with excessive…”

    Tomato · Natural Medicines adverse-effect record, reported in diarrhea.

  • Dizziness / Headache Additional detail

    “Orally, the glycoalkaloid tomatine in tomato leaf or green tomatoes can cause dizziness, stupor, headache, and mild spasms when consumed in excessive amounts (18,102957).”

    Tomato · Natural Medicines adverse-effect record, reported in cluster headache.

    2 sources cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    2. 102957. Friedman M. Tomato Glycoalkaloids: Role in the Plant and in the Diet. J Agric Food Chem. 2002;50(21):5751-80. PubMed
  • Diarrhea / Vomiting Additional detail

    “Orally, the glycoalkaloid tomatine in tomato leaf or green tomatoes can cause severe mucous membrane irritation, vomiting, diarrhea, and colic when consumed in excessive amounts (18,102957).”

    Tomato · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    2. 102957. Friedman M. Tomato Glycoalkaloids: Role in the Plant and in the Diet. J Agric Food Chem. 2002;50(21):5751-80. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Tomato — expand a row for the licensed statement it rests on. We haven’t matched Aluminum Acetate to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Aluminum Acetate.

Special populations

Tomato in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When the tomato fruit or its products are consumed in typical food amounts. There is insufficient reliable information available about the safety of tomato extracts when used during pregnancy or lactation; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Aluminum Acetate

This page covers Tomato only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Aluminum Acetate page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Aluminum Acetate page

“Aluminum acetate (Burow's Solution) is the soak or compress people reach for with weepy rashes, athlete's foot, or swimmer's ear, and its three supplement interactions on file all come down to what else touches that same patch of skin. None is rated major, and this is a list most people can handle with a little attention rather than al…”

Reviewed by 2 · Jul 18, 2026

Open the Aluminum Acetate interaction page

One more smart check

Taking Tomato as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2,820 real supplement products containing Tomato, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tomato. Even though Tomato itself has no known interaction with Aluminum Acetate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Tomato and Aluminum Acetate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tomato
Top 10%

#139 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Aluminum Acetate
Steady interest

#1,938 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tomato reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Tomato and Aluminum Acetate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Tomato

What is Tomato?

  • Heart health support
  • Prostate health
  • Antioxidant support
  • Skin protection from sun damage
  • General nutrition

Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people. Concentrated tomato or lycopene supplements are marketed for heart and prostate health, but the evidence is mixed and far from proven. Talk to your pharmacist or doctor before using high-dose supplements, especially if you are pregnant or have a medical condition.

Solanum lycopersicum · Solanaceae · Fruit (and extracts such as lycopene from the fruit and skin) · Whole fruit, juice, paste, tomato extract capsules, lycopene supplements

An interaction check asks whether these two react with each other — it does not ask whether Tomato is a good idea for someone in your situation. Here is what our Tomato record says about it on its own.

Tomato: dosing

There is no official standardized dose of tomato or lycopene supplements, and a proven effective amount has not been established. Tomatoes are best enjoyed simply as part of a balanced diet.If you choose to use a tomato extract or lycopene supplement, follow the directions on the product label and do not exceed the recommended amount.

From our Tomato monograph — the full record covers uses, side effects and every documented interaction.

Read the full Tomato monograph & all interactions
Medication

About Aluminum Acetate

What Is Aluminum Acetate Used For?

Brand name: Burow's Solution

Aluminum acetate is applied to the skin to temporarily ease the itch, irritation, and discomfort of a range of common skin conditions. Most products — including Tricalm Hydrogel, TriCalm, and Dermeleve cream — are used for poison ivy, poison oak, poison sumac, insect bites, athlete's foot, and rashes caused by soaps, detergents, cosmetics, or jewelry.

Dermeleve cream also lists minor burns among its uses. Dermeleve Anti Itch Scalp Serum is specifically formulated for scalp itch and rashes from soaps, detergents, or cosmetics applied to the scalp. The ZO Skin Health powder products target rashes from soaps, detergents, cosmetics, or jewelry.

Most-Reported Side Effects for Aluminum Acetate

From FAERS, the FDA’s public side-effect reporting system (40 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Headache 19 reports
Hypersensitivity 16 reports
Nausea 16 reports
Therapeutic product effect decreased 16 reports
Contraindicated product administered 6 reports
See full Aluminum Acetate drug information
Keep checking

Other Drugs & Tomato

Browse every other medication we’ve checked against Tomato — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Tomato against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Tomato list.

See the full Tomato interactions page
See every supplement checked against Aluminum Acetate, ranked by severity
Evidence & sources

Tomato References

The 3 references that drive our Tomato monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Asero R, Mistrello G, Amato S. Airborne allergy to tomato proteins. Allergy. 2010;65(12):1626-7. PubMed
  3. Friedman M. Tomato Glycoalkaloids: Role in the Plant and in the Diet. J Agric Food Chem. 2002;50(21):5751-80. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Tomato and Aluminum Acetate Together: Common Questions

Is it safe to take Tomato with Aluminum Acetate?
We do not list a known interaction between Tomato and Aluminum Acetate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Aluminum Acetate interact with any supplements?
Yes. Aluminum Acetate has documented interactions with 3 supplements in our database — Tomato is not one of them. The Aluminum Acetate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Tomato monograph Uses, safety profile, and every drug interaction in one place Aluminum Acetate drug information The full plain-English guide to this medication Aluminum Acetate supplement interactions Every supplement checked against Aluminum Acetate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Aluminum Acetate and Tomato?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.